SCHEMBL2561950

SCHEMBL2561950

CC(N)Cc1cccc(F)c1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PNMT P11086 2/20 0.60
HTR2A P28223 2/20 0.59
HTR2C P28335 2/20 0.59
HTR2B P41595 2/20 0.59
TAAR1 Q96RJ0 5/20 0.59
SLC6A2 P23975 2/20 0.59
MAOA P21397 1/20 0.59
SLC6A4 P31645 1/20 0.59
SLC6A3 Q01959 1/20 0.59
SIGMAR1 Q99720 1/20 0.59
CYP2A6 P11509 1/20 0.59
ADORA2A P29274 1/20 0.59
ADORA1 P30542 1/20 0.59
SLC1A1 P43005 2/20 0.56
IDO1 P14902 2/20 0.52
AGXT P21549 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29410132 1.00 PNMT (0.60) PNMTHTR2AHTR2CHTR2BTAAR1
SCHEMBL14478266 1.00 PNMT (0.60) PNMTHTR2AHTR2CHTR2BTAAR1
SCHEMBL1530031 1.00 PNMT (0.60) PNMTHTR2AHTR2CHTR2BTAAR1
Hydrochloric Acid SCHEMBL6819301 0.98 PNMT (0.58) PNMTHTR2AHTR2CHTR2BTAAR1
SCHEMBL2623871 0.85 TAAR1 (0.50) HTR2AHTR2CHTR2BTAAR1SLC6A2
SCHEMBL3130819 0.85 SLC1A1 (0.50) PNMTHTR2AHTR2CHTR2BTAAR1
SCHEMBL24152546 0.84 TAAR1 (0.73) PNMTHTR2AHTR2CHTR2BTAAR1
SCHEMBL13387614 0.84 TAAR1 (0.73) PNMTHTR2AHTR2CHTR2BTAAR1
SCHEMBL2210039 0.83 SLC1A1 (0.56) TAAR1SLC1A1IDO1AGXT
SCHEMBL21417631 0.82 SLC1A1 (0.51) HTR2AHTR2CHTR2BTAAR1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023107715-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2023-06-15 WO claimed
US-9435816-B2 Deuterium free, stable isotope labeled 2-phenylethylamine hallucinogens and/or stimulants, methods of their preparation and their use CHIRON AS (NO) 2016-09-06 US claimed
US-20140227792-A1 DEUTERIUM FREE, STABLE ISOTOPE LABELED 2-PHENYLETHYLAMINE HALLUCINOGENS AND/OR STIMULANTS, METHODS OF THEIR PREPARATION AND THEIR USE CHIRON A/S (NO) 2014-08-14 US claimed
WO-2013014287-A2 DEUTERIUM FREE, STABLE ISOTOPE LABELED 2-PHENYLETHYLAMINE HALLUCINOGENS AND/OR STIMULANTS, METHODS OF THEIR PREPARATION AND THEIR USE CHIRON AS (NO) 2013-01-31 WO claimed
EP-2551675-A1 Deuterium free, stable isotope labeled 2-phenylethylamine hallucinogens and/or stimulants, methods fo their preparation and their use Chiron AS (NO) 2013-01-30 EP claimed
EP-1200395-B1 UREA DERIVATIVES AS INHIBITORS OF CCR-3 RECEPTOR KIRIN BREWERY (JP) 2006-03-29 EP claimed
US-12599578-B2 Compositions comprising enzyme-cleavable prodrugs and controlled release nafamostat and methods of use thereof Ensysce Biosciences Inc. (US) 2026-04-14 US disclosed
US-20260027148-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS BEXSON BIOMEDICAL INC (US) 2026-01-29 US disclosed
EP-4683622-A1 NON-DISTILLATIVE PROCESS FOR MANUFACTURING HIGH PURITY AMPHETAMINES Pharmapotheca A, Inc. (US) 2026-01-28 EP disclosed
US-12534428-B2 Non-distillative process for manufacturing high purity amphetamines Pharmapotheca A, Inc. (US) 2026-01-27 US disclosed
US-20260014190-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS BEXSON BIOMEDICAL INC (US) 2026-01-15 US disclosed
