SCHEMBL21391651

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18326859	0.86	KIF11 (0.54)	CYP19A1MEN1KMT2ARAB9AKIF11
	SCHEMBL21391603	0.85	MEN1 (0.51)	MEN1KMT2AALDH1A1HPGDKDM4E
	SCHEMBL13203143	0.85	CYP19A1 (0.52)	CYP19A1MEN1KMT2ARAB9AKIF11
	SCHEMBL21391607	0.84	MEN1 (0.41)	CYP19A1MEN1KMT2ARAB9AKIF11
	SCHEMBL25629739	0.84	MEN1 (0.59)	MEN1KMT2ARAB9AALDH1A1HPGD
	SCHEMBL21391652	0.82	ENPP3 (0.40)	CYP19A1MEN1KMT2ARAB9AALDH1A1
	SCHEMBL24210980	0.81	MEN1 (0.56)	MEN1KMT2ARAB9AALDH1A1HPGD
	SCHEMBL21391608	0.81	MEN1 (0.39)	CYP19A1MEN1KMT2ARAB9AKIF11
	SCHEMBL19862789	0.81	KIF11 (0.57)	CYP19A1MEN1KMT2ARAB9AKIF11
	SCHEMBL19735237	0.80	KIF11 (0.56)	CYP19A1MEN1KMT2ARAB9AKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.