SCHEMBL21798715

SCHEMBL21798715

Fc1ccc(-c2ccccc2I)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR4A2 P43354 1/20 0.52
▸ PTGS2 P35354 3/20 0.47
▸ PTGS1 P23219 1/20 0.47
▸ SLC6A4 P31645 1/20 0.43
▸ SLC6A3 Q01959 1/20 0.43
▸ HTR7 P34969 1/20 0.42
▸ CASP3 P42574 2/20 0.41
▸ SENP8 Q96LD8 2/20 0.41
▸ SENP7 Q9BQF6 2/20 0.41
▸ SENP6 Q9GZR1 2/20 0.41
▸ MAPK14 Q16539 6/20 0.41
▸ GCGR P47871 2/20 0.41
▸ HTR2C P28335 1/20 0.40
▸ ALDH1A3 P47895 1/20 0.38
▸ NPC1 O15118 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ MAOB P27338 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL1805194 0.82 PTGS2 (0.46) NR4A2PTGS2PTGS1SLC6A4SLC6A3
SCHEMBL9807036 0.80 ALDH1A1 (0.33) NR4A2PTGS2CASP3SENP8SENP7
SCHEMBL6830189 0.80 ALDH1A1 (0.47) PTGS2CASP3SENP8SENP7SENP6
SCHEMBL30451343 0.79 ALDH1A1 (0.48) PTGS2CASP3SENP8SENP7SENP6
SCHEMBL154146 0.79 ALDH1A1 (0.48) PTGS2CASP3SENP8SENP7SENP6
SCHEMBL10304866 0.79 PTGS2 (0.42) NR4A2PTGS2PTGS1SLC6A4SLC6A3
SCHEMBL7154758 0.78 ALDH1A1 (0.42) PTGS2CASP3SENP8SENP7SENP6
SCHEMBL27649740 0.77 PTGS2 (0.57) NR4A2PTGS2PTGS1SLC6A4SLC6A3
SCHEMBL15484734 0.77 ALDH1A1 (0.46) PTGS2CASP3SENP8SENP7SENP6
Phosphine SCHEMBL28589614 0.77 ALDH1A1 (0.46) PTGS2CASP3SENP8SENP7SENP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12585186-B2 Photoacid generator, chemically amplified resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-03-24 — — US disclosed
US-20230384677-A1 ONIUM SALT COMPOUND, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-30 — — US disclosed
US-20230123180-A1 PHOTOACID GENERATOR, CHEMICALLY AMPLIFIED RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-04-20 — — US disclosed
US-11579526-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-02-14 — — US disclosed
US-11448961-B2 Iodonium salt, resist composition, and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-09-20 — — US disclosed
US-20200301274-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-09-24 — — US disclosed
US-20200102271-A1 ONIUM SALT, RESIST COMPOSITION, AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-04-02 — — US disclosed
US-20200081341-A1 IODONIUM SALT, RESIST COMPOSITION, AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-03-12 — — US disclosed
CN-101959908-A Radiation-sensitive composition, polymer and monomer JSR CORP 2011-01-26 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12585186-B2 Photoacid generator, chemically amplified resist composition, and patterning process LBR, LIFR, LEF1 NR4A2 1733/4885PTGS2 4130/4885PTGS1 3423/4885
US-20230384677-A1 ONIUM SALT COMPOUND, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS INSR, INSRR, SLC6A5 NR4A2 2887/4885PTGS2 4322/4885PTGS1 4197/4885
US-20200102271-A1 ONIUM SALT, RESIST COMPOSITION, AND PATTERN FORMING PROCESS C1R, NHERF1, INSR NR4A2 3505/4885PTGS2 4168/4885PTGS1 3893/4885
US-20200081341-A1 IODONIUM SALT, RESIST COMPOSITION, AND PATTERN FORMING PROCESS ETV6, ELOVL5, EEF2 NR4A2 3530/4885PTGS2 4030/4885PTGS1 4097/4885
US-11448961-B2 Iodonium salt, resist composition, and pattern forming process ETV6, ELOVL5, EEF2 NR4A2 3530/4885PTGS2 4030/4885PTGS1 4097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback