Methacrylic Acid

Methacrylic Acid

SCHEMBL2578710

C=C(C)C(=O)O.CC=C(C)C(N)=O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.52
LDHA P00338 1/20 0.38
LDHB P07195 1/20 0.38
LMNA P02545 1/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL3428658 1.00 TDP1 (0.52) TDP1LDHALDHBLMNAALOX15
Methacrylic Acid SCHEMBL28959640 0.91 TDP1 (0.44) TDP1LDHALDHB
SCHEMBL3117839 0.90 TDP1 (0.67) TDP1LDHALMNAALOX15BLM
SCHEMBL3117838 0.90 TDP1 (0.67) TDP1LDHALMNAALOX15BLM
SCHEMBL29774226 0.84 LDHA (0.42) TDP1LDHALDHBLMNAALOX15
Carbamic Acid SCHEMBL28266632 0.84 ACHE (0.44) TDP1LDHALDHBLMNAALOX15
Ethylene SCHEMBL11567182 0.84
SCHEMBL5214305 0.84
SCHEMBL9673 0.84
SCHEMBL15325 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10920062-B2 Composition comprising a multistage polymer and two different (meth)acrylic polymers, its method of preparation and article comprising it ARKEMA FRANCE (FR) 2021-02-16 US claimed
US-8048912-B2 Benzopyran derivatives having inhibitory activities against liver fibrosis and cirrhosis and their pharmaceutical uses SK CHEMICALS CO., LTD. (KR) 2011-11-01 US claimed
US-20090118302-A1 Novel Benzopyran Derivatives Having Inhibitory Activities Against Liver Fibrosis and Cirrhosis and Their Pharmaceutical Uses KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2009-05-07 US claimed
US-7371874-B2 6-Alkylamino-2-methyl-2′-(N-methyl substituted sulfonamido)methyl-2H-1-benzopyran derivative as anti-inflammatory inhibitor KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2008-05-13 US claimed
US-7368575-B2 6-alkylamino-2,2′-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2008-05-06 US claimed
US-20070049621-A1 6-Alkylamino-2-methyl-2'-(N-methyl substituted sulfonamido)methyl-2H-1-benzopyran derivative as anti-inflammatory inhibitor KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 2007-03-01 US claimed
WO-2006070984-A1 NOVEL BENZOPYRAN DERIVATIVES HAVING INHIBITORY ACTIVITIES AGAINST LIVER FIBROSIS AND CIRRHOSIS AND THEIR PHARMACEUTICAL USES SK CHEMICALS, CO., LTD. (KR) 2006-07-06 WO claimed
US-20050203145-A1 6-alkylamino-2,2'-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 2005-09-15 US claimed
US-6908942-B2 6-amino-2,2-dimethyl-3,4,6-trisubstituted benzopyran derivatives and their construction by parallel synthesis on solid-phase KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2005-06-21 US claimed
US-20040097580-A1 Novel 6-amino-2,2-dimethyl-3,4,6-trisubstituted benzopyran derivatives and their construction by parallel synthesis on solid-phase KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 2004-05-20 US claimed
CN-106832310-B A kind of degradable selfreparing hydrogel and the preparation method and application thereof 河北大学 2019-09-24 CN disclosed
CN-110121501-A Phosphorous (methyl) acrylate derivative 片山化学工业株式会社 2019-08-13 CN disclosed
CN-110023536-A Method of depositing polymer layers for sensor applications via hot filament chemical vapor deposition 应用材料公司 2019-07-16 CN disclosed
US-8048912-B2 Benzopyran derivatives having inhibitory activities against liver fibrosis and cirrhosis and their pharmaceutical uses SK CHEMICALS CO., LTD. (KR) 2011-11-01 US disclosed
EP-2255228-A1 LENSES COMPRISING AMPHIPHILIC MULTIBLOCK COPOLYMERS Bausch & Lomb Incorporated (US) 2010-12-01 EP disclosed
US-20040097580-A1 Novel 6-amino-2,2-dimethyl-3,4,6-trisubstituted benzopyran derivatives and their construction by parallel synthesis on solid-phase KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 2004-05-20 US disclosed
WO-2002002721-A2 TOY BUBBLEMAKING SOLUTION HELIOGENESIS, INC. (US) 2002-01-10 WO disclosed
EP-0672049-A4 SUPPORT FOR THE SYNTHESIS OF MODULAR POLYMERS. CHIRON MIMOTOPES PTY LTD (AU) 1997-10-15 EP disclosed
EP-0672049-A1 SUPPORT FOR THE SYNTHESIS OF MODULAR POLYMERS CHIRON MIMOTOPES PTY. LTD. (AU) 1995-09-20 EP disclosed
WO-1994011388-A1 SUPPORT FOR THE SYNTHESIS OF MODULAR POLYMERS CHIRON MIMOTOPES PTY. LTD. (AU) 1994-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070049621-A1 6-Alkylamino-2-methyl-2'-(N-methyl substituted sulfonamido)methyl-2H-1-benzopyran derivative as anti-inflammatory inhibitor LTA4H, LTC4S, LTB4R TDP1 4006/4885LDHA 2575/4885LDHB 2206/4885
US-20040097580-A1 Novel 6-amino-2,2-dimethyl-3,4,6-trisubstituted benzopyran derivatives and their construction by parallel synthesis on solid-phase GOT2, DUOX2, LOX TDP1 1250/4885LDHA 1085/4885LDHB 1947/4885
US-20050203145-A1 6-alkylamino-2,2'-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor ALOX5, LOX, ALOX15 TDP1 3445/4885LDHA 759/4885LDHB 1178/4885
US-20090118302-A1 Novel Benzopyran Derivatives Having Inhibitory Activities Against Liver Fibrosis and Cirrhosis and Their Pharmaceutical Uses TGFBR1, TGFBR2, TGFB1 TDP1 3381/4885LDHA 2079/4885LDHB 2218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.