SCHEMBL2520205

SCHEMBL2520205

CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)Oc1cc(C=Cc2ccc(O)cc2)cc(OC(=O)CCCCCCC/C=C\C/C=C\C/C=C\CC)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
CYP3A4 P08684 3/20 0.53
ALOX15 P16050 2/20 0.53
HSD17B10 Q99714 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
TSHR P16473 1/20 0.53
PTGS2 P35354 3/20 0.46
NR1I2 O75469 2/20 0.46
PGR P06401 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
PDE4D Q08499 1/20 0.46
MAPT P10636 4/20 0.45
KDM4E B2RXH2 3/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
F7 P08709 2/20 0.45
F3 P13726 2/20 0.45
CYP19A1 P11511 2/20 0.45
PTGS1 P23219 2/20 0.45
LMNA P02545 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2519158 0.97 ALDH1A1 (0.52) ALDH1A1CYP3A4ALOX15HSD17B10TDP1
SCHEMBL2518028 0.93 PSMB11 (0.48) ALDH1A1CYP3A4ALOX15HSD17B10TDP1
SCHEMBL2517222 0.93 ALDH1A1 (0.55) ALDH1A1CYP3A4ALOX15HSD17B10TDP1
SCHEMBL2518096 0.92 ALDH1A1 (0.52) ALDH1A1CYP3A4ALOX15HSD17B10TDP1
SCHEMBL2514397 0.91 PSMB11 (0.50) ALDH1A1CYP3A4ALOX15PTGS2MAPT
SCHEMBL4097267 0.91 PSMB11 (0.50) ALDH1A1CYP3A4ALOX15PTGS2MAPT
SCHEMBL2513369 0.90 PSMB11 (0.47) ALDH1A1CYP3A4ALOX15HSD17B10TDP1
SCHEMBL19873147 0.90 ALDH1A1 (0.54) ALDH1A1CYP3A4ALOX15HSD17B10TDP1
SCHEMBL2518545 0.90 ALDH1A1 (0.54) ALDH1A1CYP3A4ALOX15HSD17B10TDP1
SCHEMBL4096611 0.90 MAPT (0.51) ALDH1A1CYP3A4ALOX15HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140127146-A1 Linoleic And Linolenic Acid Esters Of Resveratrol And Cosmetic Compositions MAES DANIEL H (US) 2014-05-08 US claimed
US-9861564-B2 Valeric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT, LLC (US) 2018-01-09 US disclosed
US-9782335-B2 Malic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2017-10-10 US disclosed
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-10-20 US disclosed
EP-2445511-B1 SKIN REPAIR COMPOSITIONS COMPRISING CIRCADIAN GENE ACTIVATORS AND A SYNERGISTIC COMBINATION OF SIRT1 GENE ACTIVATORS ELC MAN LLC (US) 2016-09-07 EP disclosed
US-9358194-B2 Succinic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2016-06-07 US disclosed
US-9295621-B2 Emulsion cosmetic compositions containing resveratrol derivatives and silicone surfactant ELC MANAGEMENT LLC (US) 2016-03-29 US disclosed
US-20160038389-A1 Succinic Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-02-11 US disclosed
US-9180316-B2 Butyric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2015-11-10 US disclosed
US-9162083-B2 Linoleic and Linolenic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2015-10-20 US disclosed
US-8084496-B2 Resveratrol ferulate compounds and compositions ELC MANAGEMENT LLC (US) 2011-12-27 US disclosed
US-20110250251-A1 Cosmetic Methods And Compositions For Repairing Human Skin MAES DANIEL H 2011-10-13 US disclosed
US-20100216879-A1 Resveratrol Ferulate Compounds And Compositions MAES DANIEL H 2010-08-26 US disclosed
US-20100080845-A1 Cosmetic Methods And Compositions For Repairing Human Skin MAES DANIEL H 2010-04-01 US disclosed
US-20090047309-A1 COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN ELC MANAGEMENT LLC 2009-02-19 US disclosed
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035243-A1 Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035242-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 US disclosed
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant ELC MANAGEMENT LLC 2009-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090035243-A1 Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives RB1, SIRT1, EP300 ALDH1A1 608/4885CYP3A4 3306/4885ALOX15 2910/4885
US-20090035242-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone SQLE, SMURF1, PIK3R1 ALDH1A1 3102/4885CYP3A4 3607/4885ALOX15 445/4885
US-20100216879-A1 Resveratrol Ferulate Compounds And Compositions FER, FOLR1, FOLR2 ALDH1A1 1726/4885CYP3A4 386/4885ALOX15 2713/4885
US-20090047309-A1 COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN CUTA, ERCC1, OGG1 ALDH1A1 527/4885CYP3A4 1901/4885ALOX15 867/4885
US-20110250251-A1 Cosmetic Methods And Compositions For Repairing Human Skin CUTA, ERCC1, OGG1 ALDH1A1 527/4885CYP3A4 1901/4885ALOX15 867/4885
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions CUTA, SUV39H1, RARA ALDH1A1 717/4885CYP3A4 272/4885ALOX15 498/4885
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant SMURF1, CUTA, SMURF2 ALDH1A1 3004/4885CYP3A4 3939/4885ALOX15 1416/4885
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent CUTA, LRAT, RARA ALDH1A1 2717/4885CYP3A4 3477/4885ALOX15 151/4885
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent SMARCC1, RARG, RARA ALDH1A1 2613/4885CYP3A4 3430/4885ALOX15 1327/4885
US-20100080845-A1 Cosmetic Methods And Compositions For Repairing Human Skin CUTA, ERCC1, OGG1 ALDH1A1 527/4885CYP3A4 1901/4885ALOX15 867/4885
US-20160038389-A1 Succinic Acid Esters Of Resveratrol And Cosmetic Compositions SUCNR1, SIRT1, SUCLA2 ALDH1A1 588/4885CYP3A4 1000/4885ALOX15 1491/4885
US-20140127146-A1 Linoleic And Linolenic Acid Esters Of Resveratrol And Cosmetic Compositions LRAT, ELOVL1, ELOVL6 ALDH1A1 529/4885CYP3A4 3020/4885ALOX15 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.