Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.48 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242285 | 0.80 | TYMS (0.53) | TYMSLMNACYP3A4NFKB1BLM | |
| SCHEMBL20235 | 0.79 | TYMS (0.85) | TYMSLMNACYP3A4NFKB1BLM | |
| SCHEMBL182326 | 0.79 | TYMS (1.00) | TYMSLMNACYP3A4NFKB1BLM | |
| SCHEMBL9662422 | 0.78 | LPAR3 (0.78) | LPAR3LPAR2 | |
| SCHEMBL22701925 | 0.77 | TYMS (0.58) | TYMSLMNACYP3A4NFKB1BLM | |
| SCHEMBL307497 | 0.77 | TYMS (0.58) | TYMSLMNACYP3A4NFKB1BLM | |
| Ammonia Solution, Strong SCHEMBL1777238 | 0.76 | TYMS (0.92) | TYMSLMNACYP3A4NFKB1BLM | |
| SCHEMBL767546 | 0.76 | TYMS (0.79) | TYMSLMNACYP3A4NFKB1BLM | |
| SCHEMBL9701682 | 0.76 | TYMS (0.79) | TYMSLMNACYP3A4NFKB1BLM | |
| Ammonia Solution, Strong SCHEMBL1643223 | 0.76 | TYMS (0.92) | TYMSLMNACYP3A4NFKB1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173630-B2 | Multipodal tethers for high-density attachment of redox-active moieties to substrates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-08 | — | — | US | claimed |
| EP-4319823-A1 | PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF | North Carolina State University (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022216927-A9 | PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-09-14 | — | — | WO | disclosed |
| US-10919904-B2 | Northern-southern route to synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2021-02-16 | — | — | US | disclosed |
| US-10836774-B2 | Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2020-11-17 | — | — | US | disclosed |
| US-20190308985-A1 | METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS | UNITED STATES DEPARTMENT OF ENERGY | 2019-10-10 | — | — | US | disclosed |
| US-20190256521-A1 | NORTHERN-SOUTHERN ROUTE TO SYNTHESIS OF BACTERIOCHLORINS | UNITED STATES DEPARTMENT OF ENERGY | 2019-08-22 | — | — | US | disclosed |
| US-10253033-B2 | De novo synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2019-04-09 | — | — | US | disclosed |
| WO-2018102252-A1 | METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-06-07 | — | — | WO | disclosed |
| US-20180072746-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | UNIV NORTH CAROLINA STATE (US) | 2018-03-15 | — | — | US | disclosed |
| US-20090191130-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-07-30 | — | — | US | disclosed |
| US-7534807-B2 | infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-05-19 | — | — | US | disclosed |
| US-7501508-B2 | Methods and intermediates for the synthesis of porphyrins | NORTH CAROLINE STATE UNIVERSITY (US) | 2009-03-10 | — | — | US | disclosed |
| US-20070155963-A1 | Geometric synthesis of porphyrin rods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-07-05 | — | — | US | disclosed |
| US-20070108438-A1 | Multypodal tethers for high-density attachment of redox-active moieties to substrates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-05-17 | — | — | US | disclosed |
| WO-2007047925-A2 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-04-26 | — | — | WO | disclosed |
| WO-2007018807-A2 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-02-15 | — | — | WO | disclosed |
| US-20070027311-A1 | Methods and intermediates for the synthesis of porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
| US-20070027312-A1 | Methods and intermediates for the synthesis of porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
| US-20060194960-A1 | infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155963-A1 | Geometric synthesis of porphyrin rods | PPOX, DLD, PYCR1 | TYMS 1124/4885LMNA 1483/4885CYP3A4 3397/4885 |
| US-10253033-B2 | De novo synthesis of bacteriochlorins | BCL6, ALDH1A2, ALAD | TYMS 1094/4885LMNA 2153/4885CYP3A4 3866/4885 |
| US-20060194960-A1 | infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices | PCNA, SCD, BCL6 | TYMS 762/4885LMNA 2225/4885CYP3A4 3742/4885 |
| US-20190256521-A1 | NORTHERN-SOUTHERN ROUTE TO SYNTHESIS OF BACTERIOCHLORINS | DLD, HCCS, PPIF | TYMS 496/4885LMNA 2242/4885CYP3A4 2449/4885 |
| US-10836774-B2 | Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds | PPOX, MRPL19, PYCR1 | TYMS 1748/4885LMNA 3706/4885CYP3A4 739/4885 |
| US-10919904-B2 | Northern-southern route to synthesis of bacteriochlorins | DLD, HCCS, PPIF | TYMS 496/4885LMNA 2242/4885CYP3A4 2449/4885 |
| US-20190308985-A1 | METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS | PPOX, PPIC, ALAD | TYMS 783/4885LMNA 2813/4885CYP3A4 1068/4885 |
| US-20070027312-A1 | Methods and intermediates for the synthesis of porphyrins | PPOX, DHPS, POR | TYMS 319/4885LMNA 1601/4885CYP3A4 146/4885 |
| US-20180072746-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | BCL6, ALDH1A2, ALAD | TYMS 1094/4885LMNA 2153/4885CYP3A4 3866/4885 |
| US-20070027311-A1 | Methods and intermediates for the synthesis of porphyrins | PPOX, HMBS, CYC1 | TYMS 503/4885LMNA 1169/4885CYP3A4 222/4885 |
| US-20070108438-A1 | Multypodal tethers for high-density attachment of redox-active moieties to substrates | DNMT1, TET1, SOD1 | TYMS 3482/4885LMNA 4719/4885CYP3A4 1562/4885 |
| US-20090191130-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | BCL6, ALDH1A2, ALAD | TYMS 1094/4885LMNA 2153/4885CYP3A4 3866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.