SCHEMBL246594

SCHEMBL246594

C=CC(=O)Oc1ccccc1-c1ccccc1I

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.44
THRA P10827 1/20 0.44
TYMS P04818 1/20 0.43
KDM4E B2RXH2 3/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
FABP7 O15540 3/20 0.34
FABP3 P05413 3/20 0.34
FABP5 Q01469 3/20 0.34
LIG1 P18858 1/20 0.33
AKT1 P31749 1/20 0.32
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
EGFR P00533 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
PKM P14618 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30007447 0.89 THRB (0.51) THRBTHRATYMSKDM4EMAPT
SCHEMBL10871851 0.89 THRB (0.51) THRBTHRATYMSKDM4EMAPT
SCHEMBL6251831 0.86 THRB (0.49) THRBTHRATYMSKDM4EMAPT
SCHEMBL23161027 0.81 FABP7 (0.48) THRBTHRATYMSKDM4EMAPT
SCHEMBL14075050 0.81 THRB (0.46) THRBTHRATYMSKDM4EMAPT
SCHEMBL29413361 0.80 THRB (0.56) THRBTHRATYMSKDM4EMAPT
SCHEMBL3841280 0.80 THRB (0.56) THRBTHRATYMSKDM4EMAPT
SCHEMBL35121 0.79 FABP3 (0.49) THRBTHRATYMSKDM4EMAPT
SCHEMBL29733244 0.79 FABP3 (0.49) THRBTHRATYMSKDM4EMAPT
SCHEMBL23207832 0.79 THRB (0.47) THRBTHRATYMSKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9221928-B2 Fluorine-containing sulfonate resin, fluorine-containing N-sulfonyloxyimide resin, resist composition and pattern formation method CENTRAL GLASS COMPANY, LIMITED (JP) 2015-12-29 US claimed
US-9989847-B2 Onium salt compound, resist composition, and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-06-05 US disclosed
US-20160259242-A1 NOVEL ONIUM SALT COMPOUND, RESIST COMPOSITION, AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-09-08 US disclosed
US-9221928-B2 Fluorine-containing sulfonate resin, fluorine-containing N-sulfonyloxyimide resin, resist composition and pattern formation method CENTRAL GLASS COMPANY, LIMITED (JP) 2015-12-29 US disclosed
US-9182664-B2 Polymerizable fluorine-containing sulfonate, fluorine-containing sulfonate resin, resist composition and pattern-forming method using same CENTRAL GLASS COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-9152045-B2 Fluorine-containing sulfonate, fluorine-containing sulfonate resin, resist composition and pattern formation method CENTRAL GLASS COMPANY, LIMITED (JP) 2015-10-06 US disclosed
US-9024058-B2 Ammonium fluoroalkanesulfonates and a synthesis method therefor CENTRAL GLASS COMPANY, LIMITED (JP) 2015-05-05 US disclosed
US-8993212-B2 Fluorine-containing sulfonic acid salts, photo-acid generator and resist composition and pattern formation method utilizing same CENTRAL GLASS COMPANY, LIMITED (JP) 2015-03-31 US disclosed
US-8846966-B2 Method for producing alkoxycarbonylfluoroalkanesulfonic acid salt CENTRAL GLASS COMPANY, LIMITED (JP) 2014-09-30 US disclosed
US-20140287359-A1 Fluorine-Containing Sulfonate, Fluorine-Containing Sulfonate Resin, Resist Composition and Pattern Formation Method CENTRAL GLASS CO LTD (JP) 2014-09-25 US disclosed
US-8283106-B2 Sulfonic acid salt and derivative thereof, photoacid generator agent, and resist material and pattern formation method using the photoacid generator agent CENTRAL GLASS COMPANY, LIMITED (JP) 2012-10-09 US disclosed
US-8222448-B2 Processes for production of 2-bromo-2,2-difluoroethanol and 2-(alkylcarbonyloxy)-1, 1-difluoroethanesulfonic acid salt CENTRAL GLASS COMPANY, LIMITED (JP) 2012-07-17 US disclosed
