Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | G6PD | P11413 | 2/20 | 0.36 |
| ▸ | MC4R | P32245 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2915249 | 0.91 | ITGA4 (0.39) | ITGA4L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL2915315 | 0.86 | KIF18A (0.35) | ITGA4L3MBTL1POLB | |
| SCHEMBL1530680 | 0.84 | ALDH1A1 (0.38) | ITGA4L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL2913154 | 0.84 | BCL2L1 (0.35) | ITGA4L3MBTL1ALDH1A1POLBCA1 | |
| SCHEMBL2907832 | 0.84 | BCL2L1 (0.34) | ITGA4L3MBTL1POLB | |
| SCHEMBL2913166 | 0.83 | XDH (0.38) | ITGA4L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL2910190 | 0.80 | GPR27 (0.42) | MEN1KMT2A | |
| SCHEMBL2913374 | 0.80 | BCL2L1 (0.36) | ITGA4L3MBTL1ALDH1A1TRPV4CA1 | |
| SCHEMBL2912963 | 0.79 | ALDH1A1 (0.42) | ITGA4L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL2910683 | 0.78 | ALDH1A1 (0.36) | ITGA4L3MBTL1MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |