SCHEMBL29403553

SCHEMBL29403553

CC(C)=CCC/C(C)=C/CC[C@]1(C)Oc2c(c(O)cc3c2CN(CCC[C@@H](C(=O)O)N2Cc4c(cc(O)c5c4O[C@@](C)(CC/C=C(\C)CCC=C(C)C)[C@@H](O)C5)C2=O)C3=O)C[C@@H]1O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 8/20 0.36
▸ APP P05067 2/20 0.33
▸ PTPN1 P18031 1/20 0.33
▸ NR1H4 Q96RI1 2/20 0.32
▸ BACE1 P56817 1/20 0.32
▸ PSEN1 P49768 1/20 0.30
▸ PTGES O14684 1/20 0.30
▸ NR1I2 O75469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29381348 1.00 ALOX5 (0.36) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL30673511 1.00 ALOX5 (0.36) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL29725684 1.00 ALOX5 (0.36) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL30067164 1.00 ALOX5 (0.36) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL30678552 1.00 ALOX5 (0.36) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL24632196 1.00 ALOX5 (0.36) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL2624852 1.00 ALOX5 (0.36) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL31114965 1.00 ALOX5 (0.36) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL29330492 1.00 ALOX5 (0.36) ALOX5APPPTPN1NR1H4BACE1
SCHEMBL13663954 1.00 ALOX5 (0.36) ALOX5APPPTPN1NR1H4BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12453718-B2 Drug for treating or preventing cerebral hemorrhage, and method for treating or preventing cerebral hemorrhage using the drug CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) 2025-10-28 — — US claimed
US-20250099427-A1 Drug and Method of Treating or Preventing Renal Disease Using Drug SHOWA MEDICAL UNIVERSITY (JP) 2025-03-27 — — US claimed
US-12138244-B2 Drug and method of treating or preventing renal disease using drug SHOWA UNIVERSITY (JP) 2024-11-12 — — US claimed
US-20240238248-A1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING CEREBRAL INFARCTION CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) 2024-07-18 — — US claimed
US-20240238252-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) 2024-07-18 — — US claimed
CN-118084942-B Preparation method of methylated SMTP-7 深圳创元生物医药科技有限公司 2024-06-28 — — CN claimed
US-20240189280-A1 DRUG FOR TREATING OR PREVENTING CEREBRAL HEMORRHAGE, AND METHOD FOR TREATING OR PREVENTING CEREBRAL HEMORRHAGE USING THE DRUG CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) 2024-06-13 — — US claimed
CN-118084942-A Preparation method of methylated SMTP-7 深圳创元生物医药科技有限公司 2024-05-28 — — CN claimed
EP-4337193-A1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING CEREBRAL INFARCTION Biogen MA Inc. (US) 2024-03-20 — — EP claimed
EP-4326258-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 Biogen MA Inc. (US) 2024-02-28 — — EP claimed
CN-117295497-A Pharmaceutical composition for treating cerebral infarction 渤健马萨诸塞州股份有限公司 2023-12-26 — — CN claimed
US-11850232-B2 Drug for treating or preventing cerebral hemorrhage, and method for treating or preventing cerebral hemorrhage using the drug BIOGEN MA INC. (US) 2023-12-26 — — US claimed
