Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.39 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192312 | 0.99 | MAPT (0.44) | MAPTTLR8FUT7KDM4EALDH1A1 | |
| SCHEMBL18140853 | 0.99 | MAPT (0.44) | MAPTTLR8FUT7KDM4EALDH1A1 | |
| SCHEMBL18141388 | 0.99 | MAPT (0.44) | MAPTTLR8FUT7KDM4EALDH1A1 | |
| SCHEMBL18139671 | 0.99 | MAPT (0.44) | MAPTTLR8FUT7KDM4EALDH1A1 | |
| SCHEMBL18141747 | 0.99 | MAPT (0.44) | MAPTTLR8FUT7KDM4EALDH1A1 | |
| SCHEMBL18141275 | 0.99 | MAPT (0.44) | MAPTTLR8FUT7KDM4EALDH1A1 | |
| SCHEMBL18141645 | 0.99 | MAPT (0.44) | MAPTTLR8FUT7KDM4EALDH1A1 | |
| SCHEMBL1109611 | 0.99 | MAPT (0.44) | MAPTTLR8FUT7KDM4EALDH1A1 | |
| SCHEMBL18139114 | 0.99 | MAPT (0.44) | MAPTTLR8FUT7KDM4EALDH1A1 | |
| SCHEMBL18139726 | 0.99 | MAPT (0.44) | MAPTTLR8FUT7KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11623972-B2 | Substituted catechol monomers, copolymers and methods for use | RHODIA OPERATIONS (FR) | 2023-04-11 | — | — | US | disclosed |
| US-11613597-B2 | Substituted catechol polymeric dispersants | RHODIA OPERATIONS (FR) | 2023-03-28 | — | — | US | disclosed |
| CN-109312009-B | Latex for improved water resistance without high performance surfactants | 罗地亚经营管理公司 | 2022-01-07 | — | — | CN | disclosed |
| EP-3844227-A1 | SUBSTITUTED CATECHOL POLYMERIC DISPERSANTS | RHODIA OPERATIONS (FR) | 2021-07-07 | — | — | EP | disclosed |
| EP-3844139-A1 | SUBSTITUTED CATECHOL MONOMERS, COPOLYMERS AND METHODS FOR USE | RHODIA OPERATIONS (FR) | 2021-07-07 | — | — | EP | disclosed |
| US-20200071441-A1 | SUBSTITUTED CATECHOL MONOMERS, COPOLYMERS AND METHODS FOR USE | RHODIA OPERATIONS (FR) | 2020-03-05 | — | — | US | disclosed |
| WO-2020047372-A1 | SUBSTITUTED CATECHOL MONOMERS, COPOLYMERS AND METHODS FOR USE | RHODIA OPERATIONS (FR) | 2020-03-05 | — | — | WO | disclosed |
| WO-2020047377-A1 | SUBSTITUTED CATECHOL POLYMERIC DISPERSANTS | RHODIA OPERATIONS (FR) | 2020-03-05 | — | — | WO | disclosed |
| US-20200071442-A1 | SUBSTITUTED CATECHOL POLYMERIC DISPERSANTS | RHODIA OPERATIONS (FR) | 2020-03-05 | — | — | US | disclosed |
| EP-3119819-B1 | TRI-SUBSTITUTED AROMATIC-CONTAINING MONOMERS, COPOLYMERS AND METHODS FOR USE | RHODIA OPERATIONS (FR) | 2020-01-29 | — | — | EP | disclosed |
| WO-2014100181-A1 | COMPOSITIONS WITH PH RESPONSIVE COPOLYMER CONTAINING MAEP AND/OR MAHP AND METHODS FOR USING SAME | RHODIA OPERATIONS (FR) | 2014-06-26 | — | — | WO | disclosed |
| US-20140178324-A1 | Compositions with pH Responsive Copolymer Containing MAEP and/or MAHP and Method for Using Same | RHODIA OPERATIONS (FR) | 2014-06-26 | — | — | US | disclosed |
| US-20140178325-A1 | Anti-Settling and Thickening Compositions and Methods for Using Same | RHODIA OPERATIONS (FR) | 2014-06-26 | — | — | US | disclosed |
| EP-2534205-A2 | RHEOLOGY MODIFIER COMPOSITIONS AND METHODS OF USE | Rhodia Operations (FR) | 2012-12-19 | — | — | EP | disclosed |
| EP-2534184-A1 | RHEOLOGY MODIFIER POLYMER | Rhodia Operations (FR) | 2012-12-19 | — | — | EP | disclosed |
| US-20110256085-A1 | RHEOLOGY MODIFIER COMPOSITIONS AND METHODS OF USE | RHODIA OPERATIONS (FR) | 2011-10-20 | — | — | US | disclosed |
| US-20110243873-A1 | Rheology modifier polymer | RHODIA OPERATIONS (FR) | 2011-10-06 | — | — | US | disclosed |
| US-20110223125-A1 | COMPOSITIONS WITH FREEZE THAW STABILITY | RHODIA OPERATIONS (FR) | 2011-09-15 | — | — | US | disclosed |
| WO-2011100665-A2 | RHEOLOGY MODIFIER COMPOSITIONS AND METHODS OF USE | RHODIA OPERATIONS (FR) | 2011-08-18 | — | — | WO | disclosed |
| WO-2011100071-A1 | RHEOLOGY MODIFIER POLYMER | RHODIA OPERATIONS (FR) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110223125-A1 | COMPOSITIONS WITH FREEZE THAW STABILITY | C9, PUF60, BCL2L10 | MAPT 73/4885TLR8 764/4885FUT7 370/4885 |
| US-20140178324-A1 | Compositions with pH Responsive Copolymer Containing MAEP and/or MAHP and Method for Using Same | PRUNE1, PHLPP1, PHLPP2 | MAPT 328/4885TLR8 2925/4885FUT7 1925/4885 |
| US-20140178325-A1 | Anti-Settling and Thickening Compositions and Methods for Using Same | GRN, CAPG, C5 | MAPT 1339/4885TLR8 4047/4885FUT7 596/4885 |
| US-20110256085-A1 | RHEOLOGY MODIFIER COMPOSITIONS AND METHODS OF USE | SFN, YWHAZ, DSG1 | MAPT 2593/4885TLR8 2805/4885FUT7 1896/4885 |
| US-20110243873-A1 | Rheology modifier polymer | C1R, PUF60, C9 | MAPT 424/4885TLR8 1203/4885FUT7 1325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.