US-8110711-B2 Processes for production of 2-bromo-2,2-difluoroethanol and 2-(alkylcarbonyloxy)-1,1-difluoroethanesulfonic acid salt CENTRAL GLASS COMPANY, LIMITED (JP) 2012-02-07 US disclosed
US-20120004447-A1 Ammonium Fluoroalkanesulfonates and a Synthesis Method Therefor CENTRAL GLASS COMPANY, LIMITED (JP) 2012-01-05 US disclosed
US-20110319652-A1 Processes for Production of 2-Bromo-2,2-Difluoroethanol and 2-(Alkylcarbonyloxy)-1, 1-Difluoroethanesulfonic Acid Salt CENTRAL GLASS COMPANY, LIMITED (JP) 2011-12-29 US disclosed
US-20110207954-A1 Method for Producing Alkoxycarbonylfluoroalkanesulfonic Acid Salt CENTRAL GLASS COMPANY, LIMITED (JP) 2011-08-25 US disclosed
US-20110177453-A1 Fluorine-Containing Sulfonates Having Polymerizable Anions and Manufacturing Method Therefor, Fluorine-Containing Resins, Resist Compositions, and Pattern-Forming Method Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2011-07-21 US disclosed
US-20110034721-A1 2-(Alkylcarbonyloxy)-1, 1-Difluoroethanesulfonic Acid Salt and Method for Producing the Same CENTRAL GLASS COMPANY, LIMITED (JP) 2011-02-10 US disclosed
US-20110015431-A1 Processes for Production of 2-Bromo-2,2-Difluoroethanol and 2-(Alkylcarbonyloxy)-1,1-Difluoroethanesulfonic Acid Salt CENTRAL GLASS COMPANY, LIMITED (JP) 2011-01-20 US disclosed
US-20100304303-A1 Novel Sulfonic Acid Salt and Derivative Thereof, Photoacid Generator Agent, and Resist Material and Pattern Formation Method Using the Photoacid Generator Agent CENTRAL GLASS COMPANY, LIMITED (JP) 2010-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110207954-A1 Method for Producing Alkoxycarbonylfluoroalkanesulfonic Acid Salt ARSA, SLC6A5, PFAS THRB 4537/4885THRA 4052/4885TYMS 3626/4885
US-20110319652-A1 Processes for Production of 2-Bromo-2,2-Difluoroethanol and 2-(Alkylcarbonyloxy)-1, 1-Difluoroethanesulfonic Acid Salt HAO2, SULT2A1, CYP2F1 THRB 2720/4885THRA 2832/4885TYMS 2880/4885
US-20160259242-A1 NOVEL ONIUM SALT COMPOUND, RESIST COMPOSITION, AND PATTERN FORMING PROCESS LIFR, NHERF1, INSR THRB 3907/4885THRA 4110/4885TYMS 4316/4885
US-20110177453-A1 Fluorine-Containing Sulfonates Having Polymerizable Anions and Manufacturing Method Therefor, Fluorine-Containing Resins, Resist Compositions, and Pattern-Forming Method Using Same WASF2, EEF2, IKZF2 THRB 3531/4885THRA 3504/4885TYMS 3735/4885
US-20110034721-A1 2-(Alkylcarbonyloxy)-1, 1-Difluoroethanesulfonic Acid Salt and Method for Producing the Same PFAS, DDAH1, STS THRB 4431/4885THRA 4172/4885TYMS 4006/4885
US-20110015431-A1 Processes for Production of 2-Bromo-2,2-Difluoroethanol and 2-(Alkylcarbonyloxy)-1,1-Difluoroethanesulfonic Acid Salt HAO2, SULT2A1, CYP2F1 THRB 2720/4885THRA 2832/4885TYMS 2880/4885
US-20100304303-A1 Novel Sulfonic Acid Salt and Derivative Thereof, Photoacid Generator Agent, and Resist Material and Pattern Formation Method Using the Photoacid Generator Agent ARF1, ARF5, ARF6 THRB 4365/4885THRA 2756/4885TYMS 3435/4885
US-20120004447-A1 Ammonium Fluoroalkanesulfonates and a Synthesis Method Therefor NOTUM, FAR1, PFAS THRB 4247/4885THRA 4461/4885TYMS 790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.