EP-4252752-A1 DRUG FOR TREATMENT OR PREVENTION OF CEREBRAL HEMORRHAGE, AND METHOD FOR TREATMENT OR PREVENTION OF CEREBRAL HEMORRHAGE USING SAID DRUG Biogen MA Inc. (US) 2023-10-04 — — EP claimed
CN-116761600-A Medicament for treating or preventing cerebral hemorrhage and method for treating or preventing cerebral hemorrhage using the same 渤健马萨诸塞州股份有限公司 2023-09-15 — — CN claimed
US-RE49351-E1 Cytoprotective agent BIOGEN MA INC. (US) 2023-01-03 — — US claimed
WO-2022240810-A1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING CEREBRAL INFARCTION BIOGEN MA INC. (US) 2022-11-17 — — WO claimed
WO-2022226013-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 BIOGEN MA INC. (US) 2022-10-27 — — WO claimed
US-20220218664-A1 DRUG AND METHOD FOR TREATING OR PREVENTING COMPLICATIONS FROM DIABETES, USING SAID DRUG SHOWA UNIVERSITY (JP) 2022-07-14 — — US claimed
CN-114126711-A Medicament and method for treating or preventing diabetic complications using the same 学校法人昭和大学 2022-03-01 — — CN claimed
US-20260144792-A1 INHIBITORS OF CHYMASE FOR USE IN THE SELECTIVE RESOLUTION OF THROMBI IN THROMBOTIC OR THROMBOEMBOLIC DISORDERS SOCPRA SCIENCES SANTÉ HUMAINES S.E.C. (CA) 2026-05-28 — — US disclosed
CN-121620505-A SMTP-7 derivative and preparation method of intermediate thereof 上海森辉医药有限公司 2026-03-06 — — CN disclosed
CN-121620505-A SMTP-7 derivative and preparation method of intermediate thereof 上海森辉医药有限公司 2026-03-06 — — CN disclosed
WO-2026017006-A1 METHODS FOR PRODUCTION OF SMTP-7 AND INTERMEDIATES USED IN THE METHODS CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) 2026-01-22 — — WO disclosed
WO-2026017006-A1 METHODS FOR PRODUCTION OF SMTP-7 AND INTERMEDIATES USED IN THE METHODS CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) 2026-01-22 — — WO disclosed
CN-121064220-A SMTP-7 derivative and application thereof 福建盛迪医药有限公司 2025-12-05 — — CN disclosed
CN-121064221-A SMTP-7 derivative and application thereof 福建盛迪医药有限公司 2025-12-05 — — CN disclosed
CN-121064221-A SMTP-7 derivative and application thereof 福建盛迪医药有限公司 2025-12-05 — — CN disclosed
CN-121064220-A SMTP-7 derivative and application thereof 福建盛迪医药有限公司 2025-12-05 — — CN disclosed
US-12453718-B2 Drug for treating or preventing cerebral hemorrhage, and method for treating or preventing cerebral hemorrhage using the drug CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) 2025-10-28 — — US disclosed
US-20250302837-A1 INHIBITORS OF CHYMASE FOR USE IN THE SELECTIVE RESOLUTION OF THROMBI IN THROMBOTIC OR THROMBOEMBOLIC DISORDERS SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2025-10-02 — — US disclosed
CN-116669723-B SMTP-7 derivative and application thereof 福建盛迪医药有限公司 2025-09-09 — — CN disclosed
CN-116669723-B SMTP-7 derivative and application thereof 福建盛迪医药有限公司 2025-09-09 — — CN disclosed
CN-120192332-A Ring-fused compound, preparation method and application thereof 先声药业有限公司 2025-06-24 — — CN disclosed
US-20250177405-A1 METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS ASTROCYTE PHARMACEUTICALS, INC. 2025-06-05 — — US disclosed
US-20250179215-A1 PLASMIN-BINDING VHHS Rheinische Friedrich-Wilhelms-Universität Bonn (DE) 2025-06-05 — — US disclosed
