SCHEMBL217009

SCHEMBL217009

CCOC(=O)C(C)=COC(=O)C(N=Nc1ccc([N+](=O)[O-])cc1)C(C)=O

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
GAA P10253 2/20 0.39
GLO1 Q04760 1/20 0.38
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
LMNA P02545 4/20 0.36
CES2 O00748 1/20 0.36
ACHE P22303 1/20 0.36
CES1 P23141 1/20 0.36
PKM P14618 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NOS1 P29475 1/20 0.36
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218279 0.85 CES2 (0.37) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL217788 0.84 MEN1 (0.37) MAPTKMT2AMEN1ALDH1A1GAA
SCHEMBL216222 0.84 ACHE (0.38) MAPTKMT2AMEN1ALDH1A1LMNA
SCHEMBL217658 0.84 MAPT (0.47) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL217696 0.82 RAB9A (0.41) MAPTKMT2AMEN1ALDH1A1CES2
SCHEMBL3034223 0.70 GLO1 (0.54) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL3034226 0.70 GLO1 (0.54) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL17182750 0.69 MAPT (0.59) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL17182751 0.69 MAPT (0.59) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL28627286 0.68 MAOB (0.50) MAPTKMT2AMEN1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088548-B2 Bottom antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-01-03 US disclosed
EP-2212273-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2010-08-04 EP disclosed
US-7553905-B2 Anti-reflective coatings AZ ELECTRONIC MATERIALS USA CORP. (US) 2009-06-30 US disclosed
WO-2009053832-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2009-04-30 WO disclosed
US-20090104559-A1 Bottom Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2009-04-23 US disclosed
EP-1966255-A1 ANTI-REFLECTIVE COATINGS AZ Electronic Materials USA Corp. (US) 2008-09-10 EP disclosed
WO-2007052132-A1 ANTI-REFLECTIVE COATINGS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2007-05-10 WO disclosed
US-20070099108-A1 Anti-reflective coatings MERCK PATENT GMBH (DE) 2007-05-03 US disclosed
US-20060063105-A1 Negative-working photoimageable bottom antireflective coating OBERLANDER JOSEPH E 2006-03-23 US disclosed
EP-1466214-A2 NEGATIVE-WORKING PHOTOIMABEABLE BOTTOM ANTIREFLECTIVE COATING AZ Electronic Materials USA Corp. (US) 2004-10-13 EP disclosed
US-20030215736-A1 Negative-working photoimageable bottom antireflective coating AZ ELECTRONIC MATERIALS USA CORP. 2003-11-20 US disclosed
WO-2003058345-A2 NEGATIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING CLARIANT INTERNATIONAL LTD (CH) 2003-07-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104559-A1 Bottom Antireflective Coating Compositions SDC2, S100A9, MYH9 MAPT 971/4885KMT2A 1852/4885MEN1 883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.