SCHEMBL29511745

SCHEMBL29511745

CCC(C)C(NC(=O)C(CCC(=O)O)NC(=O)C(NC(=O)CN)C(C)C)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC1CSSCC2NC(=O)C(CCCCN)NC(=O)CNC(=O)C(Cc3ccccc3)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCSC)NC(=O)CNC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)NC(=O)C3CSSCC(C(=O)NC(C(=O)N4CCCC4C(=O)NC(CCCCN)C(=O)O)C(C)O)NC(=O)C(Cc4c[nH]cn4)NC(=O)C(CSSCC(NC(=O)C(CCC(N)=O)NC(=O)C4CCCN4C(=O)C(CO)NC(=O)CNC(=O)C(CO)NC1=O)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)N3)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(N)=O)NC(=O)C(CCSC)NC2=O)C(C)C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INSR P06213 1/20 0.61
NPY2R P49146 6/20 0.57
MC4R P32245 2/20 0.55
MC1R Q01726 2/20 0.55
MC3R P41968 1/20 0.55
F11 P03951 1/20 0.55
KCNMA1 Q12791 1/20 0.54
KCNMB4 Q86W47 1/20 0.54
KLK7 P49862 2/20 0.53
KCNA3 P22001 1/20 0.52
KCNA1 Q09470 1/20 0.52
RAMP1 O60894 1/20 0.52
RAMP2 O60895 1/20 0.52
RAMP3 O60896 1/20 0.52
CALCR P30988 1/20 0.52
CALCRL Q16602 1/20 0.52
ACE P12821 1/20 0.52
ACE2 Q9BYF1 1/20 0.52
KLK5 Q9Y337 1/20 0.52
TEAD1 P28347 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29965049 0.95 INSR (0.62) INSRNPY2RMC4RMC1RMC3R
SCHEMBL29387159 0.95 INSR (0.60) INSRNPY2RMC4RMC1RMC3R
SCHEMBL31736960 0.93 INSR (0.59) INSRNPY2RMC4RMC1RMC3R
SCHEMBL29964088 0.90 INSR (0.56) INSRNPY2RMC4RMC1RMC3R
SCHEMBL29387178 0.86 INSR (0.59) INSRNPY2RMC4RMC1RMC3R
SCHEMBL29904330 0.82 INSR (0.58) INSRNPY2RMC4RMC1RMC3R
SCHEMBL29390185 0.81 MC4R (0.63) INSRNPY2RMC4RMC1RMC3R
SCHEMBL29389145 0.80 MC4R (0.65) INSRNPY2RMC4RMC1RMC3R
SCHEMBL29393563 0.79 F11 (0.56) INSRNPY2RMC4RMC1RMC3R
SCHEMBL29412264 0.79 KCNA3 (0.57) INSRNPY2RMC4RMC1RMC3R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260043020-A1 BINDING MEMBERS WITH ALTERED DIVERSITY SCAFFOLD DOMAINS Maxion Therapeutics Limited (GB) 2026-02-12 US claimed
US-12606937-B2 Humanized antibodies with ultralong complementary determining regions TAURUS BIOSCIENCES, LLC (US) 2026-04-21 US disclosed
US-20260104424-A1 METHODS, SYSTEMS AND KITS FOR IDENTIFYING BIOACTIVE COMPOUNDS AND THERAPEUTIC METHODS AND COMPOSITIONS UNIV JOHNS HOPKINS (US) 2026-04-16 US disclosed
US-20260043020-A1 BINDING MEMBERS WITH ALTERED DIVERSITY SCAFFOLD DOMAINS Maxion Therapeutics Limited (GB) 2026-02-12 US disclosed
WO-2025241040-A1 PEPTIDES DERIVED FROM THE VENOM OF THE HETEROCTENUS JUNCEUS SCORPION, ITS VARIANTS, COMPOSITIONS, METHODS AND USES BLUE SCORPION GROUP INC (US) 2025-11-27 WO disclosed
US-12433949-B2 Sustained release delivery systems comprising traceless linkers NOVARTIS AG (CH) 2025-10-07 US disclosed
EP-4604984-A1 INHIBITORS Zealand Pharma A/S (DK) 2025-08-27 EP disclosed
US-20250230144-A1 QUINAZOLINES AS POTASSIUM ION CHANNEL INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2025-07-17 US disclosed
US-20250213627-A1 RECOMBINANT MICROORGANISM-BASED METHODS AND COMPOSITIONS FOR TREATMENT OF DISEASE BAYLOR COLLEGE OF MEDICINE (US) 2025-07-03 US disclosed
