SCHEMBL29358622

SCHEMBL29358622

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)C(C)(C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NC(C)(C)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O)C(C)C

nearest known ligand 0.82

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 15/20 0.82
▸ NR3C1 P04150 5/20 0.81
▸ ECE1 P42892 1/20 0.78
▸ MUS81 Q96NY9 1/20 0.78
▸ CCKBR P32239 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29360422 0.96 GLP1R (0.88) GLP1RNR3C1ECE1MUS81CCKBR
SCHEMBL29366649 0.94 GLP1R (0.88) GLP1RNR3C1ECE1MUS81CCKBR
SCHEMBL29462206 0.94 GLP1R (0.88) GLP1RNR3C1ECE1MUS81CCKBR
SCHEMBL2899791 0.94 GLP1R (0.87) GLP1R
Glp-1 SCHEMBL29353361 0.93 GLP1R (0.89) GLP1RNR3C1ECE1MUS81CCKBR
SCHEMBL31060658 0.93 GLP1R (0.89) GLP1RNR3C1ECE1MUS81CCKBR
SCHEMBL30683162 0.92 GLP1R (0.81) GLP1RNR3C1ECE1MUS81CCKBR
SCHEMBL31087751 0.91 GLP1R (0.91) GLP1R
SCHEMBL31406268 0.91 GLP1R (0.91) GLP1R
SCHEMBL31406271 0.91 GLP1R (0.91) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025054607-A1 COMPOSITIONS AND METHODS FOR TREATING SARCOPENIA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-03-13 — — WO claimed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
EP-4735449-A1 TETRACYCLIC COMPOUNDS CONTAINING A FUSED INDOLE FOR TREATING APOL1-MEDIATED CHRONIC KIDNEY DISEASE OmniAB, Inc. (US) 2026-05-06 — — EP disclosed
EP-4727552-A2 PASSIVE PERMEABLE PCSK9 ANTAGONIST COMPOUNDS Merck Sharp & Dohme LLC (US) 2026-04-22 — — EP disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
US-12577259-B2 PCSK9 antagonist compounds MERCK SHARP & DOHME LLC (US) 2026-03-17 — — US disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 — — US disclosed
EP-4705296-A1 HETEROARYLINDOLE INHIBITORS OF APOL-1 OmniAB, Inc. (US) 2026-03-11 — — EP disclosed
EP-3558298-B1 ANTIDIABETIC SPIROCHROMAN COMPOUNDS MERCK SHARP & DOHME LLC (US) 2026-03-11 — — EP disclosed
EP-3966201-A1 THIOSEMICARBAZATES AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
CN-114126619-A Compounds for the synthesis of peptidomimetics 范因斯坦医学研究院 2022-03-01 — — CN disclosed
CN-106573966-B Compositions and methods for treating metabolic abnormalities NGM生物制药有限公司 2022-03-01 — — CN disclosed
US-20220049275-A1 SSI CELLS WITH PREDICTABLE AND STABLE TRANSGENE EXPRESSION AND METHODS OF FORMATION LONZA AG (CH) 2022-02-17 — — US disclosed
US-11248031-B2 Methods of treating diseases associated with fibrosis using modified FGF-21 polypeptides BRISTOL-MYERS SQUIBB COMPANY (US) 2022-02-15 — — US disclosed
US-20220042064-A1 CARBON-SOURCE REGULATED PROTEIN PRODUCTION IN A RECOMBINANT HOST CELL LONZA LTD (CH) 2022-02-10 — — US disclosed
EP-3947695-A1 MUT- METHYLOTROPHIC YEAST Universität für Bodenkultur Wien (AT) 2022-02-09 — — EP disclosed
CN-114026239-A MUT-methanol nutritional yeast 维也纳自然资源与生命科学大学 2022-02-08 — — CN disclosed
US-11236520-B2 Customizable facility LONZA LTD (CH) 2022-02-01 — — US disclosed
EP-3942014-A1 CONTINUOUS BLADE IMPELLER Lonza Ltd. (CH) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS GLP1R 319/4885NR3C1 785/4885ECE1 4008/4885
US-11248031-B2 Methods of treating diseases associated with fibrosis using modified FGF-21 polypeptides FGF1, HDGF, FGF2 GLP1R 432/4885NR3C1 1782/4885ECE1 1267/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 GLP1R 116/4885NR3C1 274/4885ECE1 1571/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 GLP1R 139/4885NR3C1 266/4885ECE1 3096/4885
US-12577259-B2 PCSK9 antagonist compounds PCSK9, LDLR, PCSK6 GLP1R 22/4885NR3C1 143/4885ECE1 713/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT GLP1R 228/4885NR3C1 128/4885ECE1 3527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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