Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.39 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.32 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | BAX | Q07812 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28750687 | 0.94 | LTA4H (0.43) | LTA4HTSHRCA4KCNA3CA5A | |
| Lithium Ion SCHEMBL27588255 | 0.94 | LTA4H (0.43) | LTA4HTSHRCA4KCNA3CA5A | |
| Potassium Ion SCHEMBL27588259 | 0.94 | LTA4H (0.43) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL27588256 | 0.94 | LTA4H (0.43) | LTA4HTSHRCA4KCNA3CA5A | |
| Tetramethylammonium Ion SCHEMBL27606118 | 0.87 | CA4 (0.40) | LTA4HTSHRCA4KCNA3CA5A | |
| Potassium Ion SCHEMBL29139750 | 0.78 | LTA4H (0.43) | LTA4HTSHRCA4KCNA3CA5A | |
| Potassium Ion SCHEMBL9463083 | 0.74 | LTA4H (0.39) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL646525 | 0.73 | LTA4H (0.50) | LTA4HTSHRCA4KCNA3CA5A | |
| SCHEMBL301726 | 0.73 | LTA4H (0.50) | LTA4HTSHRCA4KCNA3CA5A | |
| Lithium Ion SCHEMBL7967683 | 0.72 | LTA4H (0.38) | LTA4HTSHRCA4KCNA3CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115896890-A | Micro-arc oxidation sealing aging treatment method for aluminum alloy plate | 安徽兆鑫铝业科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-113004193-B | Use of silicon compounds in cyclization reactions | 兰州康鹏威耳化工有限公司 | 2024-10-18 | — | — | CN | disclosed |
| WO-2024202626-A1 | ORGANOPOLYSILOXANE | 信越化学工業株式会社 | 2024-10-03 | — | — | WO | disclosed |
| WO-2024197844-A1 | METHOD FOR SURFACE MODIFICATION OF HIGH-NICKEL TERNARY POSITIVE ELECTRODE MATERIAL AND USE THEREOF | 广东邦普循环科技有限公司 | 2024-10-03 | — | — | WO | disclosed |
| CN-117964574-A | Preparation method of 5-chloromethyl-2-trifluoromethyl-1, 3, 4-oxadiazole | 兰州康鹏威耳化工有限公司 | 2024-05-03 | — | — | CN | disclosed |
| US-20240124401-A1 | USE OF SILICON COMPOUNDS IN CYCLIZATION REACTIONS | LANZHOU CHEMSPECWEIER CHEMICAL CO., LTD. (CN) | 2024-04-18 | — | — | US | disclosed |
| EP-4273128-A1 | USE OF SILICON COMPOUND IN CYCLIZATION REACTION | Lanzhou Chemspecweier Chemical Co., Ltd. (CN) | 2023-11-08 | — | — | EP | disclosed |
| CN-115896890-A | Micro-arc oxidation sealing aging treatment method for aluminum alloy plate | 安徽兆鑫铝业科技有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-1542071-A | Composition for forming porous film, porous film and method for forming the same, interlevel insulator film and semiconductor device | ��Խ��ѧ��ҵ��ʽ���� | 2004-11-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124401-A1 | USE OF SILICON COMPOUNDS IN CYCLIZATION REACTIONS | SIRT5, HDAC5, HDAC2 | CA4 4/4885CA1 21/4885CA2 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.