Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | PRKX | P51817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL239125 | 0.89 | HDAC3 (0.37) | ALDH1A1ESR1CYP3A4ESR2TSHR | |
| SCHEMBL240545 | 0.79 | CYP2C19 (0.41) | ALDH1A1TSHRHIF1AADRA1ACYP2C19 | |
| SCHEMBL11279155 | 0.76 | BCHE (0.46) | ALDH1A1ESR1CYP3A4ESR2TSHR | |
| SCHEMBL238009 | 0.74 | — | — | |
| SCHEMBL8480813 | 0.73 | CYP2C19 (0.44) | ALDH1A1ESR1CYP3A4ESR2TSHR | |
| SCHEMBL241628 | 0.71 | — | — | |
| SCHEMBL243384 | 0.71 | GRM4 (0.36) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8483276 | 0.71 | HIF1A (0.46) | ALDH1A1ESR1CYP3A4ESR2TSHR | |
| SCHEMBL240140 | 0.70 | — | — | |
| SCHEMBL239996 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173630-B2 | Multipodal tethers for high-density attachment of redox-active moieties to substrates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-08 | — | — | US | claimed |
| CN-117881432-A | Porphyrin-hydrogen porphyrin compounds, compositions comprising the same, and methods of use thereof | 北卡罗莱纳州立大学 | 2024-04-12 | — | — | CN | disclosed |
| EP-4319823-A1 | PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF | North Carolina State University (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022216927-A9 | PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-09-14 | — | — | WO | disclosed |
| US-10919904-B2 | Northern-southern route to synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2021-02-16 | — | — | US | disclosed |
| US-10836774-B2 | Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2020-11-17 | — | — | US | disclosed |
| US-20190308985-A1 | METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS | UNITED STATES DEPARTMENT OF ENERGY | 2019-10-10 | — | — | US | disclosed |
| US-20190256521-A1 | NORTHERN-SOUTHERN ROUTE TO SYNTHESIS OF BACTERIOCHLORINS | UNITED STATES DEPARTMENT OF ENERGY | 2019-08-22 | — | — | US | disclosed |
| US-10253033-B2 | De novo synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2019-04-09 | — | — | US | disclosed |
| WO-2018102252-A1 | METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-06-07 | — | — | WO | disclosed |
| US-7501508-B2 | Methods and intermediates for the synthesis of porphyrins | NORTH CAROLINE STATE UNIVERSITY (US) | 2009-03-10 | — | — | US | disclosed |
| US-20070155963-A1 | Geometric synthesis of porphyrin rods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-07-05 | — | — | US | disclosed |
| WO-2007064842-A2 | SYNTHESIS OF CHLORINS AND PHORBINES WITH ENHANCED RED SPECTRAL FEATURES | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-06-07 | — | — | WO | disclosed |
| US-20070108438-A1 | Multypodal tethers for high-density attachment of redox-active moieties to substrates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-05-17 | — | — | US | disclosed |
| WO-2007047925-A2 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-04-26 | — | — | WO | disclosed |
| WO-2007018808-A2 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-02-15 | — | — | WO | disclosed |
| WO-2007018807-A2 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-02-15 | — | — | WO | disclosed |
| US-20070027311-A1 | Methods and intermediates for the synthesis of porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
| US-20070027312-A1 | Methods and intermediates for the synthesis of porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
| US-20060194960-A1 | infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155963-A1 | Geometric synthesis of porphyrin rods | PPOX, DLD, PYCR1 | ALDH1A1 883/4885ESR1 4393/4885CYP3A4 3397/4885 |
| US-10253033-B2 | De novo synthesis of bacteriochlorins | BCL6, ALDH1A2, ALAD | ALDH1A1 263/4885ESR1 2597/4885CYP3A4 3866/4885 |
| US-20060194960-A1 | infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices | PCNA, SCD, BCL6 | ALDH1A1 205/4885ESR1 460/4885CYP3A4 3742/4885 |
| US-20190256521-A1 | NORTHERN-SOUTHERN ROUTE TO SYNTHESIS OF BACTERIOCHLORINS | DLD, HCCS, PPIF | ALDH1A1 2805/4885ESR1 3427/4885CYP3A4 2449/4885 |
| US-10836774-B2 | Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds | PPOX, MRPL19, PYCR1 | ALDH1A1 1630/4885ESR1 1666/4885CYP3A4 739/4885 |
| US-10919904-B2 | Northern-southern route to synthesis of bacteriochlorins | DLD, HCCS, PPIF | ALDH1A1 2805/4885ESR1 3427/4885CYP3A4 2449/4885 |
| US-20190308985-A1 | METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS | PPOX, PPIC, ALAD | ALDH1A1 1003/4885ESR1 2955/4885CYP3A4 1068/4885 |
| US-20070027312-A1 | Methods and intermediates for the synthesis of porphyrins | PPOX, DHPS, POR | ALDH1A1 567/4885ESR1 3029/4885CYP3A4 146/4885 |
| US-20070027311-A1 | Methods and intermediates for the synthesis of porphyrins | PPOX, HMBS, CYC1 | ALDH1A1 917/4885ESR1 3963/4885CYP3A4 222/4885 |
| US-20070108438-A1 | Multypodal tethers for high-density attachment of redox-active moieties to substrates | DNMT1, TET1, SOD1 | ALDH1A1 77/4885ESR1 1458/4885CYP3A4 1562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.