Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308587 | 0.98 | HTR7 (0.41) | HTR7PSMD14HSP90AA1MMP2MC4R | |
| Lithium Ion SCHEMBL8757202 | 0.96 | HTR7 (0.40) | HTR7PSMD14HSP90AA1MMP2MC4R | |
| SCHEMBL6428385 | 0.96 | HTR7 (0.40) | HTR7PSMD14HSP90AA1MMP2MC4R | |
| SCHEMBL18036988 | 0.90 | PSMD14 (0.42) | HTR7PSMD14HSP90AA1MMP2MC4R | |
| Tetrabuthylammonium SCHEMBL18036963 | 0.82 | PSMD14 (0.44) | HTR7PSMD14HSP90AA1MMP2MC4R | |
| SCHEMBL8757622 | 0.81 | HTR7 (0.31) | HTR7HDAC3HDAC1HDAC2 | |
| SCHEMBL307072 | 0.78 | HTT (0.38) | HPGDTSHRACHELMNA | |
| SCHEMBL5078343 | 0.78 | TSHR (0.37) | TP53TSHR | |
| SCHEMBL8757415 | 0.77 | SMN1; SMN2 (0.40) | MMP2HPGDHDAC3HDAC1HDAC2 | |
| SCHEMBL8757360 | 0.77 | CYP1A2 (0.39) | HDAC3HDAC1HDAC2TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216349-B1 | USE OF A PHENOL TYPE COMPOUND IN A DENTAL CHEMICAL POLYMERIZATION CATALYST WITH IMPROVED POLYMERIZING ACTIVITY | TOKUYAMA DENTAL CORP (JP) | 2023-09-20 | — | — | EP | disclosed |
| US-20100304961-A1 | DENTAL CHEMICAL POLYMERIZATION CATALYST AND DENTAL CURABLE COMPOSITION CONTAINING THE SAME CATALYST | TOKUYAMA DENTAL CORPORATION (JP) | 2010-12-02 | — | — | US | disclosed |
| EP-1249221-B1 | DENTAL ADHESIVE COMPOSITION | TOKUYAMA DENTAL CORP (JP) | 2010-10-13 | — | — | EP | disclosed |
| EP-2216349-A1 | CHEMICAL POLYMERIZATION CATALYST FOR DENTAL USE AND CURABLE DENTAL COMPOSITIONS CONTAINING THE CATALYST | Tokuyama Dental Corporation (JP) | 2010-08-11 | — | — | EP | disclosed |
| US-20100120941-A1 | ADHESIVE AGENT FOR ADHESION BETWEEN ALGINATE IMPRESSION MATERIAL FOR DENTAL APPLICATIONS AND IMPRESSION TRAY, AND KIT COMPRISING THE ADHESIVE AGENT | TOKUYAMA DENTAL CORPORATION (JP) | 2010-05-13 | — | — | US | disclosed |
| EP-2127631-A1 | ADHESIVE AGENT FOR ADHESION BETWEEN ALGINATE IMPRESSION MATERIAL FOR DENTAL APPLICATIONS AND IMPRESSION TRAY, AND KIT COMPRISING THE ADHESIVE AGENT | Tokuyama Dental Corporation (JP) | 2009-12-02 | — | — | EP | disclosed |
| US-7084182-B2 | Photopolymerization initiator | TOKUYAMA CORPORATION (JP) | 2006-08-01 | — | — | US | disclosed |
| EP-1457190-B1 | Photopolymerization initiator | TOKUYAMA CORP (JP) | 2006-06-21 | — | — | EP | disclosed |
| US-20040180983-A1 | Photopolymerization initiator | TOKUYAMA DENTAL CORPORATION (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1457190-A1 | Photopolymerization initiator | Tokuyama Corporation (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6759449-B2 | NONCROSSLINKING POLYMETHYL METHACRYLATE AND POLYETHYL METH-ACRYLATE SPHERICAL FILLER, UNSATURATED ACID FUNCTIONALIZED MONOMER AND POLYMERIZATION INITIATOR | TOKUYAMA DENTAL CORPORATION (JP) | 2004-07-06 | — | — | US | disclosed |
| US-20030050359-A1 | Dental adhesive composition | TOKUYAMA DENTAL CORPORATION (JP) | 2003-03-13 | — | — | US | disclosed |
| EP-1249221-A1 | DENTAL ADHESIVE COMPOSITION | Tokuyama Dental Corporation (JP) | 2002-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030050359-A1 | Dental adhesive composition | CAD, ASIC1, CD44 | HTR7 2116/4885PSMD14 3345/4885HSP90AA1 2550/4885 |
| US-20100120941-A1 | ADHESIVE AGENT FOR ADHESION BETWEEN ALGINATE IMPRESSION MATERIAL FOR DENTAL APPLICATIONS AND IMPRESSION TRAY, AND KIT COMPRISING THE ADHESIVE AGENT | ICAM1, ITGB8, TRA2B | HTR7 602/4885PSMD14 2924/4885HSP90AA1 3591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.