Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.57 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTPRA | P18433 | 1/20 | 0.46 |
| ▸ | PTPRB | P23467 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394555 | 0.80 | GLO1 (0.68) | THRBGLO1PTPN1MAPTKMT2A | |
| SCHEMBL29421893 | 0.80 | GLO1 (0.64) | THRBGLO1MAPTKMT2AMEN1 | |
| SCHEMBL29420733 | 0.79 | THRB (0.55) | THRBPTPN1KMT2AMEN1TDP1 | |
| SCHEMBL10723393 | 0.78 | GLO1 (0.79) | THRBGLO1PTPN1MAPTKMT2A | |
| SCHEMBL23787549 | 0.77 | SENP2 (0.59) | GLO1MAPTKMT2AGAATDP1 | |
| SCHEMBL144504 | 0.76 | MAPT (0.78) | THRBGLO1MAPTKMT2AMEN1 | |
| SCHEMBL339399 | 0.76 | MAPT (0.78) | THRBGLO1MAPTKMT2AMEN1 | |
| SCHEMBL29378285 | 0.76 | MAPT (0.78) | THRBGLO1MAPTKMT2AMEN1 | |
| SCHEMBL29353711 | 0.76 | MAPT (0.78) | THRBGLO1MAPTKMT2AMEN1 | |
| SCHEMBL29624560 | 0.76 | THRB (0.61) | THRBGLO1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051975-A1 | SYSTEMS AND METHODS FOR PRODUCING A BUNDLE OF FILAMENTS AND/OR A YARN | ALADDIN MANUFACTURING CORPORATION | 2025-02-13 | — | — | US | disclosed |
| US-20250051968-A1 | SYSTEMS AND METHODS FOR PRODUCING A BUNDLE OF FILAMENTS AND/OR A YARN | ALADDIN MANUFACTURING CORPORATION | 2025-02-13 | — | — | US | disclosed |
| US-20250011973-A1 | SYSTEMS & METHODS FOR PRODUCING A BUNDLE OF A COMBINATION OF FILAMENTS AND/OR A YARN | ALADDIN MANUFACTURING CORPORATION | 2025-01-09 | — | — | US | disclosed |
| CN-118414456-A | System and method for producing filament bundles and/or yarns | 美国阿拉丁制造公司 | 2024-07-30 | — | — | CN | disclosed |
| US-20240052540-A1 | MULTICOLORED TUFTED TEXTILES AND METHODS OF MAKING THE SAME | ALADDIN MANUFACTURING CORPORATION | 2024-02-15 | — | — | US | disclosed |
| US-20230414826-A1 | FIBRIN HYDROGELS | RESEARCH, MAYO FOUNDATION FOR MEDICAL EDUCATION AND (US) | 2023-12-28 | — | — | US | disclosed |
| EP-4263927-A1 | MULTICOLORED TUFTED TEXTILES AND METHODS OF MAKING THE SAME | Aladdin Manufacturing Corporation (US) | 2023-10-25 | — | — | EP | disclosed |
| EP-4243850-A1 | FIBRIN HYDROGELS | Mayo Foundation for Medical Education and Research (US) | 2023-09-20 | — | — | EP | disclosed |
| CN-116669754-A | Fibrin hydrogel | 梅约医学教育与研究基金会 | 2023-08-29 | — | — | CN | disclosed |
| CN-116669597-A | Multicolor tufted textile and method of making the same | 美国阿拉丁制造公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2023111759-A1 | SYSTEMS AND METHODS FOR PRODUCING A BUNDLE OF FILAMENTS AND/OR A YARN | ALADDIN MANUFACTURING CORPORATION (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023111758-A1 | SYSTEMS AND METHODS FOR PRODUCING A BUNDLE OF FILAMENTS AND/OR A YARN | ALADDIN MANUFACTURING CORPORATION (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2022104128-A9 | FIBRIN HYDROGELS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2023-03-30 | — | — | WO | disclosed |
| WO-2022132965-A1 | MULTICOLORED TUFTED TEXTILES AND METHODS OF MAKING THE SAME | ALADDIN MANUFACTURING CORPORATION (US) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022104128-A1 | FIBRIN HYDROGELS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2022-05-19 | — | — | WO | disclosed |