Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.38 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.38 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.38 |
| ▸ | P2RY4 known ✓ | P51582 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 5/20 | 0.40 |
| ▸ | MMP13 | P45452 | 5/20 | 0.40 |
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | MMP14 | P50281 | 3/20 | 0.40 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | MMP16 | P51512 | 2/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 3/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29512262 | 0.79 | MMP12 (0.45) | MMP12MMP13MMP1MMP2MMP3 | |
| SCHEMBL29538686 | 0.77 | RAD51 (0.38) | MMP12MMP13MMP1MMP2MMP3 | |
| SCHEMBL10865908 | 0.77 | RAD51 (0.40) | MMP12MMP13MMP1MMP2MMP3 | |
| SCHEMBL39171 | 0.77 | TAAR1 (0.45) | RAD51CA1CA2CA9CA12 | |
| SCHEMBL5267610 | 0.77 | P2RY4 (0.39) | RAD51CA2CA9CA12P2RY4 | |
| SCHEMBL28530830 | 0.75 | MMP2 (0.40) | MMP12MMP13MMP1MMP2MMP3 | |
| SCHEMBL29409221 | 0.74 | LIPG (0.43) | RAD51CA2CA9CA12P2RY4 | |
| SCHEMBL2138603 | 0.74 | LIPG (0.43) | RAD51CA2CA9CA12P2RY4 | |
| SCHEMBL1058401 | 0.74 | CTSB (0.50) | CA2CA9CA12P2RY4 | |
| Potassium Ion SCHEMBL23749118 | 0.73 | CTSB (0.39) | RAD51CA2CA9CA12P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511887-A | Integrated laundry detergent article | 宝洁公司 | 2020-08-07 | — | — | CN | claimed |
| CN-111511887-A | Integrated laundry detergent article | 宝洁公司 | 2020-08-07 | — | — | CN | disclosed |