WO-2025104204-A1 TREATMENT OF CARDIOVASCULAR DISEASES USING ANTI-HUMAN GPVI ANTIBODIES IN SUBPOPULATIONS OF SUBJECTS ACTICOR BIOTECH (FR) 2025-05-22 — — WO disclosed
EP-4556492-A1 TREATMENT OF CARDIOVASCULAR DISEASES USING ANTI-HUMAN GPVI ANTIBODIES IN SUBPOPULATIONS OF SUBJECTS Acticor Biotech (FR) 2025-05-21 — — EP disclosed
US-20250154252-A1 TREATMENT OF CARDIOVASCULAR DISEASES USING ANTI-HUMAN GPVI ANTIBODIES ACTICOR BIOTECH (FR) 2025-05-15 — — US disclosed
US-20250099427-A1 Drug and Method of Treating or Preventing Renal Disease Using Drug SHOWA MEDICAL UNIVERSITY (JP) 2025-03-27 — — US disclosed
EP-4519325-A1 PLASMIN-BINDING VHHS Rheinische Friedrich-Wilhelms-Universität Bonn (DE) 2025-03-12 — — EP disclosed
WO-2025031476-A1 PREPARATION METHOD FOR SMTP-7 DERIVATIVE AND INTERMEDIATE THEREOF 上海森辉医药有限公司 2025-02-13 — — WO disclosed
WO-2025031476-A1 PREPARATION METHOD FOR SMTP-7 DERIVATIVE AND INTERMEDIATE THEREOF 上海森辉医药有限公司 2025-02-13 — — WO disclosed
WO-2025031476-A1 PREPARATION METHOD FOR SMTP-7 DERIVATIVE AND INTERMEDIATE THEREOF 上海森辉医药有限公司 2025-02-13 — — WO disclosed
EP-4504201-A1 INHIBITORS OF CHYMASE FOR USE IN THE SELECTIVE RESOLUTION OF THROMBI IN THROMBOTIC OR THROMBOEMBOLIC DISORDERS Socpra Sciences Santé Et Humaines S.E.C. (CA) 2025-02-12 — — EP disclosed
CN-119278042-A Chymase inhibitors for selective dissolution of thrombi in thrombotic or thromboembolic disorders 索克普拉健康与人文科学公司 2025-01-07 — — CN disclosed
EP-4482863-A1 TREATMENT OF CARDIOVASCULAR DISEASES USING ANTI-HUMAN GPVI ANTIBODIES Acticor Biotech (FR) 2025-01-01 — — EP disclosed
US-20240424093-A1 DRUG REGIMEN FOR TREATMENT OF CEREBRAL ISCHEMIA Shimojani, LLC (US) 2024-12-26 — — US disclosed
US-12138244-B2 Drug and method of treating or preventing renal disease using drug SHOWA UNIVERSITY (JP) 2024-11-12 — — US disclosed
EP-4293028-A4 SMTP-7 DERIVATIVE AND USE THEREOF Shanghai Senhui Medicine Co., Ltd. (CN) 2024-10-30 — — EP disclosed
US-12115141-B2 Diagnosis of diabetes by detecting aggregated amylin in erythrocytes UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2024-10-15 — — US disclosed
US-12109265-B2 Drug regimen for treatment of cerebral ischemia Shimojani, LLC (US) 2024-10-08 — — US disclosed
EP-4436567-A1 METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS Astrocyte Pharmaceuticals, Inc. (US) 2024-10-02 — — EP disclosed
CN-118414152-A Methods of treating neurological and cardiovascular conditions 阿斯特罗赛特制药公司 2024-07-30 — — CN disclosed
US-20240238248-A1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING CEREBRAL INFARCTION CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) 2024-07-18 — — US disclosed
US-20240238252-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) 2024-07-18 — — US disclosed
US-20240238248-A1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING CEREBRAL INFARCTION CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) 2024-07-18 — — US disclosed
US-20240238252-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) 2024-07-18 — — US disclosed
