SCHEMBL2479894

SCHEMBL2479894

Cc1ccc(N(c2ccc(C)cc2)c2ccc(-c3c4ccccc4c(N(c4ccc(C)cc4)c4ccc(C)cc4)c4ccccc34)c3ccccc23)cc1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31
CYP2C19 P33261 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29444796 1.00 KEAP1 (0.31) KEAP1NFE2L2CYP2C19ALDH1A1TSHR
SCHEMBL13658642 0.94 ALDH1A1 (0.34) KEAP1NFE2L2CYP2C19ALDH1A1TSHR
SCHEMBL14537292 0.92 RELA (0.34) NFE2L2ALDH1A1
SCHEMBL14537297 0.91 NFE2L2 (0.33) NFE2L2ALDH1A1
SCHEMBL2449457 0.87 RXRA (0.32) CYP2C19ALDH1A1
SCHEMBL29444858 0.87 RXRA (0.32) CYP2C19ALDH1A1
SCHEMBL14537296 0.85 RELA (0.38) NFE2L2ALDH1A1
SCHEMBL9971781 0.85 RELA (0.38) NFE2L2ALDH1A1
SCHEMBL14537300 0.84 APP (0.33) NFE2L2ALDH1A1
SCHEMBL13948910 0.83 CYP2C19 (0.38) KEAP1NFE2L2CYP2C19ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473315-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-11-18 US disclosed
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-03-06 US disclosed
US-12185625-B2 Organic electroluminescence element, display device, and lighting device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-12-31 US disclosed
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-10-31 US disclosed
CN-111527094-B Compound, polymer compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2024-03-26 CN disclosed
CN-116987108-A Polycyclic aromatic compound, material for organic element, composition for forming light-emitting layer, organic electroluminescent element, and device 学校法人关西学院 2023-11-03 CN disclosed
CN-116997557-A Polycyclic aromatic compound and organic electroluminescent element 学校法人关西学院 2023-11-03 CN disclosed
CN-116888132-A Polycyclic aromatic compounds 学校法人关西学院 2023-10-13 CN disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
CN-110719914-B Polycyclic aromatic compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2023-07-28 CN disclosed
EP-2784057-A1 BENZOFLUORENE COMPOUND, MATERIAL FOR LUMINESCENT LAYER USING SAID COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE JNC Corporation (JP) 2014-10-01 EP disclosed
EP-2669262-A1 NOVEL ANTHRACENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC Corporation (JP) 2013-12-04 EP disclosed
US-20130292665-A1 NOVEL ANTHRACENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC CORPORATION (JP) 2013-11-07 US disclosed
US-20130134405-A1 BENZOFLUORENE COMPOUND, EMISSION MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE JNC CORPORATION (JP) 2013-05-30 US disclosed
EP-1640430-B1 Luminescent material and organic electroluminescent device using the same JNC CORP (JP) 2011-09-21 EP disclosed
EP-2177586-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2010-04-21 EP disclosed
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device JNC CORPORATION (JP) 2008-07-03 US disclosed
EP-1640430-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2006-03-29 EP disclosed
US-20060014046-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2006-01-19 US disclosed
US-6582837-B1 Device having one or more organic thin layers including luminescent layer between anode and cathode, wherein at least one layer contains selected compound or compounds; exhibits higher-luminance luminescence than conventional device NEC CORPORATION (JP) 2003-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, EML4, ELOC KEAP1 1365/4885NFE2L2 353/4885CYP2C19 2134/4885
US-20230276708-A1 Polycyclic aromatic compound ACVR1B, XDH, AHR KEAP1 1370/4885NFE2L2 814/4885CYP2C19 32/4885
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device LEF1, TRPA1, BRD8 KEAP1 962/4885NFE2L2 47/4885CYP2C19 359/4885
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 KEAP1 1769/4885NFE2L2 63/4885CYP2C19 987/4885
US-12473315-B2 Polycyclic aromatic compound PAH, ALK, AOC2 KEAP1 1769/4885NFE2L2 63/4885CYP2C19 987/4885
US-20060014046-A1 Luminescent material and organic electroluminescent device using the same C1S, EPB41, EPB41L2 KEAP1 385/4885NFE2L2 358/4885CYP2C19 1071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.