US-20260014191-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS BEXSON BIOMEDICAL INC (US) 2026-01-15 US disclosed
US-12472201-B2 Complexing agent salt formulations of pharmaceutical compounds BEXSON BIOMEDICAL, INC. (US) 2025-11-18 US disclosed
US-20130059914-A1 Compositions Comprising Enzyme-Cleavable Amphetamine Prodrugs and Inhibitors Thereof SIGNATURE THERAPEUTICS, INC. (US) 2013-03-07 US disclosed
EP-2560486-A1 COMPOSITIONS COMPRISING ENZYME-CLEAVABLE AMPHETAMINE PRODRUGS AND INHIBITORS THEREOF Signature Therapeutics, Inc. (US) 2013-02-27 EP disclosed
WO-2013014287-A2 DEUTERIUM FREE, STABLE ISOTOPE LABELED 2-PHENYLETHYLAMINE HALLUCINOGENS AND/OR STIMULANTS, METHODS OF THEIR PREPARATION AND THEIR USE CHIRON AS (NO) 2013-01-31 WO disclosed
EP-2551675-A1 Deuterium free, stable isotope labeled 2-phenylethylamine hallucinogens and/or stimulants, methods fo their preparation and their use Chiron AS (NO) 2013-01-30 EP disclosed
US-8343928-B2 Monomethylvaline compounds having phenylalanine side-chain replacements at the C-terminus SEATTLE GENETICS, INC. (US) 2013-01-01 US disclosed
US-20120232066-A1 COMPOSITIONS FOR REDUCING RISK OF ADVERSE EVENTS CAUSED BY DRUG-DRUG INTERACTIONS SIGNATURE THERAPEUTICS, INC. 2012-09-13 US disclosed
WO-2011133348-A1 COMPOSITIONS COMPRISING ENZYME-CLEAVABLE AMPHETAMINE PRODRUGS AND INHIBITORS THEREOF PHARMACOFORE, INC. (US) 2011-10-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140227792-A1 DEUTERIUM FREE, STABLE ISOTOPE LABELED 2-PHENYLETHYLAMINE HALLUCINOGENS AND/OR STIMULANTS, METHODS OF THEIR PREPARATION AND THEIR USE PNMT, HTR2C, HTR2A PNMT 1/4885HTR2A 3/4885HTR2C 2/4885
US-20260014191-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS SLC6A4, SLC6A3, SIGMAR1 PNMT 124/4885HTR2A 99/4885HTR2C 39/4885
US-12534428-B2 Non-distillative process for manufacturing high purity amphetamines SMS, SRMS, SRM PNMT 181/4885HTR2A 118/4885HTR2C 126/4885
US-20260027148-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS SLC6A3, SIGMAR1, SLC6A4 PNMT 127/4885HTR2A 64/4885HTR2C 33/4885
US-20120232066-A1 COMPOSITIONS FOR REDUCING RISK OF ADVERSE EVENTS CAUSED BY DRUG-DRUG INTERACTIONS CYP2C19, CYP3A5, CYP3A4 PNMT 1911/4885HTR2A 823/4885HTR2C 673/4885
US-12599578-B2 Compositions comprising enzyme-cleavable prodrugs and controlled release nafamostat and methods of use thereof OPRK1, OPRL1, OPRM1 PNMT 3131/4885HTR2A 2491/4885HTR2C 1619/4885
US-20130059914-A1 Compositions Comprising Enzyme-Cleavable Amphetamine Prodrugs and Inhibitors Thereof ACHE, COMT, CES2 PNMT 49/4885HTR2A 375/4885HTR2C 227/4885
US-12472201-B2 Complexing agent salt formulations of pharmaceutical compounds SLC10A1, SLC5A6, MC2R PNMT 3443/4885HTR2A 2775/4885HTR2C 2307/4885
US-20260014190-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS SIGMAR1, OPRK1, SLC6A2 PNMT 89/4885HTR2A 33/4885HTR2C 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.