US-20240238252-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) 2024-07-18 — — US disclosed
JP-2024525998-A — ジーシン ファーマシューティカルズ ホンコン リミテッド 2024-07-16 — — JP disclosed
JP-2024525239-A — ジーシン ファーマシューティカルズ ホンコン リミテッド 2024-07-11 — — JP disclosed
JP-2024525239-A — ジーシン ファーマシューティカルズ ホンコン リミテッド 2024-07-11 — — JP disclosed
CN-118084942-B Preparation method of methylated SMTP-7 深圳创元生物医药科技有限公司 2024-06-28 — — CN disclosed
CN-118084942-B Preparation method of methylated SMTP-7 深圳创元生物医药科技有限公司 2024-06-28 — — CN disclosed
CN-118084942-B Preparation method of methylated SMTP-7 深圳创元生物医药科技有限公司 2024-06-28 — — CN disclosed
US-20240189280-A1 DRUG FOR TREATING OR PREVENTING CEREBRAL HEMORRHAGE, AND METHOD FOR TREATING OR PREVENTING CEREBRAL HEMORRHAGE USING THE DRUG CORXEL PHARMACEUTICALS HONG KONG LIMITED (CN) 2024-06-13 — — US disclosed
US-20240190896-A1 SMTP-7 DERIVATIVE AND USE THEREOF JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) 2024-06-13 — — US disclosed
US-20240190896-A1 SMTP-7 DERIVATIVE AND USE THEREOF JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) 2024-06-13 — — US disclosed
US-20240190896-A1 SMTP-7 DERIVATIVE AND USE THEREOF JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) 2024-06-13 — — US disclosed
CN-118084942-A Preparation method of methylated SMTP-7 深圳创元生物医药科技有限公司 2024-05-28 — — CN disclosed
CN-118084942-A Preparation method of methylated SMTP-7 深圳创元生物医药科技有限公司 2024-05-28 — — CN disclosed
CN-118084942-A Preparation method of methylated SMTP-7 深圳创元生物医药科技有限公司 2024-05-28 — — CN disclosed
EP-4337193-A1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING CEREBRAL INFARCTION Biogen MA Inc. (US) 2024-03-20 — — EP disclosed
EP-4337193-A1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING CEREBRAL INFARCTION Biogen MA Inc. (US) 2024-03-20 — — EP disclosed
EP-4326258-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 Biogen MA Inc. (US) 2024-02-28 — — EP disclosed
EP-4326258-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 Biogen MA Inc. (US) 2024-02-28 — — EP disclosed
EP-4326258-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 Biogen MA Inc. (US) 2024-02-28 — — EP disclosed
CN-117586283-A Crystal form of SMTP-7 derivative 江苏恒瑞医药股份有限公司 2024-02-23 — — CN disclosed
CN-117586283-A Crystal form of SMTP-7 derivative 江苏恒瑞医药股份有限公司 2024-02-23 — — CN disclosed
CN-117586283-A Crystal form of SMTP-7 derivative 江苏恒瑞医药股份有限公司 2024-02-23 — — CN disclosed
CN-117295497-A Pharmaceutical composition for treating cerebral infarction 渤健马萨诸塞州股份有限公司 2023-12-26 — — CN disclosed
US-11850232-B2 Drug for treating or preventing cerebral hemorrhage, and method for treating or preventing cerebral hemorrhage using the drug BIOGEN MA INC. (US) 2023-12-26 — — US disclosed
CN-117295497-A Pharmaceutical composition for treating cerebral infarction 渤健马萨诸塞州股份有限公司 2023-12-26 — — CN disclosed
CN-117279634-A Pharmaceutical composition comprising compound SMTP-7 渤健马萨诸塞州股份有限公司 2023-12-22 — — CN disclosed
CN-117279634-A Pharmaceutical composition comprising compound SMTP-7 渤健马萨诸塞州股份有限公司 2023-12-22 — — CN disclosed
