Acrylic Acid

Acrylic Acid

SCHEMBL28294518

C=CC(=O)O.O=S(=O)([O-])C=Cc1ccccc1.[Na+]

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG known ✓ P37231 3/20 0.42
HDAC3 O15379 2/20 0.46
HDAC4 P56524 2/20 0.46
HDAC1 Q13547 2/20 0.46
HDAC2 Q92769 2/20 0.46
HDAC8 Q9BY41 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
TNKS O95271 1/20 0.46
HCAR2 Q8TDS4 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
TNKS2 Q9H2K2 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46
HTT P42858 1/20 0.43
LMNA P02545 4/20 0.42
NFE2L2 Q16236 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL16564294 0.97 HDAC3 (0.46) HDAC3HDAC4HDAC1HDAC2HDAC8
Acrylic Acid SCHEMBL6279451 0.92 HTT (0.42) HDAC3HDAC4HDAC1HDAC2HDAC8
Acrylamide SCHEMBL9325809 0.90 HTT (0.41) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL28223837 0.89 PPARG (0.44) HDAC3HDAC4HDAC1HDAC2HDAC8
Maleic Acid SCHEMBL27753546 0.88 HDAC3 (0.57) HDAC3HDAC4HDAC1HDAC2HDAC8
Fumaric Acid SCHEMBL8655504 0.88 HDAC3 (0.57) HDAC3HDAC4HDAC1HDAC2HDAC8
Maleic Acid SCHEMBL4270458 0.88 HDAC3 (0.57) HDAC3HDAC4HDAC1HDAC2HDAC8
Butadiene SCHEMBL28640925 0.87 PPARG (0.46) HTTLMNAPPARGNFE2L2KMT2A
Butadiene SCHEMBL10352729 0.87 PPARG (0.46) HTTLMNAPPARGNFE2L2KMT2A
Vinylsulfonic Acid SCHEMBL29204743 0.87 PPARG (0.46) HTTLMNAPPARGNFE2L2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113501902-B Preparation method of styrene-acrylic acid copolymer type dispersing agent 四川东材科技集团股份有限公司 2023-08-18 CN claimed
CN-113501902-A Preparation method of styrene-acrylic acid copolymerization type dispersing agent 四川东材科技集团股份有限公司 2021-10-15 CN claimed
CN-119528472-B Retarder for high-temperature-resistant high-strength cement paste and preparation method thereof 中国石油天然气集团有限公司 2025-12-02 CN disclosed
CN-119528472-A Retarder for high-temperature-resistant high-strength cement paste and preparation method thereof 中国石油天然气集团有限公司 2025-02-28 CN disclosed
CN-113501902-B Preparation method of styrene-acrylic acid copolymer type dispersing agent 四川东材科技集团股份有限公司 2023-08-18 CN disclosed
CN-113501902-A Preparation method of styrene-acrylic acid copolymerization type dispersing agent 四川东材科技集团股份有限公司 2021-10-15 CN disclosed
CN-109627857-A Traffic paint vehicle composite 罗门哈斯公司 2019-04-16 CN disclosed