Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GRK2 | P25098 | 1/20 | 0.55 |
| ▸ | PLEC | Q15149 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PTPRA | P18433 | 1/20 | 0.52 |
| ▸ | PTPRB | P23467 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31525848 | 0.86 | CYP1A2 (0.67) | KMT2AMEN1CYP1A2CYP2C9HIF1A | |
| SCHEMBL14418371 | 0.86 | CYP1A2 (0.67) | KMT2AMEN1CYP1A2CYP2C9HIF1A | |
| SCHEMBL11763437 | 0.86 | CYP1A2 (0.67) | KMT2AMEN1CYP1A2CYP2C9HIF1A | |
| SCHEMBL9577791 | 0.85 | THRB (0.60) | KMT2AMEN1CYP1A2CYP2C9HIF1A | |
| SCHEMBL29357249 | 0.85 | THRB (0.60) | KMT2AMEN1CYP1A2CYP2C9HIF1A | |
| SCHEMBL9577785 | 0.85 | THRB (0.60) | KMT2AMEN1CYP1A2CYP2C9HIF1A | |
| SCHEMBL29366329 | 0.84 | THRB (0.65) | KMT2AMEN1CYP1A2CYP2C9HIF1A | |
| Pontacyl Violet 6R SCHEMBL29862139 | 0.82 | CYP1A2 (0.74) | KMT2AMEN1POLBGRK2PLEC | |
| SCHEMBL93701 | 0.82 | APP (0.72) | KMT2AMEN1POLBGRK2PLEC | |
| SCHEMBL29353967 | 0.82 | APP (0.72) | KMT2AMEN1POLBGRK2PLEC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025099313-A1 | REDUCING BACKGROUND FLUORESCENCE IN SINGLE MOLECULE FLUORESCENCE IN SITU HYBRIDIZATION APPLICATIONS | RESOLVE BIOSCIENCES GMBH (DE) | 2025-05-15 | — | — | WO | disclosed |
| CN-111213056-B | Colorimetric aerosol and gas detection for aerosol delivery devices | 莱战略控股公司 | 2022-10-04 | — | — | CN | disclosed |
| US-11236234-B2 | Joint compounds and plasters with a complexometric dye and methods | UNITED STATES GYPSUM COMPANY (US) | 2022-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11236234-B2 | Joint compounds and plasters with a complexometric dye and methods | LCP1, INTS6, PLOD2 | THRB 4881/4885KMT2A 451/4885MEN1 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.