Salcaprozic Acid

Salcaprozic Acid

SCHEMBL29509907

O=C([O-])CCCCCCCNC(=O)c1ccccc1O.[Na+]

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Salcaprozic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 known ✓ P09917 3/20 0.60
▸ NAAA Q02083 2/20 0.67
▸ HTT P42858 3/20 0.58
▸ ALDH1A1 P00352 3/20 0.58
▸ TSHR P16473 2/20 0.58
▸ HPGD P15428 2/20 0.58
▸ NPC1 O15118 1/20 0.58
▸ MAPT P10636 1/20 0.58
▸ NPSR1 Q6W5P4 1/20 0.58
▸ HSD17B10 Q99714 1/20 0.58
▸ NLRP1 Q9C000 1/20 0.58
▸ NAMPT P43490 1/20 0.56
▸ HDAC7 Q8WUI4 1/20 0.51
▸ KDM4E B2RXH2 2/20 0.50
▸ MEN1 O00255 1/20 0.46
▸ POLB P06746 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ ESRRG P62508 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salcaprozic Acid SCHEMBL825599 1.00 NAAA (0.67) NAAAALOX5HTTALDH1A1TSHR
SCHEMBL253212 1.00 NAAA (0.67) NAAAALOX5HTTALDH1A1TSHR
Salcaprozic Acid SCHEMBL20511604 1.00 NAAA (0.67) NAAAALOX5HTTALDH1A1TSHR
SCHEMBL2331877 1.00 NAAA (0.67) NAAAALOX5HTTALDH1A1TSHR
Salcaprozic Acid SCHEMBL26908047 0.97 NAAA (0.67) NAAAALOX5HTTALDH1A1TSHR
Alcohol SCHEMBL2331970 0.95 NAAA (0.68) NAAAALOX5HTTALDH1A1TSHR
SCHEMBL4956771 0.94 TSHR (0.61) NAAAALOX5HTTALDH1A1TSHR
Salcaprozic Acid SCHEMBL29036081 0.90 NAAA (0.65) NAAAALOX5HTTALDH1A1TSHR
Salcaprozic Acid SCHEMBL29036010 0.90 NAAA (0.65) NAAAALOX5HTTALDH1A1TSHR
SCHEMBL823552 0.87 NAAA (0.84) NAAAALOX5HTTALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025119007-A1 GROUP OF ANTISENSE OLIGONUCLEOTIDES THAT SPECIFICALLY INHIBIT ANDROGEN RECEPTOR, AND USE THEREOF 成都凌泰氪生物技术有限公司 2025-06-12 — — WO claimed
US-20250367295-A1 FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS SPOKE SCIENCES, INC. (US) 2025-12-04 — — US disclosed
EP-3928776-B1 FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS SPOKE SCIENCES INC (US) 2025-11-12 — — EP disclosed
US-20250268861-A1 N-ACYLATED FATTY AMINO ACIDS TO REDUCE ABSORPTION VARIABILITY IN CANNABINOID BASED COMPOSITIONS SPOKE SCIENCES, INC. (US) 2025-08-28 — — US disclosed
WO-2025119007-A1 GROUP OF ANTISENSE OLIGONUCLEOTIDES THAT SPECIFICALLY INHIBIT ANDROGEN RECEPTOR, AND USE THEREOF 成都凌泰氪生物技术有限公司 2025-06-12 — — WO disclosed
US-12303487-B2 N-acylated fatty amino acids to reduce absorption variability in cannabinoid based compositions SPOKE SCIENCES, INC. (US) 2025-05-20 — — US disclosed
US-20250120939-A1 FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS SPOKE SCIENCES, INC. (US) 2025-04-17 — — US disclosed
CN-118141941-B Abiraterone acetate-containing pharmaceutical composition and preparation method thereof 深圳市宇健生物医药有限公司 2024-12-20 — — CN disclosed
CN-118477051-A Fulvestrant tablet and preparation method thereof 南京安杰新生物医药有限公司 2024-08-13 — — CN disclosed
US-20240261408-A1 FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS SPOKE SCIENCES, INC. (US) 2024-08-08 — — US disclosed
EP-4054520-A1 SOLID COMPOSITIONS COMPRISING A PCSK9 INHIBITOR AND A SALT OF N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID Novo Nordisk A/S (DK) 2022-09-14 — — EP disclosed
WO-2022125913-A1 ORAL DELIVERY OF ANTISENSE CONJUGATES TARGETING PCSK9 CIVI BIOPHARMA, INC. (US) 2022-06-16 — — WO disclosed
EP-4009957-A1 SOLID COMPOSITION COMPRISING A PYY COMPOUND AND A SALT OF N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID Novo Nordisk A/S (DK) 2022-06-15 — — EP disclosed
EP-4009941-A1 SOLID COMPOSITIONS COMPRISING A GLP-1 AGONIST, AN SGLT2 INHIBITOR AND A SALT OF N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID Novo Nordisk A/S (DK) 2022-06-15 — — EP disclosed
EP-4009958-A1 SOLID COMPOSITIONS COMPRISING AN EGF(A) DERIVATIVE AND A SALT OF N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID Novo Nordisk A/S (DK) 2022-06-15 — — EP disclosed
WO-2022100737-A1 PHARMACEUTICAL COMPOSITION FOR NASAL ADMINISTRATION OF GLYBURIDE AND PREPARATION METHOD THEREFOR 江苏先声药业有限公司 2022-05-19 — — WO disclosed
WO-2022100736-A1 PHARMACEUTICAL COMPOSITION OF GLYBURIDE ADMINISTERED NASALLY 江苏先声药业有限公司 2022-05-19 — — WO disclosed
US-20220133685-A1 FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS RECEPTOR HOLDINGS, INC. (US) 2022-05-05 — — US disclosed
WO-2022072864-A2 STABILIZATION OF CANNABINOIDS WITHIN SOLID DOSAGE FORMS RECEPTOR HOLDINGS, INC. (US) 2022-04-07 — — WO disclosed
US-11246852-B2 Fast-acting plant-based medicinal compounds and nutritional supplements RECEPTOR HOLDINGS, INC. (US) 2022-02-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250268861-A1 N-ACYLATED FATTY AMINO ACIDS TO REDUCE ABSORPTION VARIABILITY IN CANNABINOID BASED COMPOSITIONS FAAH, CNR2, FABP2 ALOX5 206/4885NAAA 39/4885HTT 1270/4885
US-11246852-B2 Fast-acting plant-based medicinal compounds and nutritional supplements SLC1A5, SLC43A1, SLC27A2 ALOX5 330/4885NAAA 152/4885HTT 1152/4885
US-12303487-B2 N-acylated fatty amino acids to reduce absorption variability in cannabinoid based compositions FAAH, CNR2, FABP2 ALOX5 206/4885NAAA 39/4885HTT 1270/4885
US-20240261408-A1 FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS SLC1A5, SLC43A1, SLC27A2 ALOX5 330/4885NAAA 152/4885HTT 1152/4885
US-20250120939-A1 FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS SLC1A5, SLC43A1, SLC27A2 ALOX5 330/4885NAAA 152/4885HTT 1152/4885
US-20220133685-A1 FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS SLC1A5, SLC43A1, SLC27A2 ALOX5 330/4885NAAA 152/4885HTT 1152/4885
US-20250367295-A1 FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS SLC1A5, SLC43A1, SLC27A2 ALOX5 330/4885NAAA 152/4885HTT 1152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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