Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CD40 | P25942 | 1/20 | 0.40 |
| ▸ | CD40LG | P29965 | 1/20 | 0.40 |
| ▸ | ATIC | P31939 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069683 | 0.87 | THRB (0.49) | THRBALDH1A1HIF1ACYP3A4ALOX15 | |
| SCHEMBL16566668 | 0.79 | THRB (0.55) | THRBALDH1A1HIF1ACYP3A4ALOX15 | |
| SCHEMBL29540025 | 0.79 | THRB (0.55) | THRBALDH1A1HIF1ACYP3A4ALOX15 | |
| SCHEMBL29625849 | 0.79 | THRB (0.57) | THRBHIF1AMAPK1RECQLHSD17B10 | |
| SCHEMBL29399244 | 0.75 | ALDH1A1 (0.65) | THRBALDH1A1HIF1ACYP3A4ALOX15 | |
| SCHEMBL13875770 | 0.75 | ALDH1A1 (0.47) | THRBALDH1A1HIF1ACYP3A4ALOX15 | |
| SCHEMBL29568770 | 0.73 | THRB (0.86) | THRBALDH1A1HIF1ACYP3A4ALOX15 | |
| SCHEMBL30255031 | 0.71 | PRMT1 (0.67) | THRBPRMT1CARM1ENPP2CD40 | |
| SCHEMBL29438052 | 0.70 | THRB (0.52) | THRBALDH1A1HIF1ACYP3A4ALOX15 | |
| SCHEMBL29527953 | 0.69 | ALDH1A1 (0.57) | THRBALDH1A1HIF1ACYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547208-B1 | PROCESS FOR REMOVING THE COLOUR FROM PREVIOUSLY DYED KERATINOUS HAIR FIBRES | OREAL (FR) | 2026-05-27 | — | — | EP | disclosed |
| US-12636246-B2 | Process for colouring hair keratin fibers, comprising the application of a composition comprising at least one (poly)carbodiimide compound and a composition comprising at least one associative polymer and a particular compound | L'OREAL (FR) | 2026-05-26 | — | — | US | disclosed |
| EP-4703438-A1 | ULTRAVIOLET-CURABLE COMPOSITION, METHOD FOR PRODUCING CURED PRODUCT, CURED PRODUCT, ULTRAVIOLET-CURABLE INK, METHOD FOR PRODUCING PRINTED MATTER, AND PRINTED MATTER | Mitsubishi Chemical Corporation (JP) | 2026-03-04 | — | — | EP | disclosed |
| EP-4703437-A1 | ULTRAVIOLET-CURABLE COMPOSITION, METHOD FOR PRODUCING CURED PRODUCT, CURED PRODUCT, ULTRAVIOLET-CURABLE INK, METHOD FOR PRODUCING PRINTED MATTER, AND PRINTED MATTER | Mitsubishi Chemical Corporation (JP) | 2026-03-04 | — | — | EP | disclosed |
| WO-2026039882-A1 | METHODS FOR REDUCING COLOR FADING IN COLOR-TREATED HAIR | L'OREAL (FR) | 2026-02-26 | — | — | WO | disclosed |
| US-20260027027-A1 | FRAGRANCED COMPOSITION COMPRISING AT LEAST ONE SULFUR-COMPRISING ANTIOXIDANT COMPOUND, AT LEAST ONE ORGANIC UV SCREENING AGENT AND AT LEAST ONE FRAGRANCING SUBSTANCE | OREAL (FR) | 2026-01-29 | — | — | US | disclosed |
| US-12533303-B2 | Composition for the simultaneous bleaching and dyeing of keratin fibres and process using this composition | L'OREAL (FR) | 2026-01-27 | — | — | US | disclosed |
| US-20260007583-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2026-01-08 | — | — | US | disclosed |
| US-20250381106-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2025-12-18 | — | — | US | disclosed |
| US-20250381107-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2025-12-18 | — | — | US | disclosed |
| CN-111344367-B | Block copolymer | 毕克化学有限公司 | 2022-06-17 | — | — | CN | disclosed |
| US-20220183944-A1 | PROCESS FOR DYEING KERATIN MATERIALS USING A DIRECT DYE AND AN ALIPHATIC AMMONIUM SALT, AND COMPOSITION COMPRISING SAME | L'OREAL (FR) | 2022-06-16 | — | — | US | disclosed |
