Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL333986 | 0.98 | KDM4E (0.39) | EGFRMEN1KMT2ALMNAHTT | |
| SCHEMBL2626789 | 0.89 | EGFR (0.46) | EGFRMEN1KMT2APOLBCASP6 | |
| Iodide SCHEMBL30367691 | 0.88 | EGFR (0.44) | EGFRMEN1KMT2APOLBCASP6 | |
| Hydrochloric Acid SCHEMBL7229751 | 0.88 | EGFR (0.44) | EGFRMEN1KMT2APOLBCASP6 | |
| SCHEMBL30165715 | 0.84 | KMT2A (0.50) | EGFRMEN1KMT2ALMNAHTT | |
| SCHEMBL146313 | 0.84 | KMT2A (0.50) | EGFRMEN1KMT2ALMNAHTT | |
| Hydrochloric Acid SCHEMBL40555 | 0.82 | MAPT (0.50) | EGFRMEN1KMT2ALMNAHTT | |
| Iodide SCHEMBL11279046 | 0.82 | KMT2A (0.48) | EGFRMEN1KMT2ALMNAHTT | |
| SCHEMBL13097886 | 0.81 | APAF1 (0.40) | EGFRMEN1KMT2APOLBCASP6 | |
| SCHEMBL2626785 | 0.78 | TERT (0.44) | EGFRMEN1KMT2APOLBCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170273986-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2017-09-28 | — | — | US | disclosed |
| US-20170273986-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2017-09-28 | — | — | US | disclosed |
| US-20170267652-A1 | PROCESS FOR THE PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | EUPHARMA PTY LTD (AU) | 2017-09-21 | — | — | US | disclosed |
| US-20170267652-A1 | PROCESS FOR THE PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | EUPHARMA PTY LTD (AU) | 2017-09-21 | — | — | US | disclosed |
| US-9701648-B2 | Process for the purification of diaminophenothiazinium compounds | EUPHARMA PTY LTD (AU) | 2017-07-11 | — | — | US | disclosed |
| US-9701648-B2 | Process for the purification of diaminophenothiazinium compounds | EUPHARMA PTY LTD (AU) | 2017-07-11 | — | — | US | disclosed |
| US-9675621-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2017-06-13 | — | — | US | disclosed |
| US-9675621-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2017-06-13 | — | — | US | disclosed |
| US-20160296531-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2016-10-13 | — | — | US | disclosed |
| US-20160200696-A1 | PROCESS FOR THE PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | EUPHARMA PTY LTD (AU) | 2016-07-14 | — | — | US | disclosed |
| US-8114595-B2 | Light emission modifiers and their uses in nucleic acid detection, amplification and analysis | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2012-02-14 | — | — | US | disclosed |
| US-7919242-B2 | Light emission modifiers and their uses in nucleic acid detection, amplification and analysis | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-20100279850-A1 | CHEMICALLY-RESISTANT COATING COMPOSITION | VENTANA RESEARCH CORPORATION | 2010-11-04 | — | — | US | disclosed |
| US-20100124744-A1 | DETECTION OF TARGET VARIANTS USING A FLUORESCENT LABEL AND A SOLUBLE QUENCHER | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2010-05-20 | — | — | US | disclosed |
| US-20100112622-A1 | METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN | ARKRAY, INC. (JP) | 2010-05-06 | — | — | US | disclosed |
| US-20100015630-A1 | Light Emission Modifiers and Their Uses in Nucleic Acid Detection, Amplification and Analysis | ROCHE MOLECULAR SYSTEM, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-20100015598-A1 | Light Emission Modifiers and Their Uses in Nucleic Acid Detection, Amplification and Analysis | ROCHE MOLECULAR SYSTEM, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-20100015629-A1 | Light Emission Modifiers and Their Uses in Nucleic Acid Detection, Amplification and Analysis | ROCHE MOLECULAR SYSTEM, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-20070254854-A1 | Aqueous Antiseptic Solution and Compatible Anionic Dye for Staining Skin | MEDI-FLEX, INC. (US) | 2007-11-01 | — | — | US | disclosed |
| US-20070020664-A1 | Light emission modifiers and their uses in nucleic acid detection, amplification and analysis | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170267652-A1 | PROCESS FOR THE PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | QDPR, DDC, DDT | EGFR 3335/4885MEN1 823/4885KMT2A 1553/4885 |
| US-20070020664-A1 | Light emission modifiers and their uses in nucleic acid detection, amplification and analysis | POLRMT, POLL, DNTT | EGFR 2726/4885MEN1 2117/4885KMT2A 2968/4885 |
| US-20170273986-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | MB, TPMT, HBB | EGFR 2897/4885MEN1 330/4885KMT2A 936/4885 |
| US-20100015629-A1 | Light Emission Modifiers and Their Uses in Nucleic Acid Detection, Amplification and Analysis | POLRMT, POLL, DNTT | EGFR 2726/4885MEN1 2117/4885KMT2A 2968/4885 |
| US-20100112622-A1 | METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN | TH, TYR, HPD | EGFR 2653/4885MEN1 4351/4885KMT2A 2700/4885 |
| US-20100279850-A1 | CHEMICALLY-RESISTANT COATING COMPOSITION | DNMT1, VCL, DNMT3L | EGFR 403/4885MEN1 2522/4885KMT2A 648/4885 |
| US-20070254854-A1 | Aqueous Antiseptic Solution and Compatible Anionic Dye for Staining Skin | CUTA, IK, POLR1C | EGFR 773/4885MEN1 3908/4885KMT2A 2318/4885 |
| US-20160200696-A1 | PROCESS FOR THE PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | QDPR, MAOB, DDC | EGFR 2667/4885MEN1 1461/4885KMT2A 1025/4885 |
| US-20160296531-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | MB, TPMT, HBB | EGFR 2897/4885MEN1 330/4885KMT2A 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.