Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.46 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29860575 | 0.87 | PHLPP2 (0.55) | THRBMAPK1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL1743198 | 0.79 | THRB (0.67) | THRBMAPK1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL1435840 | 0.79 | THRB (0.67) | THRBMAPK1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL29625856 | 0.79 | THRB (0.67) | THRBMAPK1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL31511329 | 0.76 | THRB (0.56) | THRBMAPK1ALDH1A1TDP1HIF1A | |
| SCHEMBL14418376 | 0.75 | MAPK1 (0.65) | THRBMAPK1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL29527953 | 0.75 | ALDH1A1 (0.57) | THRBMAPK1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL29624560 | 0.74 | THRB (0.61) | THRBMAPK1ALDH1A1TDP1RECQL | |
| SCHEMBL136632 | 0.74 | THRB (0.64) | THRBMAPK1ALDH1A1TDP1RECQL | |
| SCHEMBL29423647 | 0.74 | THRB (0.64) | THRBMAPK1ALDH1A1TDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230194387-A1 | DEVICE FOR TESTING OF AN ENVIRONMENTAL SAMPLE | BECTON, DICKINSON AND COMPANY | 2023-06-22 | — | — | US | claimed |
| EP-4189359-A1 | DEVICE FOR TESTING OF AN ENVIRONMENTAL SAMPLE | Becton, Dickinson and Company (US) | 2023-06-07 | — | — | EP | claimed |
| WO-2022056084-A1 | DEVICE FOR TESTING OF AN ENVIRONMENTAL SAMPLE | BECTON, DICKINSON AND COMPANY (US) | 2022-03-17 | — | — | WO | claimed |
| EP-3965738-B1 | METHOD FOR PRODUCTION OF LIPOSOMES | UNIV DO MINHO (PT) | 2025-08-06 | — | — | EP | disclosed |
| US-20240301480-A1 | METHODS AND COMPOSITIONS FOR ANALYZING NUCLEIC ACIDS AND NUCLEASES IN A BODY FLUID AS INDICATORS OF DISEASE | ARNA GENOMICS US INCORPORATED | 2024-09-12 | — | — | US | disclosed |
| US-20240167934-A1 | EXCITATION-EMISSION MATRIX FLOW CYTOMETRY SYSTEMS AND USES THEREOF | SCINTILLON INSTITUTE FOR BIOMEDICAL AND BIOENERGY RESEARCH | 2024-05-23 | — | — | US | disclosed |
| EP-4291870-A1 | EXCITATION-EMISSION MATRIX FLOW CYTOMETRY SYSTEMS AND USES THEREOF | Scintillon Institute for Biomedical and Bioenergy Research (US) | 2023-12-20 | — | — | EP | disclosed |
| US-20230400412-A1 | FOLIC ACID FUNCTIONALIZED COPPER SULFIDE NANOPARTICLES FOR THE DETECTION OF OVARIAN CANCER CELLS IN FLOW | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2023-12-14 | — | — | US | disclosed |
| US-20230357868-A1 | COMPOSITIONS AND METHODS FOR OBTAINING PLANT CULTIVARS WITH DESIRED TERPENE PROFILES BASED ON TERPENE SYNTHASE GENE SELECTION | FRONT RANGE BIOSCIENCES INC (US) | 2023-11-09 | — | — | US | disclosed |
| US-11788965-B2 | Folic acid functionalized copper sulfide nanoparticles for the detection of ovarian cancer cells in flow | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230251194-A1 | OPTICAL ANALYSES OF PARTICLES AND VESICLES | SCINTILLON INSTITUTE FOR BIOMEDICAL AND BIOENERGY RESEARCH | 2023-08-10 | — | — | US | disclosed |
| US-20230194387-A1 | DEVICE FOR TESTING OF AN ENVIRONMENTAL SAMPLE | BECTON, DICKINSON AND COMPANY | 2023-06-22 | — | — | US | disclosed |
| EP-4189359-A1 | DEVICE FOR TESTING OF AN ENVIRONMENTAL SAMPLE | Becton, Dickinson and Company (US) | 2023-06-07 | — | — | EP | disclosed |
| WO-2023086970-A2 | METHODS AND COMPOSITIONS FOR ANALYZING NUCLEIC ACIDS AND NUCLEASES IN A BODY FLUID AS INDICATORS OF DISEASE | ARNA GENOMICS US INCORPORATED (US) | 2023-05-19 | — | — | WO | disclosed |
| US-11486829-B2 | Optical analyses of particles and vesicles | SCINTILLON INSTITUTE FOR BIOMEDICAL AND BIOENERGY RESEARCH (US) | 2022-11-01 | — | — | US | disclosed |
| WO-2022174056-A1 | EXCITATION-EMISSION MATRIX FLOW CYTOMETRY SYSTEMS AND USES THEREOF | SCINTILLON INSTITUTE FOR BIOMEDICAL AND BIOENERGY RESEARCH (US) | 2022-08-18 | — | — | WO | disclosed |
| US-20220241203-A1 | METHOD FOR PRODUCTION OF LIPOSOMES | UNIVERSIDADE DO MINHO (PT) | 2022-08-04 | — | — | US | disclosed |
| WO-2022056084-A1 | DEVICE FOR TESTING OF AN ENVIRONMENTAL SAMPLE | BECTON, DICKINSON AND COMPANY (US) | 2022-03-17 | — | — | WO | disclosed |