Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1967417 | 0.83 | KMT2A (0.42) | KMT2APOLBCYP1A2NQO2MAPT | |
| SCHEMBL206867 | 0.75 | NOS1 (0.38) | CYP1A2ALDH1A1CHEK1PIM1RPS6KA3 | |
| SCHEMBL208893 | 0.75 | KDM4E (0.36) | KMT2ACYP1A2MAPTKDM4EALDH1A1 | |
| SCHEMBL207659 | 0.75 | F7 (0.42) | KMT2APOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL5981619 | 0.75 | DYRK1A (0.42) | KMT2APOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL7221951 | 0.75 | ALDH1A1 (0.42) | KMT2APOLBKDM4EALDH1A1CHEK1 | |
| SCHEMBL15157341 | 0.75 | KIF11 (0.40) | ALDH1A1HPGDHTR1A | |
| SCHEMBL5981617 | 0.75 | TERT (0.47) | MAPTKDM4EALDH1A1 | |
| SCHEMBL356787 | 0.75 | MEN1 (0.46) | KMT2APOLBCYP1A2NQO2MAPT | |
| SCHEMBL416318 | 0.74 | FABP6 (0.41) | KMT2APOLBCYP1A2NQO2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 542 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362775-B1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2015-08-05 | — | — | EP | claimed |
| US-8697685-B2 | Chemical compounds | GLAXOSMITHKLINE LLC (US) | 2014-04-15 | — | — | US | claimed |
| EP-1720835-B1 | NOVEL GUANIDINYL-SUBSTITUTED HYDROXY-6-PHENYLPHENANTHRIDINES AS EFFECTIVE PHOSPHODIESTERASE (PDE) 4 INHIBITORS | NYCOMED GMBH (DE) | 2012-12-12 | — | — | EP | claimed |
| US-20110275611-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC | 2011-11-10 | — | — | US | claimed |
| EP-2362775-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2011-09-07 | — | — | EP | claimed |
| JP-4728259-B2 | — | — | 2011-07-20 | — | — | JP | claimed |
| WO-2010059658-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-05-27 | — | — | WO | claimed |
| US-20080207683-A1 | BIARYL-SUBSTITUTED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. | 2008-08-28 | — | — | US | claimed |
| US-20070167482-A1 | Novel guanidinyl-substituted hydroxy-6-phenylphenanthridines as effective phosphodiesterase (pde) 4 inhibitors | ALTANA PHARMA AG (DE) | 2007-07-19 | — | — | US | claimed |
| EP-1720835-A1 | NOVEL GUANIDINYL-SUBSTITUTED HYDROXY-6-PHENYLPHENANTHRIDINES AS EFFECTIVE PHOSPHODIESTERASE (PDE) 4 INHIBITORS | Altana Pharma AG (DE) | 2006-11-15 | — | — | EP | claimed |
| US-20060116518-A1 | Novel phenanthridines | ALTANA PHARMA AG (DE) | 2006-06-01 | — | — | US | claimed |
| EP-1581533-A2 | NOVEL BENZONAPHTHYRIDINES | ALTANA Pharma AG (DE) | 2005-10-05 | — | — | EP | claimed |
| WO-2004018465-A9 | BENZONAPHTHYRIDINES WITH PDE 3/4 INHIBITING ACTIVITY | ALTANA PHARMA AG (DE) | 2005-09-15 | — | — | WO | claimed |
| WO-2005077906-A1 | NOVEL GUANIDINYL-SUBSTITUTED HYDROXY-6-PHENYLPHENENTHRIDINES AS EFFECTIVE PHOSPHODIESTERASE (PDE) 4 INHIBITORS | ALTANA PHARMA AG (DE) | 2005-08-25 | — | — | WO | claimed |
| EP-1537086-A2 | NOVEL PHENANTHRIDINES | ALTANA Pharma AG (DE) | 2005-06-08 | — | — | EP | claimed |
| WO-2004018431-A2 | NOVEL PHENANTHRIDINES | ALTANA PHARMA AG (DE) | 2004-03-04 | — | — | WO | claimed |
| WO-2004018465-A2 | BENZONAPHTHYRIDINES WITH PDE 3/4 INHIBITING ACTIVITY | ALTANA PHARMA AG (DE) | 2004-03-04 | — | — | WO | claimed |
| CN-1225013-A | Non-peptide G-CSF mimetics | SMITHKLINE BEECHAM CORP (US) | 1999-08-04 | — | — | CN | claimed |
| US-11944618-B2 | Subcutaneous delivery of polymer conjugates of therapeutic agents | SERINA THERAPEUTICS, INC. (US) | 2024-04-02 | — | — | US | disclosed |
| EP-0012909-A1 | Benzimidazolyl-2-alkane-phosphonic acids and their salts, process for their preparation and their use as corrosion inhibitors or wetting agents | BAYER AG (DE) | 1980-07-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11944618-B2 | Subcutaneous delivery of polymer conjugates of therapeutic agents | CD44, CD47, LNPEP | KMT2A 2825/4885POLB 1954/4885CYP1A2 4666/4885 |
| US-20110275611-A1 | CHEMICAL COMPOUNDS | PDK1, PDK2, PDK3 | KMT2A 2173/4885POLB 3721/4885CYP1A2 1859/4885 |
| US-20070167482-A1 | Novel guanidinyl-substituted hydroxy-6-phenylphenanthridines as effective phosphodiesterase (pde) 4 inhibitors | PDE4A, PDE3A, PDE4B | KMT2A 2822/4885POLB 2755/4885CYP1A2 483/4885 |
| US-20060116518-A1 | Novel phenanthridines | PDE4A, PDE4B, PDE3A | KMT2A 2155/4885POLB 2416/4885CYP1A2 185/4885 |
| US-20080207683-A1 | BIARYL-SUBSTITUTED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | CTSS, CTSK, CTSZ | KMT2A 4149/4885POLB 2119/4885CYP1A2 2244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.