SCHEMBL29360474

SCHEMBL29360474

CN1C(=O)CN=C(c2ccccc2)c2cc(Br)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 7/20 1.00
GABRA5 P31644 7/20 1.00
GABRA2 P47869 7/20 1.00
GABRG2 P18507 6/20 1.00
GABRB3 P28472 6/20 1.00
GABRA3 P34903 6/20 1.00
GABRB2 P47870 5/20 1.00
GABRP O00591 1/20 0.73
GABRD O14764 1/20 0.73
CACNA1F O60840 1/20 0.73
ALB P02768 1/20 0.73
GABRB1 P18505 1/20 0.73
OPRK1 P41145 1/20 0.73
AKR1C3 P42330 1/20 0.73
GABRA4 P48169 1/20 0.73
AKR1C2 P52895 1/20 0.73
GABRE P78334 1/20 0.73
CACNA1D Q01668 1/20 0.73
AKR1C1 Q04828 1/20 0.73
KCNH2 Q12809 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11681384 1.00 GABRA1 (1.00) GABRA1GABRA5GABRA2GABRG2GABRB3
SCHEMBL1368246 0.90 GABRA1 (0.81) GABRA1GABRA5GABRA2GABRG2GABRB3
SCHEMBL24194446 0.85 GABRA1 (0.74) GABRA1GABRA5GABRA2GABRG2GABRB3
SCHEMBL26648808 0.85 GABRA1 (0.73) GABRA1GABRA5GABRA2GABRG2GABRB3
SCHEMBL31695994 0.85 GABRA1 (0.73) GABRA1GABRA5GABRA2GABRG2GABRB3
Diazepam SCHEMBL1019217 0.84 GABRA1 (1.00) GABRA1GABRA5GABRA2GABRG2GABRB3
Diazepam SCHEMBL29362687 0.84 GABRA1 (1.00) GABRA1GABRA5GABRA2GABRG2GABRB3
Diazepam SCHEMBL21442 0.84 GABRA1 (1.00) GABRA1GABRA5GABRA2GABRG2GABRB3
SCHEMBL2928346 0.84 GABRA1 (0.73) GABRA1GABRA5GABRA2GABRG2GABRB3
SCHEMBL2925930 0.84 GABRA1 (0.73) GABRA1GABRA5GABRA2GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112739702-B Compound and organic electroluminescent element 出光兴产株式会社 2024-12-06 CN claimed
CN-116535485-A Keratin BD-8, its preparation method, its pharmaceutical composition and use 中国医学科学院药物研究所 2023-08-04 CN claimed
WO-2023096387-A1 NOVEL ORGANIC ANTHRACENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 에스에프씨 주식회사 2023-06-01 WO claimed
WO-2023096399-A1 HIGH EFFICIENCY AND LONG LIFETIME ORGANIC LIGHT-EMITTING DIODE 에스에프씨 주식회사 2023-06-01 WO claimed
CN-112118455-B Encoding and decoding method, device and equipment 杭州海康威视数字技术股份有限公司 2022-05-31 CN claimed
EP-3989576-A1 ENCODING AND DECODING METHOD AND APPARATUS, AND DEVICE THEREFOR Hangzhou Hikvision Digital Technology Co., Ltd. (CN) 2022-04-27 EP claimed
CN-115834903-B Inter-frame prediction method and device HUAWEI TECHNOLOGIES CO.,LTD. (CN) 2026-05-26 CN disclosed
EP-4746411-A2 COMPLEXITY REDUCTION AND BIT-WIDTH CONTROL FOR BI-DIRECTIONAL OPTICAL FLOW InterDigital VC Holdings, Inc. (US) 2026-05-20 EP disclosed
EP-3854089-B1 COMPLEXITY REDUCTION AND BIT-WIDTH CONTROL FOR BI-DIRECTIONAL OPTICAL FLOW INTERDIGITAL VC HOLDINGS INC (US) 2026-05-13 EP disclosed
CN-116095314-B Integrated image shaping and video coding 杜比实验室特许公司 2026-05-12 CN disclosed
US-12615959-B2 Organic electroluminescence device and electronic apparatus provided with the same IDEMITSU KOSAN CO., LTD. (JP) 2026-04-28 US disclosed
US-20260114114-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOSITION FOR ORGANIC MATERIALS MERCK PATENT GMBH (DE) 2026-04-23 US disclosed
US-12559467-B2 Organic light emitting device LG CHEM, LTD. (KR) 2026-02-24 US disclosed
CN-114206879-A Compound and organic electroluminescent element 出光兴产株式会社 2022-03-18 CN disclosed
US-11277606-B2 Method for decoding a bitstream SHARP KABUSHIKI KAISHA (JP) 2022-03-15 US disclosed
US-11271164-B2 Compound, composition, organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD (JP) 2022-03-08 US disclosed
US-20220061324-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2022-03-03 US disclosed
CN-112088534-B Method, device and equipment for inter-frame prediction and storage medium 华为技术有限公司 2022-02-15 CN disclosed
US-20220038679-A1 COMPLEXITY REDUCTION AND BIT-WIDTH CONTROL FOR BI-DIRECTIONAL OPTICAL FLOW INTERDIGITAL VC HOLDINGS, INC. 2022-02-03 US disclosed
US-20220029099-A1 NOVEL COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12615959-B2 Organic electroluminescence device and electronic apparatus provided with the same RER1, RIF1, SCO2 GABRA1 2362/4885GABRA5 2993/4885GABRA2 3217/4885
US-20260114114-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOSITION FOR ORGANIC MATERIALS LEF1, AP2A1, CACNA2D1 GABRA1 1695/4885GABRA5 2258/4885GABRA2 1771/4885
US-20220061324-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS DDT, ACHE, AADAC GABRA1 2660/4885GABRA5 2839/4885GABRA2 3403/4885
US-12559467-B2 Organic light emitting device CRY1, RPS24, ARL1 GABRA1 3752/4885GABRA5 4248/4885GABRA2 3939/4885
US-11271164-B2 Compound, composition, organic electroluminescent element and electronic device PAX2, CXXC4, XDH GABRA1 4254/4885GABRA5 3717/4885GABRA2 3317/4885
US-20220029099-A1 NOVEL COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS USING THE SAME RER1, RIF1, RPS19 GABRA1 2534/4885GABRA5 3850/4885GABRA2 3049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.