SCHEMBL2808762

SCHEMBL2808762

Cc1cccc(N(CC(=O)O)CC(=O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
RAB9A P51151 4/20 0.48
NPC1 O15118 3/20 0.48
PAX8 Q06710 2/20 0.48
JAK2 O60674 1/20 0.48
HTT P42858 1/20 0.48
HSD17B10 Q99714 1/20 0.47
HSD17B1 P14061 2/20 0.43
HSD17B2 P37059 2/20 0.43
TSHR P16473 1/20 0.43
TP53 P04637 1/20 0.42
GPX4 P36969 1/20 0.42
HPGD P15428 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
PTGIR P43119 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13645027 0.92 ALOX15 (0.46) ALDH1A1RAB9ANPC1PAX8JAK2
SCHEMBL28549745 0.91 ALDH1A1 (0.47) ALDH1A1RAB9ANPC1PAX8JAK2
SCHEMBL13603837 0.89 TSHR (0.42) ALDH1A1RAB9ANPC1PAX8JAK2
SCHEMBL13645033 0.89 POLB (0.43) ALDH1A1RAB9ANPC1PAX8JAK2
SCHEMBL13644991 0.87 GAA (0.44) ALDH1A1RAB9ANPC1PAX8JAK2
SCHEMBL340808 0.86 CRHBP (0.47) ALDH1A1RAB9ANPC1HTTTSHR
SCHEMBL13644988 0.85 POLB (0.54) ALDH1A1RAB9ANPC1HTTTSHR
SCHEMBL19334460 0.84 ALDH1A1 (0.47) ALDH1A1RAB9ANPC1PAX8JAK2
SCHEMBL11339632 0.82 ALDH1A1 (0.49) ALDH1A1RAB9ANPC1PAX8JAK2
SCHEMBL9779999 0.82 ALDH1A1 (0.46) ALDH1A1RAB9ANPC1PAX8JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 EP disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
WO-2022047081-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE HENRY DEREK (US) 2022-03-03 WO disclosed
US-20210346261-A1 HAIR LIGHTENING COMPOSITIONS AND METHODS OF USE L'OREAL (FR) 2021-11-11 US disclosed
US-11135150-B2 Compositions and methods for improving the quality of chemically treated hair L'OREAL (FR) 2021-10-05 US disclosed
WO-2018128678-A2 COMPOSITIONS AND METHODS FOR RESTRUCTURING CHEMICALLY TREATED HAIR L'OREAL (FR) 2018-07-12 WO disclosed
WO-2018119500-A1 VISCOELASTIC COSMETIC COMPOSITIONS L'OREAL (FR) 2018-07-05 WO disclosed
WO-2018093575-A1 COMPOSITIONS AND METHODS FOR IMPROVING THE QUALITY OF CHEMICALLY TREATED HAIR L'OREAL (FR) 2018-05-24 WO disclosed
US-8624022-B2 Substituted aniline derivatives UCB PHARMA, S.A. (BE) 2014-01-07 US disclosed
US-20120029188-A1 Substituted Aniline Derivatives UCB PHARMA S.A. (BE) 2012-02-02 US disclosed
US-8071582-B2 Substituted aniline derivatives UCB PHARMA S.A. (BE) 2011-12-06 US disclosed
US-20110014271-A1 Substituted Aniline Derivatives UCB PHARMA S.A. (BE) 2011-01-20 US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
US-20090246700-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090246700-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029188-A1 Substituted Aniline Derivatives NAT1, DPM1, IL4I1 ALDH1A1 469/4885RAB9A 3725/4885NPC1 599/4885
US-11135150-B2 Compositions and methods for improving the quality of chemically treated hair SRM, TET2, TET3 ALDH1A1 824/4885RAB9A 4553/4885NPC1 4843/4885
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 ALDH1A1 1901/4885RAB9A 4090/4885NPC1 4765/4885
US-20210346261-A1 HAIR LIGHTENING COMPOSITIONS AND METHODS OF USE TYR, ALAD, CYBA ALDH1A1 448/4885RAB9A 4315/4885NPC1 4854/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB ALDH1A1 4765/4885RAB9A 4503/4885NPC1 3829/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA ALDH1A1 1510/4885RAB9A 4824/4885NPC1 3993/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA ALDH1A1 448/4885RAB9A 4315/4885NPC1 4854/4885
US-20110014271-A1 Substituted Aniline Derivatives NAT1, DPM1, IL4I1 ALDH1A1 469/4885RAB9A 3725/4885NPC1 599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.