SCHEMBL21391652

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21391604	0.88	NR1H4 (0.44)	ENPP3ENPP1NR1H4RAB9AMEN1
	SCHEMBL21391607	0.87	MEN1 (0.41)	RAB9AMEN1KMT2AALDH1A1MAPT
	SCHEMBL27342590	0.83	NR1H4 (0.32)	ENPP3ENPP1ESR1ESR2NR1H4
	SCHEMBL21391651	0.82	CYP19A1 (0.49)	RAB9AMEN1KMT2AALDH1A1MAPT
	SCHEMBL23894207	0.82	ENPP3 (0.30)	ENPP3ENPP1ESR1ESR2
	SCHEMBL28196231	0.82	ENPP3 (0.54)	ENPP3ENPP1ESR1ESR2RAB9A
	SCHEMBL21391608	0.81	MEN1 (0.39)	RAB9AMEN1KMT2AALDH1A1MAPT
	SCHEMBL21391744	0.81	NR1H4 (0.42)	ENPP3ENPP1NR1H4RAB9AMEN1
	SCHEMBL21391673	0.81	MEN1 (0.44)	RAB9AMEN1KMT2AALDH1A1MAPT
	SCHEMBL12258363	0.79	MEN1 (0.53)	ENPP3ENPP1ESR1ESR2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.