SCHEMBL22802288

SCHEMBL22802288

O=S(=O)(c1ccc(Br)cc1)c1c[nH]c2ccc(Br)cc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.55
▸ MEN1 O00255 4/20 0.51
▸ KMT2A Q03164 4/20 0.51
▸ GPR84 Q9NQS5 1/20 0.47
▸ HDAC3 O15379 1/20 0.47
▸ HDAC4 P56524 1/20 0.47
▸ HDAC1 Q13547 1/20 0.47
▸ HDAC7 Q8WUI4 1/20 0.47
▸ HDAC2 Q92769 1/20 0.47
▸ HDAC10 Q969S8 1/20 0.47
▸ HDAC11 Q96DB2 1/20 0.47
▸ HDAC8 Q9BY41 1/20 0.47
▸ HDAC6 Q9UBN7 1/20 0.47
▸ HDAC9 Q9UKV0 1/20 0.47
▸ HDAC5 Q9UQL6 1/20 0.47
▸ POLB P06746 2/20 0.47
▸ DUSP3 P51452 1/20 0.47
▸ PTPN5 P54829 1/20 0.47
▸ PTPN11 Q06124 1/20 0.47
▸ SMN1; SMN2 Q16637 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5971987 0.91 MEN1 (0.59) MAPTMEN1KMT2AGPR84HDAC3
SCHEMBL3566797 0.91 HDAC3 (0.57) MAPTMEN1KMT2AGPR84HDAC3
SCHEMBL5971960 0.82 HTR6 (0.50) MAPTHDAC3HDAC4HDAC1HDAC7
SCHEMBL30091335 0.82 LMNA (0.49) MAPTMEN1KMT2AGPR84HDAC3
SCHEMBL30091143 0.80 MET (0.58) MAPTMEN1KMT2AHDAC3HDAC4
SCHEMBL28920451 0.80 MET (0.58) MAPTMEN1KMT2AHDAC3HDAC4
SCHEMBL18591261 0.80 GPR84 (0.50) MAPTMEN1KMT2AGPR84NR4A2
SCHEMBL18555016 0.80 GPR84 (0.50) MAPTMEN1KMT2AGPR84CA12
SCHEMBL22158064 0.79 FEN1 (0.44) MAPTGPR84HDAC3HDAC4HDAC1
SCHEMBL3574514 0.78 HDAC3 (0.48) MAPTMEN1KMT2AHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12202798-B2 Antimicrobial compounds, compositions, and articles of manufacture for selectively inhibiting pathogenic microbes CFD RESEARCH CORPORATION (US) 2025-01-21 — — US claimed
US-11180452-B2 Methods and compositions for selectively inhibiting pathogenic microbes CFD RESEARCH CORPORATION (US) 2021-11-23 — — US claimed
US-20200399218-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND ARTICLES OF MANUFACTURE FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RESEARCH CORPORATION 2020-12-24 — — US claimed
US-20200399217-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RESEARCH CORPORATION 2020-12-24 — — US claimed
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 — — US disclosed
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 — — US disclosed
US-12202798-B2 Antimicrobial compounds, compositions, and articles of manufacture for selectively inhibiting pathogenic microbes CFD RESEARCH CORPORATION (US) 2025-01-21 — — US disclosed
US-11180452-B2 Methods and compositions for selectively inhibiting pathogenic microbes CFD RESEARCH CORPORATION (US) 2021-11-23 — — US disclosed
US-11180452-B2 Methods and compositions for selectively inhibiting pathogenic microbes CFD RESEARCH CORPORATION (US) 2021-11-23 — — US disclosed
US-20200399218-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND ARTICLES OF MANUFACTURE FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RESEARCH CORPORATION 2020-12-24 — — US disclosed
US-20200399218-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND ARTICLES OF MANUFACTURE FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RESEARCH CORPORATION 2020-12-24 — — US disclosed
US-20200399217-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RESEARCH CORPORATION 2020-12-24 — — US disclosed
US-20200399217-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RESEARCH CORPORATION 2020-12-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12202798-B2 Antimicrobial compounds, compositions, and articles of manufacture for selectively inhibiting pathogenic microbes ZYX, IDO1, CRY1 MAPT 272/4885MEN1 1296/4885KMT2A 2903/4885
US-11180452-B2 Methods and compositions for selectively inhibiting pathogenic microbes FPR1, FPR3, ARG1 MAPT 1240/4885MEN1 1299/4885KMT2A 3060/4885
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 MAPT 48/4885MEN1 2402/4885KMT2A 4633/4885
US-20200399217-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES FPR1, FPR3, ARG1 MAPT 1240/4885MEN1 1299/4885KMT2A 3060/4885
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 MAPT 48/4885MEN1 2402/4885KMT2A 4633/4885
US-20200399218-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND ARTICLES OF MANUFACTURE FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES ZYX, IDO1, CRY1 MAPT 272/4885MEN1 1296/4885KMT2A 2903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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