Salcaprozic Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ABCC8 ACE ADORA1 ADORA2A ADORA2B ADORA3 ALDH5A1 ALOX5 ALOX5AP ATP4A ATP4B BRAF CA1 CA12 CA2 CA4 CYSLTR1 DHFR DPEP1 EDNRA EDNRB ESR2 F10 FDPS FGF1 GABBR1 GABBR2 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ GART GNRHR GSC1 HMGCR IMPDH1 IMPDH2 KCNJ11 LY96 NOD2 NR3C1 NS3 NS4A NS5b P2RY1 P2RY12 P2RY2 P2RY4 P2RY6 PBP2X PDE3A PDE3B PDE4A PDE4B PDE4C PDE4D PDK1 PDK2 PDK3 PDK4 PPARG PPAT PTGIR PTGS1 PTGS2 RAF1 RYR1 RYR3 SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SERPINC1 SLC12A1 SLC12A3 SYK THRA THRB TLR3 TLR4 TLR9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 TYMS VKORC1 XDH bla blaIMP-1 blaOXA-33 blaOXA-58 blaT-3 blaT-4 blaT-5 blaT-6 dacA dacB dacC folA folP folP1 ftsI fusA gag gyrA gyrB mecA mrcA mrcB mrdA pbp1a pbp1b pbp2 pbp2a pbp2b pbp3 pbp4 pbpA pbpB pbpC pbpF pol ponB rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpoA rpoB rpoC rpoZ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Salcaprozic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

