Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181923 | 1.00 | NPC1 (0.44) | NPC1RAB9AKMT2AMEN1PRCP | |
| SCHEMBL3053970 | 0.98 | GAA (0.42) | NPC1RAB9AKMT2AMEN1PRCP | |
| SCHEMBL2048093 | 0.93 | — | — | |
| SCHEMBL2635747 | 0.88 | — | — | |
| SCHEMBL19035612 | 0.82 | NCF1 (0.45) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL8204298 | 0.80 | PKM (0.34) | NPC1RAB9AKMT2AMEN1PRCP | |
| SCHEMBL17198007 | 0.80 | ALDH1A1 (0.46) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL6345668 | 0.78 | HTT (0.52) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL1035325 | 0.78 | MAPT (0.34) | NPC1RAB9AKMT2AMEN1PRCP | |
| SCHEMBL4328483 | 0.78 | ADRB1 (0.47) | SIGMAR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199882-A1 | THIENYL-DIBENZOAZEPINES AND THEIR DERIVATIVES AS DONORS FOR XANTHENE-BASED SHORT-WAVE INFRARED (SWIR) DYES | MISSISSIPPI STATE UNIVERSITY (US) | 2024-06-20 | — | — | US | claimed |
| US-20240124714-A1 | NEAR INFRARED DYES FOR BIOLOGICAL IMAGING AND OPTOELECTRONIC DEVICES | MISSISSIPPI STATE UNIVERSITY (US) | 2024-04-18 | — | — | US | claimed |
| CN-111909167-B | Piperidinothiophene derivative and application thereof in preparation of medicine for treating psoriasis | 华东师范大学 | 2021-11-19 | — | — | CN | claimed |
| US-11130766-B2 | Deuterated thienopiperidine derivatives, manufacturing method, and application thereof | JIANGSU TASLY DIYI PHARMACEUTICAL CO., LTD. (CN) | 2021-09-28 | — | — | US | claimed |
| US-20210179632-A1 | THIENOPIPERIDINE DERIVATIVE AND USE THEREOF | JIANGSU TASLY DIYI PHARMACEUTICAL CO LTD (CN) | 2021-06-17 | — | — | US | claimed |
| CN-111909167-A | Novel piperidinothiophene derivative and application thereof in preparing medicine for treating psoriasis | 华东师范大学 | 2020-11-10 | — | — | CN | claimed |
| CN-108191885-B | Piperidinothiophene micromolecule organic compound and application thereof | 华东师范大学 | 2020-08-04 | — | — | CN | claimed |
| EP-3048108-B1 | THIENOPIPERIDINE DERIVATIVE AND USE THEREOF | JIANGSU TASLY DIYI PHARMACEUTICAL CO LTD (CN) | 2020-07-15 | — | — | EP | claimed |
| CN-107922448-B | Deuterated thienopiperidine derivative, preparation method and application thereof | 江苏天士力帝益药业有限公司 | 2020-06-12 | — | — | CN | claimed |
| CN-110981912-A | Phosphoric acid triester DOPO derivative flame retardant and preparation method thereof | 寿光卫东化工有限公司 | 2020-04-10 | — | — | CN | claimed |
| EP-2069301-B1 | PROCESS FOR THE PREPARATION OF PLEUROMUTILINS | NABRIVA THERAPEUTICS AG (AT) | 2011-09-07 | — | — | EP | claimed |
| EP-2336315-A2 | Enzymatic encoding methods for efficient synthesis of large libraries | Nuevolution A/S (DK) | 2011-06-22 | — | — | EP | claimed |
| EP-2272829-A2 | Process for the preparation of pleuromutilins | Nabriva Therapeutics AG (AT) | 2011-01-12 | — | — | EP | claimed |
| US-20090253748-A1 | PROCESS FOR THE PREPARATION OF PLEUROMUTILINS | NABRIVA THERAPEUTICS AG (AT) | 2009-10-08 | — | — | US | claimed |
| EP-2106260-A1 | INSULIN SENSITISERS AND METHODS OF TREATMENT | Verva Pharmaceuticals Ltd (AU) | 2009-10-07 | — | — | EP | claimed |
| EP-2069301-A1 | PROCESS FOR THE PREPARATION OF PLEUROMUTILINS | Nabriva Therapeutics Forschungs GmbH (AT) | 2009-06-17 | — | — | EP | claimed |
| WO-2008089521-A1 | INSULIN SENSITISERS AND METHODS OF TREATMENT | VERVA PHARMACEUTICALS LTD (AU) | 2008-07-31 | — | — | WO | claimed |
| WO-2008040043-A1 | PROCESS FOR THE PREPARATION OF PLEUROMUTILINS | NABRIVA THERAPEUTICS AG (AT) | 2008-04-10 | — | — | WO | claimed |
| EP-1908750-A1 | Process for the preparation of pleuromutilins | Nabriva Therapeutics Forschungs GmbH (AT) | 2008-04-09 | — | — | EP | claimed |
| US-20070275984-A1 | Novel Thieno-Pyridine and Thieno-Pyrimidine Derivatives and Their Use as Positive Allosteric Modulators of Mglur2-Receptors | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124714-A1 | NEAR INFRARED DYES FOR BIOLOGICAL IMAGING AND OPTOELECTRONIC DEVICES | SIGMAR1, HEATR1, CD209 | NPC1 2680/4885RAB9A 378/4885KMT2A 4519/4885 |
| US-20090253748-A1 | PROCESS FOR THE PREPARATION OF PLEUROMUTILINS | PLEC, MLN, PTMA | NPC1 4843/4885RAB9A 874/4885KMT2A 911/4885 |
| US-11130766-B2 | Deuterated thienopiperidine derivatives, manufacturing method, and application thereof | DHPS, QDPR, TBXA2R | NPC1 1501/4885RAB9A 2265/4885KMT2A 2222/4885 |
| US-20210179632-A1 | THIENOPIPERIDINE DERIVATIVE AND USE THEREOF | TBXA2R, PF4, P2RY4 | NPC1 2587/4885RAB9A 1039/4885KMT2A 2689/4885 |
| US-20070275984-A1 | Novel Thieno-Pyridine and Thieno-Pyrimidine Derivatives and Their Use as Positive Allosteric Modulators of Mglur2-Receptors | GRM2, GRIA2, GRM1 | NPC1 3777/4885RAB9A 1976/4885KMT2A 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.