Trolamine

Trolamine

SCHEMBL23698348

O=CC(=O)O.OCCN(CCO)CCO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
ALOX15 P16050 2/20 0.39
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 2/20 0.33
EYA2 O00167 1/20 0.33
APP P05067 1/20 0.33
ACE P12821 1/20 0.33
LMNA P02545 1/20 0.32
CHRM2 P08172 1/20 0.32
ADRA2A P08913 1/20 0.32
TSHR P16473 1/20 0.32
DRD1 P21728 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
CYP2C19 P33261 1/20 0.32
ADRA1A P35348 1/20 0.32
DRD3 P35462 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL5875419 0.83 TSHR (0.50) KDM4EALOX15MAPTSMN1; SMN2TDP1
Trolamine SCHEMBL14989224 0.83 TSHR (0.50) KDM4EALOX15MAPTSMN1; SMN2TDP1
Trolamine SCHEMBL5874734 0.83 TSHR (0.50) KDM4EALOX15MAPTSMN1; SMN2TDP1
Trolamine SCHEMBL6479985 0.83 TSHR (0.50) KDM4EALOX15MAPTSMN1; SMN2TDP1
Trolamine SCHEMBL4944913 0.83 TSHR (0.50) KDM4EALOX15MAPTSMN1; SMN2TDP1
Trolamine SCHEMBL30358483 0.83 TSHR (0.50) KDM4EALOX15MAPTSMN1; SMN2TDP1
Trolamine SCHEMBL4944905 0.83 TSHR (0.50) KDM4EALOX15MAPTSMN1; SMN2TDP1
Trolamine SCHEMBL2587854 0.82 ALOX15 (0.46) KDM4EALOX15MAPTSMN1; SMN2TDP1
Trolamine SCHEMBL5874273 0.82 ALOX15 (0.46) KDM4EALOX15MAPTSMN1; SMN2TDP1
Trolamine SCHEMBL28735231 0.82 ALOX15 (0.46) KDM4EALOX15MAPTSMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12435294-B2 Prevention of the oxidation of perfumery raw materials and food raw materials FIRMENICH SA (CH) 2025-10-07 US claimed
US-20230210735-A1 PREVENTION, REDUCTION, OR AMELIORATION OF OLD PERSON SMELL FIRMENICH SA (CH) 2023-07-06 US claimed
CN-115996696-A Prevention, reduction or improvement of odor of elderly people 弗门尼舍有限公司 2023-04-21 CN claimed
EP-4164587-A1 PREVENTION, REDUCTION, OR AMELIORATION OF OLD PERSON SMELL Firmenich SA (CH) 2023-04-19 EP claimed
US-20210395638-A1 PREVENTION OF THE OXIDATION OF PERFUMERY RAW MATERIALS AND FOOD RAW MATERIALS FIRMENICH SA (CH) 2021-12-23 US claimed
WO-2021250130-A1 PREVENTION, REDUCTION, OR AMELIORATION OF OLD PERSON SMELL FIRMENICH SA (CH) 2021-12-16 WO claimed
EP-3856358-A2 PREVENTION OF THE OXIDATION OF PERFUMERY RAW MATERIALS AND FOOD RAW MATERIALS Firmenich SA (CH) 2021-08-04 EP claimed
CN-113038928-A Preventing oxidation of flavor and food materials 弗门尼舍有限公司 2021-06-25 CN claimed
US-12435294-B2 Prevention of the oxidation of perfumery raw materials and food raw materials FIRMENICH SA (CH) 2025-10-07 US disclosed
US-20230210735-A1 PREVENTION, REDUCTION, OR AMELIORATION OF OLD PERSON SMELL FIRMENICH SA (CH) 2023-07-06 US disclosed
CN-115996696-A Prevention, reduction or improvement of odor of elderly people 弗门尼舍有限公司 2023-04-21 CN disclosed
EP-4164587-A1 PREVENTION, REDUCTION, OR AMELIORATION OF OLD PERSON SMELL Firmenich SA (CH) 2023-04-19 EP disclosed
US-20210395638-A1 PREVENTION OF THE OXIDATION OF PERFUMERY RAW MATERIALS AND FOOD RAW MATERIALS FIRMENICH SA (CH) 2021-12-23 US disclosed
WO-2021250130-A1 PREVENTION, REDUCTION, OR AMELIORATION OF OLD PERSON SMELL FIRMENICH SA (CH) 2021-12-16 WO disclosed
EP-3856358-A2 PREVENTION OF THE OXIDATION OF PERFUMERY RAW MATERIALS AND FOOD RAW MATERIALS Firmenich SA (CH) 2021-08-04 EP disclosed
CN-113038928-A Preventing oxidation of flavor and food materials 弗门尼舍有限公司 2021-06-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435294-B2 Prevention of the oxidation of perfumery raw materials and food raw materials CUTA, MPO, GPX4 KDM4E 4695/4885ALOX15 26/4885MAPT 3913/4885
US-20230210735-A1 PREVENTION, REDUCTION, OR AMELIORATION OF OLD PERSON SMELL ACHE, RBP4, LPO KDM4E 3481/4885ALOX15 990/4885MAPT 2985/4885
US-20210395638-A1 PREVENTION OF THE OXIDATION OF PERFUMERY RAW MATERIALS AND FOOD RAW MATERIALS CUTA, MPO, GPX4 KDM4E 4695/4885ALOX15 26/4885MAPT 3913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.