Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25040 | 0.96 | TSHR (0.43) | TSHRALDH1A1THRB | |
| SCHEMBL28381594 | 0.94 | TSHR (0.42) | TSHRALDH1A1THRB | |
| Methane SCHEMBL7698380 | 0.94 | TSHR (0.42) | TSHRALDH1A1THRB | |
| Methacrylic Acid SCHEMBL10956923 | 0.90 | TSHR (0.39) | TSHRALDH1A1THRB | |
| Trimethylammonium SCHEMBL7056227 | 0.90 | TSHR (0.39) | TSHRALDH1A1THRB | |
| Methacrylic Acid SCHEMBL10953670 | 0.90 | TSHR (0.39) | TSHRALDH1A1THRB | |
| Methacrylic Acid SCHEMBL5369165 | 0.90 | TSHR (0.39) | TSHRALDH1A1THRB | |
| SCHEMBL4920106 | 0.88 | TSHR (0.42) | TSHRALDH1A1THRB | |
| Phosphoric Acid SCHEMBL16296461 | 0.88 | TSHR (0.38) | TSHRALDH1A1THRB | |
| SCHEMBL5366041 | 0.88 | ALDH1A1 (0.58) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250381127-A1 | COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER | OREAL (FR) | 2025-12-18 | — | — | US | disclosed |
| WO-2025132142-A1 | INVERT EMULSION COMPRISING PULLULAN, AN APOLAR HYDROCARBON-BASED OIL, A SILICONE FILM-FORMING POLYMER AND A DYESTUFF, AND MAKEUP PROCESS | L'OREAL (FR) | 2025-06-26 | — | — | WO | disclosed |
| WO-2025082655-A1 | LOW WATER CONTENT W/O EMULSION COMPRISING A HYDROPHOBIC FILM-FORMING POLYMER, A LINEAR SILICONE POLYOL, HYALURONIC ACID, A VITAMIN B3 AND A XANTHINE BASE | L'OREAL (FR) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025061338-A1 | SOLID COMPOSITION IN POWDER FORM COMPRISING A FILM-FORMING POLYMER IN THE SOLID STATE | L'OREAL (FR) | 2025-03-27 | — | — | WO | disclosed |
| WO-2025061352-A1 | PROCESS FOR PREPARING A COSMETIC COMPOSITION COMPRISING A PULVERULENT PHASE AND A FILM-FORMING POLYMER SOLUBILIZED IN A VOLATILE SOLVENT; AND PIGMENT FORMULATION. | L'OREAL (FR) | 2025-03-27 | — | — | WO | disclosed |
| US-20250041171-A1 | EMULSION COMPOSITIONS CONTAINING CARBOSILOXANE DENDRIMER COMPOUND AND AQUEOUS PHASE FILM FORMER | L'OREAL (FR) | 2025-02-06 | — | — | US | disclosed |
| US-12186417-B2 | Skin perfecting cosmetic compositions and methods of use | L'OREAL (FR) | 2025-01-07 | — | — | US | disclosed |
| EP-4452193-A1 | COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER | L'OREAL (FR) | 2024-10-30 | — | — | EP | disclosed |
| CN-118382418-A | Cosmetic composition comprising polyhydroxyalkanoate copolymer with (unsaturated) hydrocarbon-based chain and silicone polymer | 欧莱雅 | 2024-07-23 | — | — | CN | disclosed |
| US-12011494-B2 | Skin perfecting cosmetic compositions and methods of use | L'OREAL (FR) | 2024-06-18 | — | — | US | disclosed |
| US-20120263662-A1 | Copolymer Having Carbosiloxane Dendrimer Structure, And Composition And Cosmetic Containing The Same | DOW TORAY CO., LTD. (JP) | 2012-10-18 | — | — | US | disclosed |
| US-20120251605-A1 | Surface-Treatment Agent For Powder For Use In Cosmetic And Cosmetic Containing Powder Treated With The Same | DOW TORAY CO., LTD. (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120100089-A1 | COSMETIC COMPOSITION FOR MAKEUP AND/OR KERATIN MATERIAL CARE, BASED ON A MIXTURE OF RESINS MQ AND T-PR, AND MAKEUP METHOD | L'OREAL (FR) | 2012-04-26 | — | — | US | disclosed |
| US-20120064019-A1 | COSMETIC COMPOSITION FOR MAKING-UP AND/OR CARING FOR KERATIN MATERIALS AND MAKE-UP METHOD | L'OREAL (FR) | 2012-03-15 | — | — | US | disclosed |