EP-4293028-A1 SMTP-7 DERIVATIVE AND USE THEREOF Shanghai Senhui Medicine Co., Ltd. (CN) 2023-12-20 — — EP disclosed
EP-4293028-A1 SMTP-7 DERIVATIVE AND USE THEREOF Shanghai Senhui Medicine Co., Ltd. (CN) 2023-12-20 — — EP disclosed
EP-4293028-A1 SMTP-7 DERIVATIVE AND USE THEREOF Shanghai Senhui Medicine Co., Ltd. (CN) 2023-12-20 — — EP disclosed
EP-4289430-A2 THROMBOLYTIC AGENT AND BEVACIZUMAB FOR TREATMENT OF CEREBRAL ISCHEMIA Shimojani LLC (US) 2023-12-13 — — EP disclosed
CN-111936134-B Pharmaceutical agent and method for treating or preventing kidney disease using the same 学校法人昭和大学 2023-12-08 — — CN disclosed
JP-7381035-B2 — 学校法人昭和大学 2023-11-15 — — JP disclosed
WO-2023213869-A1 PLASMIN-BINDING VHHS Rheinische Friedrich-Wilhelms-Universität Bonn (DE) 2023-11-09 — — WO disclosed
WO-2023194222-A1 INHIBITORS OF CHYMASE FOR USE IN THE SELECTIVE RESOLUTION OF THROMBI IN THROMBOTIC OR THROMBOEMBOLIC DISORDERS SOCPRA SCIENCES SANTÉ HUMAINES S.E.C. (CA) 2023-10-12 — — WO disclosed
EP-4252752-A1 DRUG FOR TREATMENT OR PREVENTION OF CEREBRAL HEMORRHAGE, AND METHOD FOR TREATMENT OR PREVENTION OF CEREBRAL HEMORRHAGE USING SAID DRUG Biogen MA Inc. (US) 2023-10-04 — — EP disclosed
CN-116761600-A Medicament for treating or preventing cerebral hemorrhage and method for treating or preventing cerebral hemorrhage using the same 渤健马萨诸塞州股份有限公司 2023-09-15 — — CN disclosed
CN-116669723-A SMTP-7 derivative and application thereof 上海森辉医药有限公司 2023-08-29 — — CN disclosed
CN-116669723-A SMTP-7 derivative and application thereof 上海森辉医药有限公司 2023-08-29 — — CN disclosed
CN-116669723-A SMTP-7 derivative and application thereof 上海森辉医药有限公司 2023-08-29 — — CN disclosed
WO-2023156683-A1 TREATMENT OF CARDIOVASCULAR DISEASES USING ANTI-HUMAN GPVI ANTIBODIES ACTICOR BIOTECH (FR) 2023-08-24 — — WO disclosed
EP-3565546-B1 THROMBOLYTIC AGENT AND BEVACIZUMAB FOR TREATMENT OF CEREBRAL ISCHEMIA SHIMOJANI LLC (US) 2023-08-09 — — EP disclosed
WO-2023091791-A1 METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS ASTROCYTE PHARMACEUTICALS, INC. (US) 2023-05-25 — — WO disclosed
US-RE49351-E1 Cytoprotective agent BIOGEN MA INC. (US) 2023-01-03 — — US disclosed
WO-2022240810-A1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING CEREBRAL INFARCTION BIOGEN MA INC. (US) 2022-11-17 — — WO disclosed
WO-2022240810-A1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING CEREBRAL INFARCTION BIOGEN MA INC. (US) 2022-11-17 — — WO disclosed
WO-2022226013-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 BIOGEN MA INC. (US) 2022-10-27 — — WO disclosed
WO-2022226013-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 BIOGEN MA INC. (US) 2022-10-27 — — WO disclosed
WO-2022226013-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 BIOGEN MA INC. (US) 2022-10-27 — — WO disclosed
US-11440920-B2 Chemical method of producing SMTP groups or SMTP-7 and intermediates used in the method SHOWA UNIVERSITY (JP) 2022-09-13 — — US disclosed
US-11440920-B2 Chemical method of producing SMTP groups or SMTP-7 and intermediates used in the method SHOWA UNIVERSITY (JP) 2022-09-13 — — US disclosed