| CN-111094474-B | Near-infrared-curable ink composition, near-infrared-curable film, method for producing near-infrared-curable film, and method for photo-molding | 住友金属矿山株式会社 | 2022-06-07 | — | — | CN | disclosed |
| CN-114574036-A | Ink, method for manufacturing ink, and inkjet system | 株式会社理光 | 2022-06-03 | — | — | CN | disclosed |
| US-20220169877-A1 | INK, METHOD FOR PRODUCING INK, AND INKJET SYSTEM | RICOH COMPANY, LTD. (JP) | 2022-06-02 | — | — | US | disclosed |
| CN-114460809-A | Negative photosensitive resin composition, cured film, display device provided with cured film, and method for producing same | 东丽株式会社 | 2022-05-10 | — | — | CN | disclosed |
| EP-3986366-A1 | COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE, AT LEAST ONE NON-AMINO SILICONE AND WATER, THE ALKOXYSILANE/NON-AMINO SILICONE MASS RATIO RANGING FROM 95/5 TO 5/95 | L'OREAL (FR) | 2022-04-27 | — | — | EP | disclosed |
| US-20220121113-A1 | OXIME ESTER PHOTOINITIATORS HAVING A SPECIAL AROYL CHROMOPHORE | BASF SE (DE) | 2022-04-21 | — | — | US | disclosed |
| CN-114340588-A | Composition comprising at least one alkoxysilane of formula (I), at least one alkoxysilane of formula (II), at least one non-amino silicone and optionally a pigment and/or direct dye | 莱雅公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-108885399-B | Negative photosensitive resin composition, cured film, display device provided with cured film, and method for producing same | 东丽株式会社 | 2022-03-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12533303-B2 | Composition for the simultaneous bleaching and dyeing of keratin fibres and process using this composition | KRT18, CA12, CA7 | THRB 2468/4885ALDH1A1 1626/4885HIF1A 2516/4885 |
| US-20260027027-A1 | FRAGRANCED COMPOSITION COMPRISING AT LEAST ONE SULFUR-COMPRISING ANTIOXIDANT COMPOUND, AT LEAST ONE ORGANIC UV SCREENING AGENT AND AT LEAST ONE FRAGRANCING SUBSTANCE | CBR3, CBR1, ERCC1 | THRB 3716/4885ALDH1A1 52/4885HIF1A 1945/4885 |
| US-20250381106-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | KRT18, VIM, MAP1LC3A | THRB 4386/4885ALDH1A1 730/4885HIF1A 3112/4885 |
| US-20260007583-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | KRT18, F12, VIM | THRB 3644/4885ALDH1A1 1427/4885HIF1A 3174/4885 |
| US-12636246-B2 | Process for colouring hair keratin fibers, comprising the application of a composition comprising at least one (poly)carbodiimide compound and a composition comprising at least one associative polymer and a particular compound | KRT18, CYC1, CYBA | THRB 1477/4885ALDH1A1 197/4885HIF1A 1915/4885 |
| US-20220183944-A1 | PROCESS FOR DYEING KERATIN MATERIALS USING A DIRECT DYE AND AN ALIPHATIC AMMONIUM SALT, AND COMPOSITION COMPRISING SAME | KRT18, MARK1, IK | THRB 4055/4885ALDH1A1 873/4885HIF1A 3623/4885 |
| US-20250381107-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | KRT18, VIM, MAP1LC3A | THRB 4273/4885ALDH1A1 739/4885HIF1A 3160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.