Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GALK1 | P51570 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913166 | 0.84 | XDH (0.38) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1530329 | 0.83 | MAPT (0.45) | MAPTPOLBTP53ALDH1A1GAA | |
| SCHEMBL2910190 | 0.83 | GPR27 (0.42) | MEN1KMT2A | |
| SCHEMBL2907832 | 0.80 | BCL2L1 (0.34) | POLB | |
| SCHEMBL2913154 | 0.80 | BCL2L1 (0.35) | POLBALDH1A1HPGD | |
| SCHEMBL2912963 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL2915315 | 0.79 | KIF18A (0.35) | POLB | |
| SCHEMBL2910683 | 0.78 | ALDH1A1 (0.36) | MAPTALDH1A1GAALMNATSHR | |
| SCHEMBL2910962 | 0.78 | RAB9A (0.39) | MAPTPOLBTP53ALDH1A1HSD17B10 | |
| SCHEMBL2913374 | 0.77 | BCL2L1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |