Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17366254 | 0.80 | MCHR1 (0.48) | L3MBTL1ALDH1A1PPARGPPARAGAA | |
| SCHEMBL20729405 | 0.74 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1PPARGPPARAGAA | |
| SCHEMBL7507747 | 0.73 | PPARG (0.66) | ALDH1A1PPARGPPARAGAALMNA | |
| SCHEMBL10361493 | 0.72 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1PPARGPPARAGAA | |
| SCHEMBL9060740 | 0.72 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1PPARGPPARAGAA | |
| SCHEMBL9060171 | 0.72 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1PPARGPPARAGAA | |
| SCHEMBL17366266 | 0.72 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1PPARGPPARAGAA | |
| SCHEMBL27538708 | 0.71 | PPARG (0.51) | L3MBTL1ALDH1A1PPARGPPARAGAA | |
| SCHEMBL28470780 | 0.70 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1PPARGPPARAGAA | |
| SCHEMBL27290749 | 0.70 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1PPARGPPARAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7981875-B2 | Treating pancreatic cancer by administering cardenolide uscharin extracted from Calotropis procera plants | UNIBIOSCREEN S.A. (BE) | 2011-07-19 | — | — | US | disclosed |
| WO-2009033505-A1 | HELLEBRIN DERIVATIVES | UNIBIOSCREEN S.A. (BE) | 2009-03-19 | — | — | WO | disclosed |
| US-20080261935-A1 | 2\" OXO-VORUSCHARIN AND DERIVATIVES THEREOF | UNIBIOSCREEN S.A. (BE) | 2008-10-23 | — | — | US | disclosed |
| EP-1709063-B1 | GLYCOSYLATED STEROID DERIVATIVES WITH ANTI-MIGRATORY ACTIVITY | UNIBIOSCREEN SA (BE) | 2008-01-23 | — | — | EP | disclosed |
| US-7320971-B2 | 2″ oxo-voruscharin and derivatives thereof | UNIBIOSCREEN S.A. (BE) | 2008-01-22 | — | — | US | disclosed |
| US-20070123473-A1 | Glycosylated steroid derivatives with anti-migratory activity | UNIBIOSCREEN S.A. (BE) | 2007-05-31 | — | — | US | disclosed |
| EP-1709063-A2 | GLYCOSYLATED STEROID DERIVATIVES WITH ANTI-MIGRATORY ACTIVITY | Unibioscreen S.A. (BE) | 2006-10-11 | — | — | EP | disclosed |
| US-20060166952-A1 | 2\"oxo-voruscharin and derivatives thereof | UNIVERSITE LIBRE DE BRUXELLES (BE) | 2006-07-27 | — | — | US | disclosed |
| US-20060149045-A1 | Steroid compounds with anti-tumor activity | UNIBIOSCREEN S.A. (BE) | 2006-07-06 | — | — | US | disclosed |
| EP-1551850-B1 | 2\" OXO-VORUSCHARIN AND DERIVATIVES THEREOF | UNIBIOSCREEN SA (BE) | 2006-05-24 | — | — | EP | disclosed |
| EP-1551850-A1 | 2\" OXO-VORUSCHARIN AND DERIVATIVES THEREOF | Unibioscreen S.A. (BE) | 2005-07-13 | — | — | EP | disclosed |
| WO-2005058934-A2 | GLYCOSYLATED STEROID DERIVATIVES WITH ANTI-MIGRATORY ACTIVITY | UNIBIOSCREEN S.A. (BE) | 2005-06-30 | — | — | WO | disclosed |
| US-20050119338-A1 | Combination of cytochome p450 dependent protease inhibitors | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-02 | — | — | US | disclosed |
| EP-1458447-A2 | COMBINATION OF CYTOCHOME P 450 DEPENDENT PROTEASE INHIBITORS | Tibotec Pharmaceuticals Ltd. (IE) | 2004-09-22 | — | — | EP | disclosed |
| WO-2004076433-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | disclosed |
| WO-2004076434-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | disclosed |
| WO-2004055039-A1 | STEROID COMPOUNDS WITH ANTI-TUMOR ACTIVITY | UNIBIOSCREEN S.A. (BE) | 2004-07-01 | — | — | WO | disclosed |
| WO-2004033465-A1 | 2' OXO-VORUSCHARIN AND DERIVATIVES THEREOF | UNIBIOSCREEN S.A. (BE) | 2004-04-22 | — | — | WO | disclosed |
| EP-1408043-A1 | 2''oxo-voruscharin and analogues thereof | Unibioscreen S.A. (BE) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003049746-A2 | COMBINATION OF CYTOCHOME P450 DEPENDENT PROTEASE INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2003-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261935-A1 | 2\" OXO-VORUSCHARIN AND DERIVATIVES THEREOF | RNASE1, FUT6, VNN1 | L3MBTL1 3320/4885ALDH1A1 1882/4885PPARG 4401/4885 |
| US-20070123473-A1 | Glycosylated steroid derivatives with anti-migratory activity | NR5A1, NR3C2, MIF | L3MBTL1 4485/4885ALDH1A1 1462/4885PPARG 927/4885 |
| US-20060149045-A1 | Steroid compounds with anti-tumor activity | CYP17A1, HSD17B7, NR5A1 | L3MBTL1 4883/4885ALDH1A1 1197/4885PPARG 444/4885 |
| US-20050119338-A1 | Combination of cytochome p450 dependent protease inhibitors | CYP27A1, CYP11A1, PITRM1 | L3MBTL1 3412/4885ALDH1A1 1362/4885PPARG 3859/4885 |
| US-20060166952-A1 | 2\"oxo-voruscharin and derivatives thereof | VNN1, RPN2, FUT6 | L3MBTL1 3181/4885ALDH1A1 1101/4885PPARG 4598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.