Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL239872 | 0.79 | ALDH1A1 (0.42) | CYP2C19HIF1AALDH1A1ADRA1ACYP2D6 | |
| SCHEMBL29115700 | 0.79 | CYP2C19 (0.47) | CYP2C19HIF1AMIFSLC13A5ALDH1A1 | |
| SCHEMBL239125 | 0.76 | HDAC3 (0.37) | HIF1AALDH1A1ADRA1ATSHR | |
| SCHEMBL12258196 | 0.74 | CYP2C19 (0.45) | CYP2C19HIF1AMIFALDH1A1TSHR | |
| SCHEMBL240529 | 0.72 | — | — | |
| SCHEMBL6916093 | 0.70 | CYP2C19 (0.55) | CYP2C19HIF1AMIFSLC13A5ALDH1A1 | |
| SCHEMBL238009 | 0.68 | — | — | |
| SCHEMBL241549 | 0.68 | PGK1 (0.32) | — | |
| SCHEMBL28810886 | 0.68 | CYP2C19 (0.59) | CYP2C19HIF1AMIFALDH1A1CHRM1 | |
| SCHEMBL1604732 | 0.68 | CYP2C19 (0.59) | CYP2C19HIF1AMIFALDH1A1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173630-B2 | Multipodal tethers for high-density attachment of redox-active moieties to substrates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-08 | — | — | US | claimed |
| CN-117881432-A | Porphyrin-hydrogen porphyrin compounds, compositions comprising the same, and methods of use thereof | 北卡罗莱纳州立大学 | 2024-04-12 | — | — | CN | disclosed |
| EP-4319823-A1 | PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF | North Carolina State University (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022216927-A9 | PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-09-14 | — | — | WO | disclosed |
| US-10919904-B2 | Northern-southern route to synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2021-02-16 | — | — | US | disclosed |
| US-10836774-B2 | Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2020-11-17 | — | — | US | disclosed |
| US-20190308985-A1 | METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS | UNITED STATES DEPARTMENT OF ENERGY | 2019-10-10 | — | — | US | disclosed |
| US-20190256521-A1 | NORTHERN-SOUTHERN ROUTE TO SYNTHESIS OF BACTERIOCHLORINS | UNITED STATES DEPARTMENT OF ENERGY | 2019-08-22 | — | — | US | disclosed |
| US-10253033-B2 | De novo synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2019-04-09 | — | — | US | disclosed |
| US-20180072746-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | UNIV NORTH CAROLINA STATE (US) | 2018-03-15 | — | — | US | disclosed |
| US-7534807-B2 | infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-05-19 | — | — | US | disclosed |
| US-7501508-B2 | Methods and intermediates for the synthesis of porphyrins | NORTH CAROLINE STATE UNIVERSITY (US) | 2009-03-10 | — | — | US | disclosed |
| WO-2007078498-A1 | GEOMETRIC SYNTHESIS OF PORPHYRIN RODS | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-07-12 | — | — | WO | disclosed |
| US-20070155963-A1 | Geometric synthesis of porphyrin rods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-07-05 | — | — | US | disclosed |
| US-20070108438-A1 | Multypodal tethers for high-density attachment of redox-active moieties to substrates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-05-17 | — | — | US | disclosed |
| WO-2007047925-A2 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-04-26 | — | — | WO | disclosed |
| WO-2007018808-A2 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-02-15 | — | — | WO | disclosed |
| US-20070027311-A1 | Methods and intermediates for the synthesis of porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
| US-20070027312-A1 | Methods and intermediates for the synthesis of porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
| US-20060194960-A1 | infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155963-A1 | Geometric synthesis of porphyrin rods | PPOX, DLD, PYCR1 | CYP2C19 2501/4885HIF1A 2564/4885MIF 2526/4885 |
| US-10253033-B2 | De novo synthesis of bacteriochlorins | BCL6, ALDH1A2, ALAD | CYP2C19 2504/4885HIF1A 2135/4885MIF 2563/4885 |
| US-20060194960-A1 | infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices | PCNA, SCD, BCL6 | CYP2C19 2411/4885HIF1A 722/4885MIF 801/4885 |
| US-20190256521-A1 | NORTHERN-SOUTHERN ROUTE TO SYNTHESIS OF BACTERIOCHLORINS | DLD, HCCS, PPIF | CYP2C19 1616/4885HIF1A 2504/4885MIF 4029/4885 |
| US-10836774-B2 | Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds | PPOX, MRPL19, PYCR1 | CYP2C19 153/4885HIF1A 3933/4885MIF 3666/4885 |
| US-10919904-B2 | Northern-southern route to synthesis of bacteriochlorins | DLD, HCCS, PPIF | CYP2C19 1616/4885HIF1A 2504/4885MIF 4029/4885 |
| US-20190308985-A1 | METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS | PPOX, PPIC, ALAD | CYP2C19 411/4885HIF1A 2682/4885MIF 3642/4885 |
| US-20070027312-A1 | Methods and intermediates for the synthesis of porphyrins | PPOX, DHPS, POR | CYP2C19 174/4885HIF1A 1221/4885MIF 2956/4885 |
| US-20180072746-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | BCL6, ALDH1A2, ALAD | CYP2C19 2504/4885HIF1A 2135/4885MIF 2563/4885 |
| US-20070027311-A1 | Methods and intermediates for the synthesis of porphyrins | PPOX, HMBS, CYC1 | CYP2C19 141/4885HIF1A 1261/4885MIF 3914/4885 |
| US-20070108438-A1 | Multypodal tethers for high-density attachment of redox-active moieties to substrates | DNMT1, TET1, SOD1 | CYP2C19 3511/4885HIF1A 2137/4885MIF 1101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.