Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | BHMT | Q93088 | 2/20 | 0.33 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114588 | 0.96 | CTSL (0.42) | CTSLCTSBGBA1ROCK2BHMT | |
| SCHEMBL12790596 | 0.93 | CTSL (0.40) | CTSLCTSBGBA1ROCK2BHMT | |
| SCHEMBL12353650 | 0.84 | LMNA (0.41) | CTSLCTSBGBA1ROCK2BHMT | |
| SCHEMBL1705186 | 0.84 | — | — | |
| SCHEMBL8991438 | 0.84 | — | — | |
| SCHEMBL7964479 | 0.82 | — | — | |
| SCHEMBL1402574 | 0.82 | — | — | |
| SCHEMBL12396066 | 0.82 | CTSL (0.34) | CTSLCTSBGBA1ROCK2BHMT | |
| SCHEMBL22338482 | 0.82 | — | — | |
| SCHEMBL19300210 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854923-A | Boron-containing tackifier for silicone rubber and preparation method and application thereof | 中国科学院化学研究所 | 2023-10-10 | — | — | CN | claimed |
| EP-1899317-A2 | ENANTIOMERS OF N,N-DIMETHYL-3-(2-THIENYL)-3-HYDROXYPROPANAMINE BORANE AS INTERMEDIATES IN THE SYNTHESIS OF DULOXETINE | Teva Pharmaceutical Industries Ltd (IL) | 2008-03-19 | — | — | EP | claimed |
| US-20080015362-A1 | Process for the preparation of optically active (S)-(+)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine | TEVA PHARMACEUTICALS USA, INC. | 2008-01-17 | — | — | US | claimed |
| WO-2007123900-A2 | ENANTIOMERS OF N,N-DIMETHYL-3-(2-THIENYL)-3-HYDROXYPROPANAMINE BORANE AS INTERMEDIATES IN THE SYNTHESIS OF DULOXETINE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-11-01 | — | — | WO | claimed |
| US-20060069263-A1 | Process for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzo-thiazole | CHEMAGIS LTD. (IL) | 2006-03-30 | — | — | US | claimed |
| US-5567849-A | Borane-sulfide hydroboration agents | ALDRICH CHEMICAL COMPANY, INC. (US) | 1996-10-22 | — | — | US | claimed |
| CN-116855223-A | High-bonding-strength organic silicon bonding sealant and preparation method and application thereof | 中国科学院化学研究所 | 2023-10-10 | — | — | CN | disclosed |
| CN-116854923-A | Boron-containing tackifier for silicone rubber and preparation method and application thereof | 中国科学院化学研究所 | 2023-10-10 | — | — | CN | disclosed |
| US-11008290-B2 | Halogenated quinoline derivatives as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-05-18 | — | — | US | disclosed |
| US-10736966-B2 | Brush-poly (glycoamidoamine)-lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-08-11 | — | — | US | disclosed |
| US-20180265475-A1 | HALOGENATED QUINOLINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-09-20 | — | — | US | disclosed |
| US-9840479-B2 | Polyamine-fatty acid derived lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-12-12 | — | — | US | disclosed |
| EP-3164379-A1 | POLYAMINE-FATTY ACID DERIVED LIPIDOIDS AND USES THEREOF | Massachusetts Institute of Technology (US) | 2017-05-10 | — | — | EP | disclosed |
| WO-2007123900-A2 | ENANTIOMERS OF N,N-DIMETHYL-3-(2-THIENYL)-3-HYDROXYPROPANAMINE BORANE AS INTERMEDIATES IN THE SYNTHESIS OF DULOXETINE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007011065-A2 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-01-25 | — | — | WO | disclosed |
| WO-2006116007-A2 | METHODS FOR SYNTHESIS OF DICARBAMATE COMPOUNDS AND INTERMEDIATES IN THE FORMATION THEREOF | MEDPOINTE HEALTHCARE INC. (US) | 2006-11-02 | — | — | WO | disclosed |
| US-20060241298-A1 | Methods for synthesis of dicarbamate compounds and intermediates in the formation thereof | MEDPOINTE HEALTHCARE INC. | 2006-10-26 | — | — | US | disclosed |
| US-20060069263-A1 | Process for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzo-thiazole | CHEMAGIS LTD. (IL) | 2006-03-30 | — | — | US | disclosed |
| US-6204405-B1 | REACTING TRI-O-PHENYLENE BIS BORATE WITH DIBORANE | SIGMA-ALDRICH CO. | 2001-03-20 | — | — | US | disclosed |
| US-5567849-A | Borane-sulfide hydroboration agents | ALDRICH CHEMICAL COMPANY, INC. (US) | 1996-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015362-A1 | Process for the preparation of optically active (S)-(+)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine | HTR3A, PNMT, TPH1 | CTSL 2748/4885CTSB 2362/4885GBA1 683/4885 |
| US-10736966-B2 | Brush-poly (glycoamidoamine)-lipids and uses thereof | GLUL, GLS, FPGS | CTSL 153/4885CTSB 1297/4885GBA1 45/4885 |
| US-20060069263-A1 | Process for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzo-thiazole | TST, ABAT, TH | CTSL 1908/4885CTSB 3346/4885GBA1 830/4885 |
| US-20180265475-A1 | HALOGENATED QUINOLINE DERIVATIVES AS ANTIMICROBIAL AGENTS | NDUFS5, NDUFS7, NDUFS3 | CTSL 1545/4885CTSB 1073/4885GBA1 1348/4885 |
| US-11008290-B2 | Halogenated quinoline derivatives as antimicrobial agents | NDUFS5, NDUFS7, NDUFS3 | CTSL 1545/4885CTSB 1073/4885GBA1 1348/4885 |
| US-20060241298-A1 | Methods for synthesis of dicarbamate compounds and intermediates in the formation thereof | CPS1, ME1, TALDO1 | CTSL 1431/4885CTSB 378/4885GBA1 845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.