SCHEMBL29535716

SCHEMBL29535716

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(C)C)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.71

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CALCA P06881 2/20 0.71
▸ NPY1R P25929 1/20 0.66
▸ NPY2R P49146 1/20 0.66
▸ NPY4R P50391 1/20 0.66
▸ NPY5R Q15761 1/20 0.66
▸ GNRHR P30968 1/20 0.62
▸ CXCR4 P61073 4/20 0.62
▸ GLP1R P43220 10/20 0.62
▸ NMBR P28336 1/20 0.61
▸ GRPR P30550 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31060386 0.90 CALCA (0.75) CALCANPY1RNPY2RNPY4RNPY5R
SCHEMBL30429251 0.89 CALCA (0.62) CALCANPY1RNPY2RNPY4RNPY5R
SCHEMBL30523133 0.87 GLP1R (0.71) CALCANPY1RNPY2RNPY4RNPY5R
SCHEMBL30932197 0.87 GLP1R (0.71) CALCANPY1RNPY2RNPY4RNPY5R
SCHEMBL31251982 0.86 CALCA (0.90) CALCANPY1RNPY2RNPY4RNPY5R
SCHEMBL29992945 0.86 CALCA (0.59) CALCANPY1RNPY2RNPY4RNPY5R
Exenatide SCHEMBL30947451 0.84 GLP1R (0.79) GLP1R
SCHEMBL29358003 0.84 NR3C1 (0.66) GLP1R
SCHEMBL29351953 0.84 NPY2R (0.74) CALCANPY1RNPY2RNPY4RNPY5R
SCHEMBL29983249 0.84 NR3C1 (0.69) GLP1RGRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260140121-A1 METHODS OF QUANTIFYING FRATAXIN AND FRATAXIN FUSION PROTEINS LARIMAR THERAPEUTICS INC (US) 2026-05-21 — — US disclosed
US-20260110698-A1 METHODS FOR QUANTIFYING FRATAXIN ACTIVITY LARIMAR THERAPEUTICS INC (US) 2026-04-23 — — US disclosed
US-12577602-B2 Compositions and methods for peptide production BIOCATALYST LLC (US) 2026-03-17 — — US disclosed
US-12566178-B2 Methods of quantifying frataxin and frataxin fusion proteins LARIMAR THERAPEUTICS, INC. (US) 2026-03-03 — — US disclosed
WO-2025261963-A1 THERAPEUTIC DELIVERY COMPOSITIONS UNITED KINGDOM RESEARCH AND INNOVATION (GB) 2025-12-26 — — WO disclosed
EP-4638483-A1 GALANIN-2 RECEPTOR AGONISTS LifeArc (GB) 2025-10-29 — — EP disclosed
US-12411145-B2 Methods for quantifying frataxin activity LARIMAR THERAPEUTICS, INC. (US) 2025-09-09 — — US disclosed
US-12351611-B2 Molecules for organelle-specific protein delivery LARIMAR THERAPEUTICS, INC. (US) 2025-07-08 — — US disclosed
CN-120154732-A Combination comprising a galanin receptor GAL2R agonist for the treatment of multiple sclerosis 深圳先进技术研究院 2025-06-17 — — CN disclosed
US-20250085297-A1 METHODS FOR QUANTIFYING FRATAXIN ACTIVITY LARIMAR THERAPEUTICS, INC. 2025-03-13 — — US disclosed
US-20240026414-A1 Compositions and Methods for Peptide Production BIOCATALYST LLC (US) 2024-01-25 — — US disclosed
US-11802301-B2 Compositions and methods for peptide production BIOCATALYST LLC (US) 2023-10-31 — — US disclosed
US-20230193342-A1 Compositions and Methods for Peptide Production BIOCATALYST LLC (US) 2023-06-22 — — US disclosed
US-20230075121-A1 CELL-PENETRATING COMPSTATIN ANALOGS AND USES THEREOF APELLIS PHARMACEUTICALS, INC. 2023-03-09 — — US disclosed
CN-115725000-A Double-label recombinant protein for expressing and purifying small peptide and preparation method and application thereof 中国科学技术大学 2023-03-03 — — CN disclosed
US-20220378869-A1 USE OF FRATAXIN FOR TREATING LEIGH SYNDROME, FRENCH CANADIAN TYPE LARIMAR THERAPEUTICS, INC. 2022-12-01 — — US disclosed
US-20220287968-A1 LIPID VESICLE-MEDIATED DELIVERY TO CELLS FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2022-09-15 — — US disclosed
US-20220265843-A1 EXTRACELLULAR VESICLE-MEDIATED DELIVERY TO CELLS FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2022-08-25 — — US disclosed
US-11407789-B2 Cell-penetrating compstatin analogs and uses thereof APELLIS PHARMACEUTICALS, INC. (US) 2022-08-09 — — US disclosed
US-20220088131-A1 COMPOSITIONS AND METHODS RELATING TO C5L2 KING'S COLLEGE LONDON (GB) 2022-03-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577602-B2 Compositions and methods for peptide production LNPEP, CPN1, PRCP CALCA 52/4885NPY1R 509/4885NPY2R 824/4885
US-12566178-B2 Methods of quantifying frataxin and frataxin fusion proteins FGB, GZMB, TAF15 CALCA 575/4885NPY1R 385/4885NPY2R 677/4885
US-20230075121-A1 CELL-PENETRATING COMPSTATIN ANALOGS AND USES THEREOF C9, C3AR1, SERPINC1 CALCA 176/4885NPY1R 3275/4885NPY2R 3717/4885
US-20260110698-A1 METHODS FOR QUANTIFYING FRATAXIN ACTIVITY ATXN2L, XDH, CYFIP1 CALCA 1825/4885NPY1R 482/4885NPY2R 997/4885
US-20260140121-A1 METHODS OF QUANTIFYING FRATAXIN AND FRATAXIN FUSION PROTEINS TFAM, TIMM10, AFG3L2 CALCA 671/4885NPY1R 436/4885NPY2R 446/4885
US-11407789-B2 Cell-penetrating compstatin analogs and uses thereof C9, C3AR1, SERPINC1 CALCA 172/4885NPY1R 3248/4885NPY2R 3688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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