| US-20120003167-A1 | COSMETIC COMPOSITION COMPRISING SILOXANE RESINS AND AT LEAST ONE PHENYL SILICONE OIL | L'OREAL (FR) | 2012-01-05 | — | — | US | disclosed |
| WO-2011078407-A1 | COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION AND COSMETIC CONTAINING THE SAME | DOW CORNING TORAY CO., LTD. (JP) | 2011-06-30 | — | — | WO | disclosed |
| US-20080003195-A1 | Cosmetic composition comprising at least one vinyl polymer and at least one olefin copolymer | L'OREAL S.A. (FR) | 2008-01-03 | — | — | US | disclosed |
| EP-0963751-B1 | Cosmetic raw material, cosmetic product, and method for manufacturing cosmetic raw material | DOW CORNING TORAY SILICONE (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-6280748-B1 | TREATING SKIN OR HAIR BY APPLYING TO SKIN OR HAIR COSMETIC PRODUCT COMPRISING SOLUTION OR DISPERSION OF POLYMER IN LIQUID SELECTED FROM SILICONE OILS, ORGANIC OILS, ALCOHOLS AND WATER, POLYMER HAVING CARBOSILOXANE DENDRIMER IN ITS SIDE CHAIN | DOW CORNING TORAY SILICONE, LTD. (JP) | 2001-08-28 | — | — | US | disclosed |
| EP-0963751-A2 | Cosmetic raw material, cosmetic product, and method for manufacturing cosmetic raw material | Dow Corning Toray Silicone Company, Ltd. (JP) | 1999-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12186417-B2 | Skin perfecting cosmetic compositions and methods of use | CUTA, DSG1, SMURF1 | TSHR 1097/4885ALDH1A1 3659/4885THRB 2742/4885 |
| US-20120003167-A1 | COSMETIC COMPOSITION COMPRISING SILOXANE RESINS AND AT LEAST ONE PHENYL SILICONE OIL | QSOX1, RXRB, PRXL2A | TSHR 1259/4885ALDH1A1 2479/4885THRB 400/4885 |
| US-20120263662-A1 | Copolymer Having Carbosiloxane Dendrimer Structure, And Composition And Cosmetic Containing The Same | TAS2R8, CUTA, TAS2R43 | TSHR 1436/4885ALDH1A1 2522/4885THRB 1909/4885 |
| US-20120064019-A1 | COSMETIC COMPOSITION FOR MAKING-UP AND/OR CARING FOR KERATIN MATERIALS AND MAKE-UP METHOD | PLOD3, ALOX15, ELOVL1 | TSHR 2894/4885ALDH1A1 3221/4885THRB 747/4885 |
| US-20080003195-A1 | Cosmetic composition comprising at least one vinyl polymer and at least one olefin copolymer | KRT18, DSG1, MARK1 | TSHR 4464/4885ALDH1A1 753/4885THRB 3072/4885 |
| US-20120251605-A1 | Surface-Treatment Agent For Powder For Use In Cosmetic And Cosmetic Containing Powder Treated With The Same | CUTA, GPKOW, TAS2R8 | TSHR 606/4885ALDH1A1 2691/4885THRB 1203/4885 |
| US-20250381127-A1 | COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER | H1-0, PARN, FASN | TSHR 1030/4885ALDH1A1 2361/4885THRB 548/4885 |
| US-20120100089-A1 | COSMETIC COMPOSITION FOR MAKEUP AND/OR KERATIN MATERIAL CARE, BASED ON A MIXTURE OF RESINS MQ AND T-PR, AND MAKEUP METHOD | KRT18, TERB1, VIM | TSHR 816/4885ALDH1A1 3581/4885THRB 194/4885 |
| US-20250041171-A1 | EMULSION COMPOSITIONS CONTAINING CARBOSILOXANE DENDRIMER COMPOUND AND AQUEOUS PHASE FILM FORMER | CCNO, CUTA, SQLE | TSHR 3701/4885ALDH1A1 1418/4885THRB 4023/4885 |
| US-12011494-B2 | Skin perfecting cosmetic compositions and methods of use | CUTA, DSG1, SMURF1 | TSHR 1097/4885ALDH1A1 3659/4885THRB 2742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.