WO-2022171151-A1 SMTP-7 DERIVATIVE AND USE THEREOF 上海森辉医药有限公司 2022-08-18 — — WO disclosed
WO-2022171151-A1 SMTP-7 DERIVATIVE AND USE THEREOF 上海森辉医药有限公司 2022-08-18 — — WO disclosed
WO-2022171151-A1 SMTP-7 DERIVATIVE AND USE THEREOF 上海森辉医药有限公司 2022-08-18 — — WO disclosed
US-20220218664-A1 DRUG AND METHOD FOR TREATING OR PREVENTING COMPLICATIONS FROM DIABETES, USING SAID DRUG SHOWA UNIVERSITY (JP) 2022-07-14 — — US disclosed
CN-114126711-A Medicament and method for treating or preventing diabetic complications using the same 学校法人昭和大学 2022-03-01 — — CN disclosed
CN-114126711-A Medicament and method for treating or preventing diabetic complications using the same 学校法人昭和大学 2022-03-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250099427-A1 Drug and Method of Treating or Preventing Renal Disease Using Drug REN, ATP6V1B1, SLC10A1 ALOX5 117/4885APP 2305/4885PTPN1 3029/4885
US-12138244-B2 Drug and method of treating or preventing renal disease using drug REN, ATP6V1B1, SLC10A1 ALOX5 117/4885APP 2305/4885PTPN1 3029/4885
US-20260144792-A1 INHIBITORS OF CHYMASE FOR USE IN THE SELECTIVE RESOLUTION OF THROMBI IN THROMBOTIC OR THROMBOEMBOLIC DISORDERS F2R, CMA1, FGB ALOX5 1730/4885APP 3738/4885PTPN1 1054/4885
US-12453718-B2 Drug for treating or preventing cerebral hemorrhage, and method for treating or preventing cerebral hemorrhage using the drug PROC, FABP7, SERPINC1 ALOX5 285/4885APP 592/4885PTPN1 4588/4885
US-20220218664-A1 DRUG AND METHOD FOR TREATING OR PREVENTING COMPLICATIONS FROM DIABETES, USING SAID DRUG SLC5A2, SLC5A1, IAPP ALOX5 71/4885APP 728/4885PTPN1 2665/4885
US-20250302837-A1 INHIBITORS OF CHYMASE FOR USE IN THE SELECTIVE RESOLUTION OF THROMBI IN THROMBOTIC OR THROMBOEMBOLIC DISORDERS CMA1, SERPINB1, TPSB2 ALOX5 748/4885APP 4210/4885PTPN1 2657/4885
US-20250177405-A1 METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS ADORA2A, ADORA3, ADORA1 ALOX5 585/4885APP 1611/4885PTPN1 3210/4885
US-20240238248-A1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING CEREBRAL INFARCTION PSD, SCN7A, MBOAT7 ALOX5 3129/4885APP 1162/4885PTPN1 1836/4885
US-20240189280-A1 DRUG FOR TREATING OR PREVENTING CEREBRAL HEMORRHAGE, AND METHOD FOR TREATING OR PREVENTING CEREBRAL HEMORRHAGE USING THE DRUG PROC, FABP7, SERPINC1 ALOX5 285/4885APP 592/4885PTPN1 4588/4885
US-11440920-B2 Chemical method of producing SMTP groups or SMTP-7 and intermediates used in the method SMS, TST, TES ALOX5 4649/4885APP 1966/4885PTPN1 3184/4885
US-20240238252-A1 PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND SMTP-7 SMPD1, SMPD3, MBOAT7 ALOX5 2914/4885APP 695/4885PTPN1 2494/4885
US-11850232-B2 Drug for treating or preventing cerebral hemorrhage, and method for treating or preventing cerebral hemorrhage using the drug PROC, FABP7, SERPINC1 ALOX5 285/4885APP 592/4885PTPN1 4588/4885
US-20240190896-A1 SMTP-7 DERIVATIVE AND USE THEREOF SMPD1, SMPD2, SMPD3 ALOX5 4154/4885APP 3481/4885PTPN1 1313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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