SCHEMBL217696

SCHEMBL217696

CCOC(=O)C(C)=COC(=O)C(N=Nc1ccc(C(=O)OC)cc1)C(C)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.41
NPC1 O15118 8/20 0.41
SMN1; SMN2 Q16637 7/20 0.41
MAPT P10636 6/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 2/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ACHE P22303 2/20 0.39
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217658 0.93 MAPT (0.47) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL216222 0.89 ACHE (0.38) RAB9ANPC1MAPTALDH1A1MEN1
SCHEMBL218279 0.86 CES2 (0.37) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL217788 0.83 MEN1 (0.37) RAB9ANPC1MAPTALDH1A1HPGD
SCHEMBL3661166 0.77 RAB9A (0.49) RAB9ANPC1SMN1; SMN2MAPTCASP3
SCHEMBL5699058 0.74 RAB9A (0.56) RAB9ANPC1SMN1; SMN2MAPTCASP3
SCHEMBL4698545 0.71 RAB9A (0.50) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL28848848 0.71 MAPT (0.47) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL11767203 0.68 NPC1 (0.41) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL8437177 0.68 ALDH1A1 (0.47) RAB9ANPC1SMN1; SMN2MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060063105-A1 Negative-working photoimageable bottom antireflective coating OBERLANDER JOSEPH E 2006-03-23 US claimed
EP-1466214-A2 NEGATIVE-WORKING PHOTOIMABEABLE BOTTOM ANTIREFLECTIVE COATING AZ Electronic Materials USA Corp. (US) 2004-10-13 EP claimed
US-20030215736-A1 Negative-working photoimageable bottom antireflective coating AZ ELECTRONIC MATERIALS USA CORP. 2003-11-20 US claimed
WO-2003058345-A2 NEGATIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING CLARIANT INTERNATIONAL LTD (CH) 2003-07-17 WO claimed
US-8088548-B2 Bottom antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-01-03 US disclosed
EP-2212273-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2010-08-04 EP disclosed
US-7553905-B2 Anti-reflective coatings AZ ELECTRONIC MATERIALS USA CORP. (US) 2009-06-30 US disclosed
WO-2009053832-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2009-04-30 WO disclosed
US-20090104559-A1 Bottom Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2009-04-23 US disclosed
EP-1966255-A1 ANTI-REFLECTIVE COATINGS AZ Electronic Materials USA Corp. (US) 2008-09-10 EP disclosed
WO-2007052132-A1 ANTI-REFLECTIVE COATINGS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2007-05-10 WO disclosed
US-20070099108-A1 Anti-reflective coatings MERCK PATENT GMBH (DE) 2007-05-03 US disclosed
US-20060063105-A1 Negative-working photoimageable bottom antireflective coating OBERLANDER JOSEPH E 2006-03-23 US disclosed
EP-1466214-A2 NEGATIVE-WORKING PHOTOIMABEABLE BOTTOM ANTIREFLECTIVE COATING AZ Electronic Materials USA Corp. (US) 2004-10-13 EP disclosed
US-20030215736-A1 Negative-working photoimageable bottom antireflective coating AZ ELECTRONIC MATERIALS USA CORP. 2003-11-20 US disclosed
WO-2003058345-A2 NEGATIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING CLARIANT INTERNATIONAL LTD (CH) 2003-07-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104559-A1 Bottom Antireflective Coating Compositions SDC2, S100A9, MYH9 RAB9A 171/4885NPC1 369/4885SMN1; SMN2 579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.