SCHEMBL2298657

SCHEMBL2298657

O=C(c1ccccc1)c1ccccc1OCCCCCCCCO

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.58
DRD1 P21728 1/20 0.58
DRD3 P35462 1/20 0.58
CNR2 P34972 3/20 0.52
LMNA P02545 4/20 0.50
MAPT P10636 3/20 0.50
KMT2A Q03164 2/20 0.50
CNR1 P21554 2/20 0.50
MEN1 O00255 1/20 0.50
NR1I2 O75469 1/20 0.50
CHRM2 P08172 1/20 0.50
CYP3A4 P08684 1/20 0.50
ADRA2A P08913 1/20 0.50
OPRK1 P41145 1/20 0.50
HTR2B P41595 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
ABCB1 P08183 6/20 0.49
ALDH1A1 P00352 2/20 0.49
PTK2B Q14289 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22361798 1.00 DRD2 (0.58) DRD2DRD1DRD3CNR2LMNA
SCHEMBL22361799 1.00 DRD2 (0.58) DRD2DRD1DRD3CNR2LMNA
SCHEMBL29548720 1.00 DRD2 (0.58) DRD2DRD1DRD3CNR2LMNA
SCHEMBL4662846 1.00 DRD2 (0.58) DRD2DRD1DRD3CNR2LMNA
SCHEMBL28881630 0.98 DRD2 (0.59) DRD2DRD1DRD3CNR2LMNA
SCHEMBL2228867 0.89 DRD2 (0.62) DRD2DRD1DRD3LMNAMAPT
SCHEMBL2469614 0.86 LMNA (0.68) DRD2DRD1DRD3CNR2LMNA
SCHEMBL6433586 0.86 LMNA (0.68) DRD2DRD1DRD3CNR2LMNA
SCHEMBL11216088 0.86 LMNA (0.68) DRD2DRD1DRD3CNR2LMNA
SCHEMBL536375 0.86 LMNA (0.68) DRD2DRD1DRD3CNR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12414977-B2 Method of administering seaberry and saw palmetto extracts to inhibit 5α-reductase activity ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2025-09-16 US disclosed
US-20250268972-A1 5a-REDUCTASE INHIBITOR ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2025-08-28 US disclosed
WO-2025110244-A1 NOVEL COMPOUND AND USE THEREOF オリザ油化株式会社 2025-05-30 WO disclosed
US-12221495-B2 Cyclic peptide and a medicament, external preparation and cosmetic comprising said cyclic peptide IGISU CO., LTD. (JP) 2025-02-11 US disclosed
US-12065512-B2 Cyclic peptide and a medicament, external preparation and cosmetic comprising said cyclic peptide IGISU CO., LTD. (JP) 2024-08-20 US disclosed
US-20230190854-A1 METHOD OF REDUCING MUSCLE DAMAGE ASSOCIATED WITH INTENSIVE EXERCISE BY ADMINISTERING PURPLE-TEA EXTRACT ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2023-06-22 US disclosed
US-20220370539-A1 5a-REDUCTASE INHIBITOR ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2022-11-24 US disclosed
US-11478495-B2 AMPK activating agent ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2022-10-25 US disclosed
EP-4014987-A2 CYCLIC PEPTIDE, AND MEDICINE, EXTERNAL PREPARATION AND COSMETIC EACH CONTAINING SAID CYCLIC PEPTIDE Igisu Co., Ltd. (JP) 2022-06-22 EP disclosed
EP-2765145-B1 SILYLATED POLYBUTADIENE NIPPON SODA CO (JP) 2022-03-02 EP disclosed
US-20070154575-A1 Anti-inflammatory agent ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2007-07-05 US disclosed
US-20070141000-A1 STABILIZED ASCORBIC ACID DERIVATIVE SHOWA DENKO K.K. 2007-06-21 US disclosed
US-7232857-B2 Radiation hardenable adhesive composition containing dispersed natural rubber fine particles TOPPAN FORMS CO., LTD. (JP) 2007-06-19 US disclosed
US-7223775-B2 Stabilized ascorbic acid derivatives SHOWA DENKO K.K. (JP) 2007-05-29 US disclosed
EP-1674106-A1 DIETETIC COMPOSITION Oryza Oil & Fat Chemical Co., Ltd (JP) 2006-06-28 EP disclosed
US-20060100177-A1 Stabilized ascorbic acid derivatives SHOWA DENKO K.K. (JP) 2006-05-11 US disclosed
EP-1496889-B1 STABILIZED ASCORBIC ACID DERIVATIVES SHOWA DENKO KK (JP) 2005-08-17 EP disclosed
US-20050080181-A1 Radiation hardenable adhesive composition containing dispersed natural rubber fine particles TOPPAN FORMS CO., LTD. (JP) 2005-04-14 US disclosed
EP-1496889-A1 STABILIZED ASCORBIC ACID DERIVATIVES Showa Denko K.K. (JP) 2005-01-19 EP disclosed
WO-2003086384-A1 STABILIZED ASCORBIC ACID DERIVATIVES SHOWA DENKO K. K. (JP) 2003-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060100177-A1 Stabilized ascorbic acid derivatives RBP1, SOD1, PROC DRD2 2148/4885DRD1 1083/4885DRD3 2362/4885
US-20230190854-A1 METHOD OF REDUCING MUSCLE DAMAGE ASSOCIATED WITH INTENSIVE EXERCISE BY ADMINISTERING PURPLE-TEA EXTRACT PYGM, MUSK, GCK DRD2 2765/4885DRD1 2557/4885DRD3 2780/4885
US-20070154575-A1 Anti-inflammatory agent TNF, IL18, CD14 DRD2 2094/4885DRD1 1584/4885DRD3 1457/4885
US-12221495-B2 Cyclic peptide and a medicament, external preparation and cosmetic comprising said cyclic peptide TSLP, NPR1, VIP DRD2 3809/4885DRD1 2929/4885DRD3 2894/4885
US-11478495-B2 AMPK activating agent PRKAG2, PRKAG1, PRKAG3 DRD2 2845/4885DRD1 2861/4885DRD3 3896/4885
US-12065512-B2 Cyclic peptide and a medicament, external preparation and cosmetic comprising said cyclic peptide TSLP, NPR1, VIP DRD2 3809/4885DRD1 2929/4885DRD3 2894/4885
US-20070141000-A1 STABILIZED ASCORBIC ACID DERIVATIVE SOD1, PROC, RBP1 DRD2 2137/4885DRD1 1202/4885DRD3 2357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.