Ethyl Acetate

Ethyl Acetate

SCHEMBL2764170

CC#N.CCOC(C)=O.O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Ethyl Acetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 known ✓ O00255 2/20 0.42
CHRM2 known ✓ P08172 1/20 0.36
CHRM4 known ✓ P08173 1/20 0.36
HTR1A known ✓ P08908 1/20 0.36
CHRM5 known ✓ P08912 1/20 0.36
CHRM1 known ✓ P11229 1/20 0.36
CHRM3 known ✓ P20309 1/20 0.36
ALDH1A1 P00352 7/20 0.74
LMNA P02545 1/20 0.74
HSD17B10 Q99714 1/20 0.74
TSHR P16473 2/20 0.46
KMT2A Q03164 2/20 0.42
ALOX15 P16050 1/20 0.42
MGAM O43451 1/20 0.42
GAA P10253 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
SOAT1 P35610 1/20 0.42
CYP2C9 P11712 1/20 0.39
TRPA1 O75762 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Acetate SCHEMBL2336202 1.00 ALDH1A1 (0.74) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL390477 1.00
Ethyl Acetate SCHEMBL5862364 1.00 ALDH1A1 (0.74) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL10517706 0.97 ALDH1A1 (0.70) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL4048106 0.97 ALDH1A1 (0.70) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL2010629 0.97 ALDH1A1 (0.70) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL5502461 0.97 ALDH1A1 (0.70) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL9131985 0.95 ALDH1A1 (0.67) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL7382473 0.95 ALDH1A1 (0.67) ALDH1A1LMNAHSD17B10TSHRMEN1
Ethyl Acetate SCHEMBL29038936 0.95 ALDH1A1 (0.67) ALDH1A1LMNAHSD17B10TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114280201-B Efficient separation method of polyphenol components in dandelion 山东省千佛山医院 2023-06-13 CN claimed
CN-114280201-A Efficient separation method for polyphenol components in dandelion 山东省千佛山医院 2022-04-05 CN claimed
US-20180057481-A1 SOLID FORMS OF CENICRIVIROC MESYLATE AND PROCESSES OF MAKING SOLID FORMS OF CENICRIVIROC MESYLATE TOBIRA THERAPEUTICS, INC. 2018-03-01 US claimed
CN-100486970-C Preparation method of racemic homocitric acid lactone UNIV XIAMEN (CN) 2009-05-13 CN claimed
CN-1948299-A Preparation method of racemic homocitric acid lactone XIAMEN UIV (CN) 2007-04-18 CN claimed
CN-114280201-B Efficient separation method of polyphenol components in dandelion 山东省千佛山医院 2023-06-13 CN disclosed
CN-114280201-B Efficient separation method of polyphenol components in dandelion 山东省千佛山医院 2023-06-13 CN disclosed
US-20220204481-A1 PROTEIN AND/OR PEPTIDE MODIFICATION MOLECULE OSAKA UNIVERSITY (JP) 2022-06-30 US disclosed
CN-114280201-A Efficient separation method for polyphenol components in dandelion 山东省千佛山医院 2022-04-05 CN disclosed
CN-114280201-A Efficient separation method for polyphenol components in dandelion 山东省千佛山医院 2022-04-05 CN disclosed
EP-3932912-A1 PROTEIN AND/OR PEPTIDE MODIFICATION MOLECULE Osaka University (JP) 2022-01-05 EP disclosed
CN-113185406-A Efficient preparation method of phenolic acid active ingredients in salvia yunnanensis 山东省分析测试中心 2021-07-30 CN disclosed
CN-1948299-A Preparation method of racemic homocitric acid lactone XIAMEN UIV (CN) 2007-04-18 CN disclosed
US-20060199826-A1 Cyclopropane compounds and pharmaceutical use thereof JAPAN TOBACCO INC. (JP) 2006-09-07 US disclosed
US-20050222146-A1 N-substituted-n-sulfonylaminocyclopropane compounds and pharmaceutical use thereof JAPAN TOBACCO INC. (JP) 2005-10-06 US disclosed
US-4013707-A PROSTAGLANDINS, ANTISPASMODIC, ANTIASTHMA, HYPOTENSIVE THE UPJOHN COMPANY (US) 1977-03-22 US disclosed
US-4013693-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1977-03-22 US disclosed
US-3969464-A PROSTAGLANDIN THE UPJOHN COMPANY (US) 1976-07-13 US disclosed
US-3952048-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-04-20 US disclosed
US-3948970-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060199826-A1 Cyclopropane compounds and pharmaceutical use thereof MMP13, MMP9, MMP11 MEN1 1818/4885CHRM2 213/4885CHRM4 1067/4885
US-20220204481-A1 PROTEIN AND/OR PEPTIDE MODIFICATION MOLECULE PTMS, DNPEP, NPPA MEN1 496/4885CHRM2 4280/4885CHRM4 4289/4885
US-20050222146-A1 N-substituted-n-sulfonylaminocyclopropane compounds and pharmaceutical use thereof MMP13, MMP11, MMP1 MEN1 1233/4885CHRM2 138/4885CHRM4 758/4885
US-20180057481-A1 SOLID FORMS OF CENICRIVIROC MESYLATE AND PROCESSES OF MAKING SOLID FORMS OF CENICRIVIROC MESYLATE TYMP, MTAP, TYMS MEN1 915/4885CHRM2 4380/4885CHRM4 3704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.