SCHEMBL2298660

SCHEMBL2298660

CCCCCCCC(O)Oc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 6/20 0.51
ALDH1A1 P00352 2/20 0.46
ELANE P08246 1/20 0.45
PRSS1 P07477 2/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
LMNA P02545 2/20 0.44
KDM4E B2RXH2 1/20 0.44
RECQL P46063 1/20 0.44
NR1I2 O75469 1/20 0.44
CHRM2 P08172 1/20 0.44
CYP3A4 P08684 1/20 0.44
ADRA2A P08913 1/20 0.44
MAPT P10636 1/20 0.44
OPRK1 P41145 1/20 0.44
HTR2B P41595 1/20 0.44
SLC6A3 Q01959 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4662850 1.00 ABCB1 (0.51) ABCB1ALDH1A1ELANEPRSS1PRSS2
SCHEMBL28942957 0.87 ABCB1 (0.41) ABCB1ALDH1A1ELANEPRSS1PRSS2
SCHEMBL3830542 0.87 ALDH1A1 (0.55) ABCB1ALDH1A1ELANEPRSS1PRSS2
SCHEMBL8211136 0.86 KDM4E (0.58) ALDH1A1PRSS1PRSS2PRSS3MEN1
SCHEMBL27616829 0.86 ALDH1A1 (0.48) ABCB1ALDH1A1ELANEPRSS1PRSS2
SCHEMBL27654699 0.86 ABCB1 (0.47) ABCB1ALDH1A1ELANEPRSS1PRSS2
Bromide SCHEMBL15796925 0.85 ABCB1 (0.46) ABCB1ALDH1A1ELANEPRSS1PRSS2
Iodide SCHEMBL15796938 0.85 ABCB1 (0.46) ABCB1ALDH1A1ELANEPRSS1PRSS2
Hydrochloric Acid SCHEMBL15796915 0.85 ABCB1 (0.46) ABCB1ALDH1A1ELANEPRSS1PRSS2
SCHEMBL2048117 0.82 ABCB1 (0.68) ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12414977-B2 Method of administering seaberry and saw palmetto extracts to inhibit 5α-reductase activity ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2025-09-16 US disclosed
US-20250268972-A1 5a-REDUCTASE INHIBITOR ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2025-08-28 US disclosed
WO-2025110244-A1 NOVEL COMPOUND AND USE THEREOF オリザ油化株式会社 2025-05-30 WO disclosed
US-12221495-B2 Cyclic peptide and a medicament, external preparation and cosmetic comprising said cyclic peptide IGISU CO., LTD. (JP) 2025-02-11 US disclosed
US-20240376153-A1 CNP CYCLIC PEPTIDE, AND MEDICINE, EXTERNAL PREPARATION AND COSMETIC EACH CONTAINING SAID CYCLIC PEPTIDE IGISU CO., LTD. (JP) 2024-11-14 US disclosed
US-12065512-B2 Cyclic peptide and a medicament, external preparation and cosmetic comprising said cyclic peptide IGISU CO., LTD. (JP) 2024-08-20 US disclosed
US-20230190854-A1 METHOD OF REDUCING MUSCLE DAMAGE ASSOCIATED WITH INTENSIVE EXERCISE BY ADMINISTERING PURPLE-TEA EXTRACT ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2023-06-22 US disclosed
US-20220370539-A1 5a-REDUCTASE INHIBITOR ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2022-11-24 US disclosed
US-11478495-B2 AMPK activating agent ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2022-10-25 US disclosed
EP-4014987-A2 CYCLIC PEPTIDE, AND MEDICINE, EXTERNAL PREPARATION AND COSMETIC EACH CONTAINING SAID CYCLIC PEPTIDE Igisu Co., Ltd. (JP) 2022-06-22 EP disclosed
US-20070154575-A1 Anti-inflammatory agent ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2007-07-05 US disclosed
US-20070141000-A1 STABILIZED ASCORBIC ACID DERIVATIVE SHOWA DENKO K.K. 2007-06-21 US disclosed
US-7232857-B2 Radiation hardenable adhesive composition containing dispersed natural rubber fine particles TOPPAN FORMS CO., LTD. (JP) 2007-06-19 US disclosed
US-7223775-B2 Stabilized ascorbic acid derivatives SHOWA DENKO K.K. (JP) 2007-05-29 US disclosed
EP-1674106-A1 DIETETIC COMPOSITION Oryza Oil & Fat Chemical Co., Ltd (JP) 2006-06-28 EP disclosed
US-20060100177-A1 Stabilized ascorbic acid derivatives SHOWA DENKO K.K. (JP) 2006-05-11 US disclosed
EP-1496889-B1 STABILIZED ASCORBIC ACID DERIVATIVES SHOWA DENKO KK (JP) 2005-08-17 EP disclosed
US-20050080181-A1 Radiation hardenable adhesive composition containing dispersed natural rubber fine particles TOPPAN FORMS CO., LTD. (JP) 2005-04-14 US disclosed
EP-1496889-A1 STABILIZED ASCORBIC ACID DERIVATIVES Showa Denko K.K. (JP) 2005-01-19 EP disclosed
WO-2003086384-A1 STABILIZED ASCORBIC ACID DERIVATIVES SHOWA DENKO K. K. (JP) 2003-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060100177-A1 Stabilized ascorbic acid derivatives RBP1, SOD1, PROC ABCB1 3765/4885ALDH1A1 4/4885ELANE 3926/4885
US-20230190854-A1 METHOD OF REDUCING MUSCLE DAMAGE ASSOCIATED WITH INTENSIVE EXERCISE BY ADMINISTERING PURPLE-TEA EXTRACT PYGM, MUSK, GCK ABCB1 4695/4885ALDH1A1 3457/4885ELANE 4050/4885
US-20070154575-A1 Anti-inflammatory agent TNF, IL18, CD14 ABCB1 1474/4885ALDH1A1 349/4885ELANE 380/4885
US-12221495-B2 Cyclic peptide and a medicament, external preparation and cosmetic comprising said cyclic peptide TSLP, NPR1, VIP ABCB1 3903/4885ALDH1A1 4260/4885ELANE 2286/4885
US-20240376153-A1 CNP CYCLIC PEPTIDE, AND MEDICINE, EXTERNAL PREPARATION AND COSMETIC EACH CONTAINING SAID CYCLIC PEPTIDE NPR1, CNP, NPR3 ABCB1 3988/4885ALDH1A1 4500/4885ELANE 918/4885
US-11478495-B2 AMPK activating agent PRKAG2, PRKAG1, PRKAG3 ABCB1 4659/4885ALDH1A1 2058/4885ELANE 4436/4885
US-12065512-B2 Cyclic peptide and a medicament, external preparation and cosmetic comprising said cyclic peptide TSLP, NPR1, VIP ABCB1 3903/4885ALDH1A1 4260/4885ELANE 2286/4885
US-20070141000-A1 STABILIZED ASCORBIC ACID DERIVATIVE SOD1, PROC, RBP1 ABCB1 4125/4885ALDH1A1 37/4885ELANE 3131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.