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC. 2024-11-14 US disclosed
WO-2022266494-A1 RIPPLED ANTIPARALLEL CROSS-BETA DIMERS AND RELATED MATERIALS, COMPOSITIONS AND METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-12-22 WO disclosed
US-11530493-B2 Humanized antibodies with ultralong complementary determining regions TAURUS BIOSCIENCES, LLC (US) 2022-12-20 US disclosed
US-11484576-B2 Methods of promoting corticospinal neuronal outgrowth in neuronal lesions using a pro-regenerative human osteopontin fragment THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2022-11-01 US disclosed
US-20220324836-A1 QUINAZOLINES AS POTASSIUM ION CHANNEL INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2022-10-13 US disclosed
WO-2022200374-A1 KV1.3 BLOCKERS ZEALAND PHARMA A/S (DK) 2022-09-29 WO disclosed
US-20220251151-A1 KV1.3 BLOCKERS ZEALAND PHARMA A/S (DK) 2022-08-11 US disclosed
EP-4031162-A1 KV1.3 BLOCKERS Zealand Pharma A/S (DK) 2022-07-27 EP disclosed
US-11331393-B2 Renal-homing peptide conjugates and methods of use thereof Blaze Bioscience, Inc. (US) 2022-05-17 US disclosed
US-11292820-B2 KV1.3 blockers ZEALAND PHARMA A/S (DK) 2022-04-05 US disclosed
US-11278595-B2 Peptides comprising non-natural amino acids and methods of making and using the same LONGEVITY BIOTECH, INC. (US) 2022-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606937-B2 Humanized antibodies with ultralong complementary determining regions IGLV6-57, FCGR3B, VSIR INSR 1021/4885NPY2R 340/4885MC4R 1349/4885
US-20220324836-A1 QUINAZOLINES AS POTASSIUM ION CHANNEL INHIBITORS KCNJ4, KCNK4, KCNQ4 INSR 245/4885NPY2R 537/4885MC4R 1206/4885
US-20250230144-A1 QUINAZOLINES AS POTASSIUM ION CHANNEL INHIBITORS KCNJ4, KCNK4, KCNQ4 INSR 245/4885NPY2R 537/4885MC4R 1206/4885
US-11331393-B2 Renal-homing peptide conjugates and methods of use thereof CXCL12, ATP6V1B1, VIP INSR 1596/4885NPY2R 674/4885MC4R 1472/4885
US-20260104424-A1 METHODS, SYSTEMS AND KITS FOR IDENTIFYING BIOACTIVE COMPOUNDS AND THERAPEUTIC METHODS AND COMPOSITIONS VIP, SYNCRIP, MTREX INSR 2291/4885NPY2R 832/4885MC4R 2083/4885
US-12433949-B2 Sustained release delivery systems comprising traceless linkers ABCB11, ABCB1, GHRHR INSR 782/4885NPY2R 633/4885MC4R 3990/4885
US-11278595-B2 Peptides comprising non-natural amino acids and methods of making and using the same APLNR, SCTR, GIPR INSR 23/4885NPY2R 183/4885MC4R 451/4885
US-11292820-B2 KV1.3 blockers KCNA3, KCNK3, KCNN3 INSR 2284/4885NPY2R 1696/4885MC4R 1538/4885
US-20260043020-A1 BINDING MEMBERS WITH ALTERED DIVERSITY SCAFFOLD DOMAINS VSIG8, CDR2, VSIR INSR 3832/4885NPY2R 3884/4885MC4R 4508/4885
US-20220251151-A1 KV1.3 BLOCKERS KCNA3, KCNK3, KCNN3 INSR 2284/4885NPY2R 1696/4885MC4R 1538/4885
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME SCTR, GIPR, APLNR INSR 15/4885NPY2R 129/4885MC4R 528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.