SCHEMBL29439944

SCHEMBL29439944

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1OP(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RNASEL Q05823 9/20 0.84
▸ ADORA1 P30542 2/20 0.82
▸ DNPH1 O43598 1/20 0.81
▸ PRKAB2 O43741 1/20 0.81
▸ TRPM2 O94759 1/20 0.81
▸ LDHA P00338 1/20 0.81
▸ ADRB2 P07550 1/20 0.81
▸ FBP1 P09467 1/20 0.81
▸ SRC P12931 1/20 0.81
▸ P2RY2 P41231 1/20 0.81
▸ P2RY1 P47900 1/20 0.81
▸ PRKAG1 P54619 1/20 0.81
▸ PRKAA2 P54646 1/20 0.81
▸ PDE4D Q08499 1/20 0.81
▸ KCNH2 Q12809 1/20 0.81
▸ PRKAA1 Q13131 1/20 0.81
▸ PDE3A Q14432 1/20 0.81
▸ SMN1; SMN2 Q16637 1/20 0.81
▸ TAS1R3 Q7RTX0 1/20 0.81
▸ TAS1R1 Q7RTX1 1/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30203821 1.00 RNASEL (0.84) RNASELADORA1DNPH1PRKAB2TRPM2
SCHEMBL1122523 1.00 RNASEL (0.84) RNASELADORA1DNPH1PRKAB2TRPM2
SCHEMBL21068029 1.00 RNASEL (0.84) RNASELADORA1DNPH1PRKAB2TRPM2
SCHEMBL31266503 0.93 P2RY1 (0.83) RNASELADORA1DNPH1PRKAB2TRPM2
SCHEMBL21067751 0.93 P2RY1 (0.83) RNASELADORA1DNPH1PRKAB2TRPM2
SCHEMBL23867092 0.93 P2RY1 (0.83) RNASELADORA1DNPH1PRKAB2TRPM2
SCHEMBL1061029 0.93 P2RY1 (0.83) RNASELADORA1DNPH1PRKAB2TRPM2
SCHEMBL15498428 0.93 P2RY1 (0.83) RNASELADORA1DNPH1PRKAB2TRPM2
SCHEMBL29431883 0.93 P2RY1 (0.83) RNASELADORA1DNPH1PRKAB2TRPM2
SCHEMBL42104 0.93 P2RY1 (0.83) RNASELADORA1DNPH1PRKAB2TRPM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11353448-B2 Methods and compositions for quantifying metabolites and proteins from single cells CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2022-06-07 — — US claimed
US-20260034071-A1 HIGH-PURITY PEG LIPIDS AND USES THEREOF MODERNATX, INC. (US) 2026-02-05 — — US disclosed
US-12466874-B2 Prevention of protein disulfide bond reduction MEDIMMUNE LLC (US) 2025-11-11 — — US disclosed
US-20250320190-A1 Novel Inhibitors of Leucine Carboxyl Methyltransferase-1 (LCMT-1) and Methods of Use Thereof UNIV TEMPLE (US) 2025-10-16 — — US disclosed
US-12383508-B2 High-purity peg lipids and uses thereof MODERNATX, INC. (US) 2025-08-12 — — US disclosed
CN-120060182-A Nucleic acid modified protein and application thereof 深圳市儿童医院 2025-05-30 — — CN disclosed
US-20250152518-A1 PEG LIPIDS AND USES THEREOF MODERNATX, INC. (US) 2025-05-15 — — US disclosed
EP-4509118-A2 HIGH-PURITY PEG LIPIDS AND USES THEREOF ModernaTX, Inc. (US) 2025-02-19 — — EP disclosed
CN-119355251-A Identification mark for accurately distinguishing drinking death from post-death wine filling and identification method thereof 山西医科大学 2025-01-24 — — CN disclosed
US-12151029-B2 PEG lipids and uses thereof MODERNATX, INC. (US) 2024-11-26 — — US disclosed
CN-115605603-A Method for producing sulfated polysaccharide and method for producing PAPS 伦斯莱尔工艺研究院(US) 2023-01-13 — — CN disclosed
US-20220265857-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS MODERNATX, INC. (US) 2022-08-25 — — US disclosed
CN-113151316-B Method for improving heat resistance of plants by controlling content of MECPP (mecPP) through controlling HDS22 gene 湖北大学 2022-06-24 — — CN disclosed
CN-114616340-A Process for the synthesis of anticoagulant polysaccharides 奥普蒂姆维亚有限公司 2022-06-10 — — CN disclosed
WO-2022119914-A1 METHODS OF INHIBITING RNA PROOFREADING AND THERAPEUTIC APPLICATIONS THEREOF SCHMIER BRAD (US) 2022-06-09 — — WO disclosed
US-11353448-B2 Methods and compositions for quantifying metabolites and proteins from single cells CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2022-06-07 — — US disclosed
US-20220098282-A1 PREVENTION OF PROTEIN DISULFIDE BOND REDUCTION MEDIMMUNE LLC 2022-03-31 — — US disclosed
EP-3386484-B1 COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2022-03-30 — — EP disclosed
US-11285222-B2 Compositions and methods for delivery of agents MODERNATX, INC. (US) 2022-03-29 — — US disclosed
US-20220031631-A1 HIGH-PURITY PEG LIPIDS AND USES THEREOF MODERNATX, INC. (US) 2022-02-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250152518-A1 PEG LIPIDS AND USES THEREOF LIPA, LIPG, LIPC RNASEL 1352/4885ADORA1 4705/4885DNPH1 1795/4885
US-20220031631-A1 HIGH-PURITY PEG LIPIDS AND USES THEREOF LIPA, HDLBP, PLTP RNASEL 1117/4885ADORA1 4639/4885DNPH1 2573/4885
US-11285222-B2 Compositions and methods for delivery of agents HDLBP, APOB, TSG101 RNASEL 478/4885ADORA1 2677/4885DNPH1 4676/4885
US-20260034071-A1 HIGH-PURITY PEG LIPIDS AND USES THEREOF LNPEP, AUP1, PLTP RNASEL 2073/4885ADORA1 2269/4885DNPH1 2887/4885
US-20220265857-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS HDLBP, APOB, TSG101 RNASEL 478/4885ADORA1 2677/4885DNPH1 4676/4885
US-12151029-B2 PEG lipids and uses thereof LIPA, LIPG, LNPEP RNASEL 1205/4885ADORA1 4735/4885DNPH1 1887/4885
US-12383508-B2 High-purity peg lipids and uses thereof LIPA, HDLBP, PLTP RNASEL 1117/4885ADORA1 4639/4885DNPH1 2573/4885
US-20250320190-A1 Novel Inhibitors of Leucine Carboxyl Methyltransferase-1 (LCMT-1) and Methods of Use Thereof GNMT, BHMT, SHMT1 RNASEL 3543/4885ADORA1 3630/4885DNPH1 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback