SCHEMBL29448181

SCHEMBL29448181

O=C([O-])c1ccc(Cl)c(Cl)c1.[Na+]

nearest known ligand 0.61

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 known ✓ P00915 7/20 0.58
CA2 known ✓ P00918 7/20 0.58
TSHR P16473 1/20 0.61
SRD5A2 P31213 1/20 0.53
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
MAPT P10636 1/20 0.50
PKM P14618 1/20 0.50
RAB9A P51151 1/20 0.50
KMT2A Q03164 1/20 0.50
HPGD P15428 2/20 0.48
POLB P06746 1/20 0.47
HTT P42858 1/20 0.47
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
FLT1 P17948 1/20 0.46
FLT4 P35916 1/20 0.46
KDR P35968 1/20 0.46
KMO O15229 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4847002 1.00 TSHR (0.61) TSHRCA1CA2SRD5A2KDM4E
Zinc Ion SCHEMBL10603900 0.95 TSHR (0.61) TSHRCA1CA2SRD5A2KDM4E
Potassium Ion SCHEMBL9225991 0.95 TSHR (0.61) TSHRCA1CA2SRD5A2KDM4E
SCHEMBL31384757 0.83 CA2 (0.54) TSHRCA1CA2SRD5A2KDM4E
Zinc Ion SCHEMBL29096678 0.78 CA1 (0.50) TSHRCA1CA2SRD5A2KDM4E
SCHEMBL3184435 0.78 TSHR (0.70) TSHRSRD5A2KDM4EMEN1NPC1
SCHEMBL6322177 0.78 SRD5A2 (0.79) TSHRSRD5A2KDM4EMEN1NPC1
Potassium Ion SCHEMBL5794413 0.77 ALDH1A1 (0.51) TSHRCA1CA2HPGDPOLB
4-Chloro-3-Nitrobenzoic Acid SCHEMBL10608942 0.77 VCAM1 (0.74) CA1CA2KDM4EMEN1MAPT
SCHEMBL8007954 0.77 CA2 (0.47) TSHRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118452207-A Additive composition for pigment disinfection and method thereof 金诺斯公司 2024-08-09 CN disclosed
CN-116941998-A Apparatus, composition and method for decontaminating surfaces 金诺斯公司 2023-10-27 CN disclosed
CN-112512318-B Apparatus, composition and method for decontaminating surfaces 金诺斯公司 2023-07-04 CN disclosed
CN-114258912-A Compositions and methods for surface decontamination 金诺斯公司 2022-04-01 CN disclosed