	gene	UniProt	supporting neighbours	confidence
▸	ALOX5 known ✓	P09917	3/20	0.60

▸	NAAA	Q02083	2/20	0.67

▸	HTT	P42858	3/20	0.58

▸	ALDH1A1	P00352	3/20	0.58

▸	TSHR	P16473	2/20	0.58

▸	HPGD	P15428	2/20	0.58

▸	NPC1	O15118	1/20	0.58

▸	MAPT	P10636	1/20	0.58

▸	NPSR1	Q6W5P4	1/20	0.58

▸	HSD17B10	Q99714	1/20	0.58

▸	NLRP1	Q9C000	1/20	0.58

▸	NAMPT	P43490	1/20	0.56

▸	HDAC7	Q8WUI4	1/20	0.51

▸	KDM4E	B2RXH2	2/20	0.50

▸	MEN1	O00255	1/20	0.46

▸	POLB	P06746	1/20	0.46

▸	KMT2A	Q03164	1/20	0.46

▸	ESRRG	P62508	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Salcaprozic Acid SCHEMBL29509907	1.00	NAAA (0.67)	NAAAALOX5HTTALDH1A1TSHR
Salcaprozic Acid SCHEMBL825599	1.00	NAAA (0.67)	NAAAALOX5HTTALDH1A1TSHR
SCHEMBL253212	1.00	NAAA (0.67)	NAAAALOX5HTTALDH1A1TSHR
SCHEMBL2331877	1.00	NAAA (0.67)	NAAAALOX5HTTALDH1A1TSHR
Salcaprozic Acid SCHEMBL26908047	0.97	NAAA (0.67)	NAAAALOX5HTTALDH1A1TSHR
Alcohol SCHEMBL2331970	0.95	NAAA (0.68)	NAAAALOX5HTTALDH1A1TSHR
SCHEMBL4956771	0.94	TSHR (0.61)	NAAAALOX5HTTALDH1A1TSHR
Salcaprozic Acid SCHEMBL29036081	0.90	NAAA (0.65)	NAAAALOX5HTTALDH1A1TSHR
Salcaprozic Acid SCHEMBL29036010	0.90	NAAA (0.65)	NAAAALOX5HTTALDH1A1TSHR
SCHEMBL823552	0.87	NAAA (0.84)	NAAAALOX5HTTALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240000879-A1	HERBAL COMPOSITIONS WITH IMPROVED BIOAVAILABILITY	SPOKE SCIENCES, INC. (US)	2024-01-04	—	—	US	claimed
US-20220133685-A1	FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS	RECEPTOR HOLDINGS, INC. (US)	2022-05-05	—	—	US	claimed
US-11246852-B2	Fast-acting plant-based medicinal compounds and nutritional supplements	RECEPTOR HOLDINGS, INC. (US)	2022-02-15	—	—	US	claimed
US-20210393575-A1	N-ACYLATED FATTY AMINO ACIDS TO REDUCE ABSORPTION VARIABILITY IN CANNABINOID BASED COMPOSITIONS	RECEPTOR HOLDINGS, INC. (US)	2021-12-23	—	—	US	claimed
US-20200268821-A1	HERBAL COMPOSITIONS WITH IMPROVED BIOAVAILABILITY	RECEPTOR HOLDINGS, INC. (US)	2020-08-27	—	—	US	claimed
US-20200254041-A1	RAPID ONSET AND EXTENDED ACTION PLANT-BASED AND SYNTHETIC CANNABINOID FORMULATIONS	RECEPTOR HOLDINGS, INC. (US)	2020-08-13	—	—	US	claimed
US-20200197521-A1	FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS	RECEPTOR HOLDINGS, INC. (US)	2020-06-25	—	—	US	claimed
US-20200101034-A1	RAPID AND CONTROLLED DELIVERY OF COMPOSITIONS WITH RESTORED ENTOURAGE EFFECTS	RECEPTOR HOLDINGS, INC. (US)	2020-04-02	—	—	US	claimed
US-20200078332-A1	FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS	RECEPTOR HOLDINGS, INC. (US)	2020-03-12	—	—	US	claimed
EP-3600436-A1	RAPID AND CONTROLLED DELIVERY OF COMPOSITIONS WITH RESTORED ENTOURAGE EFFECTS	Receptor Holdings, Inc. (US)	2020-02-05	—	—	EP	claimed
US-20190117778-A1	FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS	RECEPTOR LIFE SCIENCES, INC. (US)	2019-04-25	—	—	US	claimed
WO-2018175992-A1	RAPID AND CONTROLLED DELIVERY OF COMPOSITIONS WITH RESTORED ENTOURAGE EFFECTS	RECEPTOR LIFE SCIENCES (US)	2018-09-27	—	—	WO	claimed
US-20240000879-A1	HERBAL COMPOSITIONS WITH IMPROVED BIOAVAILABILITY	SPOKE SCIENCES, INC. (US)	2024-01-04	—	—	US	disclosed
US-20230075677-A1	FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS	RECEPTOR HOLDINGS, INC. (US)	2023-03-09	—	—	US	disclosed
US-20220133685-A1	FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS	RECEPTOR HOLDINGS, INC. (US)	2022-05-05	—	—	US	disclosed
US-11246852-B2	Fast-acting plant-based medicinal compounds and nutritional supplements	RECEPTOR HOLDINGS, INC. (US)	2022-02-15	—	—	US	disclosed
US-20200101034-A1	RAPID AND CONTROLLED DELIVERY OF COMPOSITIONS WITH RESTORED ENTOURAGE EFFECTS	RECEPTOR HOLDINGS, INC. (US)	2020-04-02	—	—	US	disclosed
US-10588974-B2	Fast-acting plant-based medicinal compounds and nutritional supplements	RECEPTOR HOLDINGS, INC. (US)	2020-03-17	—	—	US	disclosed
US-20200078332-A1	FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS	RECEPTOR HOLDINGS, INC. (US)	2020-03-12	—	—	US	disclosed
US-20190117778-A1	FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS	RECEPTOR LIFE SCIENCES, INC. (US)	2019-04-25	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20230075677-A1	FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS	SLC1A5, SLC43A1, SLC27A2	ALOX5 330/4885NAAA 152/4885HTT 1152/4885
US-20200254041-A1	RAPID ONSET AND EXTENDED ACTION PLANT-BASED AND SYNTHETIC CANNABINOID FORMULATIONS	FAAH, CNR1, GPR18	ALOX5 262/4885NAAA 6/4885HTT 2465/4885
US-11246852-B2	Fast-acting plant-based medicinal compounds and nutritional supplements	SLC1A5, SLC43A1, SLC27A2	ALOX5 330/4885NAAA 152/4885HTT 1152/4885
US-20200268821-A1	HERBAL COMPOSITIONS WITH IMPROVED BIOAVAILABILITY	SLC7A1, SLC1A5, SLC3A2	ALOX5 356/4885NAAA 444/4885HTT 2267/4885
US-20240000879-A1	HERBAL COMPOSITIONS WITH IMPROVED BIOAVAILABILITY	SLC7A1, SLC1A5, SLC3A2	ALOX5 356/4885NAAA 444/4885HTT 2267/4885
US-20200101034-A1	RAPID AND CONTROLLED DELIVERY OF COMPOSITIONS WITH RESTORED ENTOURAGE EFFECTS	FABP2, ASS1, AADAT	ALOX5 238/4885NAAA 88/4885HTT 1322/4885
US-20190117778-A1	FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS	SLC1A5, SLC43A1, SLC27A2	ALOX5 330/4885NAAA 152/4885HTT 1152/4885
US-10588974-B2	Fast-acting plant-based medicinal compounds and nutritional supplements	SLC1A5, SLC43A1, SLC27A2	ALOX5 330/4885NAAA 152/4885HTT 1152/4885
US-20210393575-A1	N-ACYLATED FATTY AMINO ACIDS TO REDUCE ABSORPTION VARIABILITY IN CANNABINOID BASED COMPOSITIONS	FAAH, CNR2, FABP2	ALOX5 206/4885NAAA 39/4885HTT 1270/4885
US-20220133685-A1	FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS	SLC1A5, SLC43A1, SLC27A2	ALOX5 330/4885NAAA 152/4885HTT 1152/4885
US-20200197521-A1	FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS	SLC1A5, SLC43A1, SLC27A2	ALOX5 330/4885NAAA 152/4885HTT 1152/4885
US-20200078332-A1	FAST-ACTING PLANT-BASED MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS	SLC1A5, SLC43A1, SLC27A2	ALOX5 330/4885NAAA 152/4885HTT 1152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.