Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.46 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1525254 | 0.89 | ALDH1A1 (0.47) | ALDH1A1TDP1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL30872001 | 0.76 | ALDH1A1 (0.49) | ALDH1A1TDP1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL29216432 | 0.76 | ALDH1A1 (0.49) | ALDH1A1TDP1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL3651045 | 0.75 | TXNRD1 (0.42) | ALDH1A1TDP1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL28260841 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL28866740 | 0.71 | ACHE (0.45) | ALDH1A1TDP1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL9404818 | 0.68 | BCL2L1 (0.42) | ALDH1A1TDP1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL5542606 | 0.68 | PNMT (0.33) | NOS1PNMTNOS2 | |
| SCHEMBL1936960 | 0.68 | CYP1A2 (0.44) | ALDH1A1TDP1CYP3A4ACHEPOLB | |
| SCHEMBL5543201 | 0.68 | DRD2 (0.35) | NOS1MAPK10RIPK1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11531207-B2 | Devices, apparatus and method for providing photostimulation and imaging of structures | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-12-20 | — | — | US | disclosed |
| US-20180173004-A1 | DEVICES, APPARATUS AND METHOD FOR PROVIDING PHOTOSTIMULATION AND IMAGING OF STRUCTURES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2018-06-21 | — | — | US | disclosed |
| US-9846313-B2 | Devices, apparatus and method for providing photostimulation and imaging of structures | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-12-19 | — | — | US | disclosed |
| US-9625448-B2 | Double caged GABA compounds, bis-CNB-GABA | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2017-04-18 | — | — | US | disclosed |
| US-9161931-B2 | Dithiol compounds and treatment of presbyopia using said compounds | ENCORE HEALTH, LLC (US) | 2015-10-20 | — | — | US | disclosed |
| US-20150266809-A1 | DOUBLE CAGED GABA COMPOUNDS, BIS-CNB-GABA | THE TRUSTEES OF PRINCETON UNIVERSITY | 2015-09-24 | — | — | US | disclosed |
| US-20140243385-A1 | Dithiol Compounds, Derivatives, and Uses Therefor | ENCORE HEALTH, LLC (US) | 2014-08-28 | — | — | US | disclosed |
| US-8697109-B2 | Caged mercaptan and seleno-mercaptan compounds and methods of using them | ENCORE HEALTH, LLC (US) | 2014-04-15 | — | — | US | disclosed |
| US-8642785-B2 | Photolabile dinitroindolinyl based compounds | PHILADELPHIA HEALTH & EDUCATION CORPORATION (US) | 2014-02-04 | — | — | US | disclosed |
| US-20110233046-A1 | DEVICES, APPARATUS AND METHOD FOR PROVIDING PHOTOSTIMULATION AND IMAGING OF STRUCTURES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2011-09-29 | — | — | US | disclosed |
| US-4980096-A | Protective coatings; adhesives | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-12-25 | — | — | US | disclosed |
| US-4740600-A | UNBLOCKING WITH ACTINIC RADIATION; PROTECTIVE COATING; THERMOPLASTIC RESIN MIXTURES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-04-26 | — | — | US | disclosed |
| US-4599273-A | PROTECTIVE COATINGS, PRESSURE SENSITIVE ADHESIVES | MINNESOTA MINING AND MANUFACTURING CO. (US) | 1986-07-08 | — | — | US | disclosed |
| EP-0046028-B1 | IMAGING PROCESS AND ARTICLE EMPLOYING PHOTOLABILE, BLOCKED SURFACTANT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-05-07 | — | — | EP | disclosed |
| EP-0046083-B1 | PHOTOLABILE BLOCKED SURFACTANTS AND COMPOSITIONS CONTAINING THE SAME | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-10-16 | — | — | EP | disclosed |
| US-4478967-A | Photolabile blocked surfactants and compositions containing the same | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-10-23 | — | — | US | disclosed |
| US-4467022-A | Imaging process and article employing photolabile, blocked surfactant | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-08-21 | — | — | US | disclosed |
| US-4369244-A | ACTINIC RADIATION FILM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-01-18 | — | — | US | disclosed |
| EP-0046028-A2 | Imaging process and article employing photolabile, blocked surfactant | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-02-17 | — | — | EP | disclosed |
| EP-0046083-A2 | Photolabile blocked surfactants and compositions containing the same | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-02-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266809-A1 | DOUBLE CAGED GABA COMPOUNDS, BIS-CNB-GABA | GABRB2, GABRB3, GABRB1 | ALDH1A1 2034/4885TDP1 2962/4885CYP3A4 1630/4885 |
| US-20140243385-A1 | Dithiol Compounds, Derivatives, and Uses Therefor | TST, TXNRD3, CTH | ALDH1A1 528/4885TDP1 1101/4885CYP3A4 2295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.