SCHEMBL216222

SCHEMBL216222

CCOC(=O)C(C)=COC(=O)C(N=Nc1ccc(C(=O)O)cc1)C(C)=O

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.38
CES2 O00748 6/20 0.38
CES1 P23141 6/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
MAPT P10636 3/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 1/20 0.36
TRPA1 O75762 1/20 0.35
POLB P06746 1/20 0.35
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217658 0.91 MAPT (0.47) ACHECES2CES1MEN1KMT2A
SCHEMBL217696 0.89 RAB9A (0.41) ACHECES2CES1MEN1KMT2A
SCHEMBL218279 0.88 CES2 (0.37) ACHECES2CES1MEN1KMT2A
SCHEMBL217788 0.84 MEN1 (0.37) ACHECES2CES1MEN1KMT2A
SCHEMBL217009 0.84 MAPT (0.46) ACHECES2CES1MEN1KMT2A
SCHEMBL5699058 0.73 RAB9A (0.56) ACHEMEN1KMT2AMAPTNPC1
SCHEMBL3661065 0.73 TRPA1 (0.52) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL8437177 0.72 ALDH1A1 (0.47) ACHECES2CES1MEN1KMT2A
SCHEMBL8437175 0.72 ALDH1A1 (0.47) ACHECES2CES1MEN1KMT2A
SCHEMBL11767203 0.70 NPC1 (0.41) MEN1KMT2AMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060063105-A1 Negative-working photoimageable bottom antireflective coating OBERLANDER JOSEPH E 2006-03-23 US claimed
EP-1466214-A2 NEGATIVE-WORKING PHOTOIMABEABLE BOTTOM ANTIREFLECTIVE COATING AZ Electronic Materials USA Corp. (US) 2004-10-13 EP claimed
US-20030215736-A1 Negative-working photoimageable bottom antireflective coating AZ ELECTRONIC MATERIALS USA CORP. 2003-11-20 US claimed
WO-2003058345-A2 NEGATIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING CLARIANT INTERNATIONAL LTD (CH) 2003-07-17 WO claimed
US-8088548-B2 Bottom antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-01-03 US disclosed
EP-2212273-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2010-08-04 EP disclosed
WO-2009053832-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2009-04-30 WO disclosed
US-20090104559-A1 Bottom Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2009-04-23 US disclosed
US-20060063105-A1 Negative-working photoimageable bottom antireflective coating OBERLANDER JOSEPH E 2006-03-23 US disclosed
EP-1466214-A2 NEGATIVE-WORKING PHOTOIMABEABLE BOTTOM ANTIREFLECTIVE COATING AZ Electronic Materials USA Corp. (US) 2004-10-13 EP disclosed
US-20030215736-A1 Negative-working photoimageable bottom antireflective coating AZ ELECTRONIC MATERIALS USA CORP. 2003-11-20 US disclosed
WO-2003058345-A2 NEGATIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING CLARIANT INTERNATIONAL LTD (CH) 2003-07-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104559-A1 Bottom Antireflective Coating Compositions SDC2, S100A9, MYH9 ACHE 3212/4885CES2 3197/4885CES1 3825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.