Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL2466419

CN(C)CC#N.O=S(=O)(O)C(F)(F)F

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.34
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
GLA P06280 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9695211-B2 Method for the synthesis of phosphorus atom modified nucleic acids WAVE LIFE SCIENCES JAPAN, INC. (JP) 2017-07-04 US claimed
US-20160347780-A1 METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS WAVE LIFE SCIENCES LTD. (SG) 2016-12-01 US claimed
US-9394333-B2 Method for the synthesis of phosphorus atom modified nucleic acids WAVE LIFE SCIENCES JAPAN (JP) 2016-07-19 US claimed
US-20110294124-A1 METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS WAVE LIFE SCIENCES LTD. (SG) 2011-12-01 US claimed
EP-2370451-A2 METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS Chiralgen, Ltd. (JP) 2011-10-05 EP claimed
WO-2010064146-A2 METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS CHIRALGEN, LTD. (JP) 2010-06-10 WO claimed
US-12637672-B2 Oligonucleotide compositions and methods thereof WAVE LIFE SCIENCES LTD. (SG) 2026-05-26 US disclosed
CN-122031506-A Chiral control 波涛生命科学有限公司 2026-05-15 CN disclosed
US-12583883-B2 Asymmetric auxiliary group WAVE LIFE SCIENCES LTD. (SG) 2026-03-24 US disclosed
US-20260062435-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF WAVE LIFE SCIENCES LTD (SG) 2026-03-05 US disclosed
US-20260055133-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS WAVE LIFE SCIENCES LTD (SG) 2026-02-26 US disclosed
US-12552743-B2 Oligonucleotide compositions and methods of use thereof WAVE LIFE SCIENCES LTD. (SG) 2026-02-17 US disclosed
US-12486505-B2 Oligonucleotide compositions and methods thereof WAVE LIFE SCIENCES LTD. (SG) 2025-12-02 US disclosed
EP-2872147-A2 CHIRAL CONTROL Wave Life Sciences Pte. Ltd. (SG) 2015-05-20 EP disclosed
EP-2872485-A1 ASYMMETRIC AUXILIARY GROUP WaVe Life Sciences Japan (JP) 2015-05-20 EP disclosed
WO-2014010250-A1 ASYMMETRIC AUXILIARY GROUP CHIRALGEN, LTD. (JP) 2014-01-16 WO disclosed
WO-2014012081-A2 CHIRAL CONTROL ONTORII, INC. (US) 2014-01-16 WO disclosed
US-20110294124-A1 METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS WAVE LIFE SCIENCES LTD. (SG) 2011-12-01 US disclosed
EP-2370451-A2 METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS Chiralgen, Ltd. (JP) 2011-10-05 EP disclosed
WO-2010064146-A2 METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS CHIRALGEN, LTD. (JP) 2010-06-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062435-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF NSUN3, METTL3, RNASE1 DPP4 1542/4885CHRM2 2860/4885CHRM4 2144/4885
US-12552743-B2 Oligonucleotide compositions and methods of use thereof NSUN3, NSUN2, SNRPA1 DPP4 3824/4885CHRM2 4146/4885CHRM4 4000/4885
US-12583883-B2 Asymmetric auxiliary group AGL, RNMT, NSUN2 DPP4 3474/4885CHRM2 1746/4885CHRM4 1627/4885
US-12486505-B2 Oligonucleotide compositions and methods thereof RBM17, HNRNPA2B1, HNRNPA1 DPP4 2846/4885CHRM2 4784/4885CHRM4 4692/4885
US-20110294124-A1 METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS PNP, ADAR, NUDT1 DPP4 1175/4885CHRM2 4704/4885CHRM4 4014/4885
US-20260055133-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS NSUN2, NSUN3, NOP2 DPP4 4435/4885CHRM2 1790/4885CHRM4 1771/4885
US-12637672-B2 Oligonucleotide compositions and methods thereof UPF1, SMN1; SMN2, RNGTT DPP4 1671/4885CHRM2 4172/4885CHRM4 3889/4885
US-20160347780-A1 METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS ADAR, PNP, NUDT1 DPP4 843/4885CHRM2 4703/4885CHRM4 3884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.