Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.89 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.41 |
| ▸ | PLEC | Q15149 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.38 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.37 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2304007 | 1.00 | THRB (0.89) | THRBUSP2PTPN1ATML3MBTL1 | |
| SCHEMBL29833902 | 0.94 | THRB (1.00) | THRBUSP2PTPN1ATML3MBTL1 | |
| SCHEMBL2304009 | 0.94 | THRB (1.00) | THRBUSP2PTPN1ATML3MBTL1 | |
| SCHEMBL109532 | 0.94 | THRB (1.00) | THRBUSP2PTPN1ATML3MBTL1 | |
| SCHEMBL31122162 | 0.92 | THRB (0.75) | THRBENPP2MEN1KMT2APHLPP2 | |
| SCHEMBL12955080 | 0.92 | THRB (0.75) | THRBENPP2MEN1KMT2APHLPP2 | |
| SCHEMBL1755507 | 0.92 | THRB (0.75) | THRBENPP2MEN1KMT2APHLPP2 | |
| SCHEMBL2304017 | 0.91 | THRB (0.74) | THRBENPP2MEN1KMT2APHLPP2 | |
| SCHEMBL21221487 | 0.91 | THRB (0.74) | THRBENPP2MEN1KMT2APHLPP2 | |
| SCHEMBL11129981 | 0.88 | THRB (0.78) | THRBUSP2PTPN1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4750804-B2 | — | — | 2011-08-17 | — | — | JP | claimed |
| JP-2008531514-A | — | — | 2008-08-14 | — | — | JP | claimed |
| EP-1850664-A2 | PESTICIDAL CAPSULE FORMULATION | Syngeta Participations AG (CH) | 2007-11-07 | — | — | EP | claimed |
| WO-2006089747-A2 | PRESTICIDAL CAPSULE FORMULATION | SYNGENTA PARTICIPATIONS AG (CH) | 2006-08-31 | — | — | WO | claimed |
| US-20250367330-A1 | OPTICAL CLEARING ENABLED BY THE KRAMERS-KRONIG RELATION | UNIV LELAND STANFORD JUNIOR (US) | 2025-12-04 | — | — | US | disclosed |
| US-9204630-B2 | Capsule formulation | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-08 | — | — | US | disclosed |
| US-20100086603-A1 | COMPOSITION FOR PHOTOPROTECTION | SYNGENTA CROP PROTECTION, INC. (US) | 2010-04-08 | — | — | US | disclosed |
| EP-2068626-A2 | COMPOSITION FOR PHOTOPROTECTION | Syngenta Limited (GB) | 2009-06-17 | — | — | EP | disclosed |
| US-20080306026-A1 | Capsule Formulation | SYNGENTA CROP PROTECTION LLC | 2008-12-11 | — | — | US | disclosed |
| WO-2008032022-A2 | COMPOSITION FOR PHOTOPROTECTION | SYNGENTA LIMITED (GB) | 2008-03-20 | — | — | WO | disclosed |
| EP-1850664-A2 | PESTICIDAL CAPSULE FORMULATION | Syngeta Participations AG (CH) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006089747-A2 | PRESTICIDAL CAPSULE FORMULATION | SYNGENTA PARTICIPATIONS AG (CH) | 2006-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250367330-A1 | OPTICAL CLEARING ENABLED BY THE KRAMERS-KRONIG RELATION | TNNC1, GYS1, MUSK | THRB 4429/4885CA2 1902/4885USP2 2601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.