SCHEMBL294471

SCHEMBL294471

CC(C)=CC1C(C(=O)OC2CC(C)CCC2C(C)C)C1(C)C

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.45
LMNA P02545 2/20 0.44
ALDH1A1 P00352 7/20 0.42
HPGD P15428 2/20 0.42
CYP19A1 P11511 2/20 0.41
TSHR P16473 3/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
MAPK1 P28482 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
TRPA1 O75762 2/20 0.38
TRPM8 Q7Z2W7 2/20 0.38
USP2 O75604 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL295262 0.91 EPHX1 (0.46) EPHX1LMNAALDH1A1HPGDCYP19A1
SCHEMBL4888060 0.91 EPHX1 (0.44) EPHX1LMNAALDH1A1HPGDCYP19A1
SCHEMBL4888048 0.91 EPHX1 (0.44) EPHX1LMNAALDH1A1HPGDCYP19A1
SCHEMBL1073398 0.90 EPHX1 (0.43) EPHX1LMNAALDH1A1HPGDCYP19A1
SCHEMBL1073394 0.90 EPHX1 (0.43) EPHX1LMNAALDH1A1HPGDCYP19A1
SCHEMBL2128363 0.89 EPHX1 (0.51) EPHX1LMNAALDH1A1HPGDCYP19A1
SCHEMBL1072050 0.89 EPHX1 (0.42) EPHX1LMNAALDH1A1HPGDCYP19A1
SCHEMBL294434 0.89 EPHX1 (0.45) EPHX1LMNAALDH1A1HPGDCYP19A1
SCHEMBL1072054 0.89 EPHX1 (0.42) EPHX1LMNAALDH1A1HPGDCYP19A1
SCHEMBL294435 0.89 EPHX1 (0.45) EPHX1LMNAALDH1A1HPGDCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1683783-B1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2012-03-14 EP disclosed
EP-1683782-B1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2012-03-14 EP disclosed
EP-1797953-B1 PROCESS FOR PRODUCING OXYGENIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2011-01-05 EP disclosed
US-20100204038-A1 Catalysts based on metal complexes for the synthesis of optically active chrysanthemic acid CARLONI SILVIA 2010-08-12 US disclosed
US-7723539-B2 Catalysts based on metal complexes for the synthesis of optically active chrysanthemic acid ENDURA S.P.A. (IT) 2010-05-25 US disclosed
EP-1120402-B1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2008-06-25 EP disclosed
US-20080064898-A1 Method for Producing Oxygen-Containing Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-03-13 US disclosed
US-20080021237-A1 Catalysts Based on Metal Complexes for the Synthesis of Optically Active Chrysanthemic Acid ENDURA S.P.A. (IT) 2008-01-24 US disclosed
US-7276622-B2 Method for producing oxygen-containing compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-02 US disclosed
EP-1797953-A1 PROCESS FOR PRODUCING OXYGENIC COMPOUND Sumitomo Chemical Company, Limited (JP) 2007-06-20 EP disclosed
WO-2003066559-A1 PROCESS FOR PRODUCTION OF ALDEHYDES AND KETONES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-08-14 WO disclosed
US-6489505-B2 REACTING CHRYSANTHEMIC ACID ESTER WITH HYDROGEN PEROXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-03 US disclosed
US-6469198-B2 OBTAINED BY CONTACTING N-SALICYLIDENEAMINOALCOHOL WITH MONO OR DIVALENT COPPER COMPOUND; FORMATION OF OPTICALLY ACTIVE CYCLOPROPANE-CARBOXYLIC ESTER FROM PROCHIRAL OLEFIN AND DIAZOACETIC ACID ESTER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-10-22 US disclosed
EP-1188735-A1 Process for producing carbonyl or hydroxy compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-20 EP disclosed
US-20020010361-A1 Process for producing 3,3-dimethyl-2- formylcyclopropane-carboxylic acid ester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-24 US disclosed
US-20020004618-A1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-10 US disclosed
US-20010037036-A1 Chiral copper complex catalyst composition and asymmetric production process using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-11-01 US disclosed
EP-1120402-A2 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-01 EP disclosed
EP-1120393-A1 A process for producing 3,3-dimethyl-2-formylcyclopropane-carboxylic acid ester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-01 EP disclosed
EP-1120401-A2 Chiral copper complex catalyst composition and asymmetric production process using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080064898-A1 Method for Producing Oxygen-Containing Compound AOC2, AOX1, CAT EPHX1 321/4885LMNA 3622/4885ALDH1A1 36/4885
US-20020010361-A1 Process for producing 3,3-dimethyl-2- formylcyclopropane-carboxylic acid ester ACSL6, ACSL3, TRMT1L EPHX1 3257/4885LMNA 4764/4885ALDH1A1 3786/4885
US-20010037036-A1 Chiral copper complex catalyst composition and asymmetric production process using the same AP1M1, UBA3, AP1S1 EPHX1 1268/4885LMNA 4316/4885ALDH1A1 254/4885
US-20080021237-A1 Catalysts Based on Metal Complexes for the Synthesis of Optically Active Chrysanthemic Acid SCO2, ME1, ME3 EPHX1 4122/4885LMNA 2779/4885ALDH1A1 1925/4885
US-20020004618-A1 Chiral copper complex and production processes thereof and using the same SOD1, XDH, NFXL1 EPHX1 1392/4885LMNA 4559/4885ALDH1A1 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.